Human Tumor Cell Urokinase-Type Plasminogen Activator (uPA): Degradation of the Proenzyme form (pro-uPA) by Granulocyte Elastase Prevents Subsequent Activation by Plasmin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Protein Sequence Determination

1975 • 839 citations

Haemostasis and Thrombosis.

1982 • 688 citations

The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin.

1986 • 391 citations

Thrombosis and haemostasis

1988 • 327 citations

The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain

1982 • 312 citations

Surface receptors for urokinase plasminogen activator

1988 • 222 citations

Haemostasis and Thrombosis

1988 • 221 citations

The primary structure of high molecular mass urokinase from human urine

1982 • 191 citations

Urokinase-type plasminogen activator (u-PA) antigen is a predictor of early relapse in breast cancer

1990 • 189 citations

Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor.

1989 • 182 citations

Content and characterization of plasminogen activators in human lung tumors and normal lung tissue.

1980 • 179 citations

Proliferation of a human epidermal tumor cell line stimulated by urokinase

1987 • 132 citations

Plasminogen activator activity and composition in human breast cancer.

1982 • 123 citations

The Relevance of Plasminogen Activators to Neoplastic Growth

1988 • 97 citations

A review of recent literature

1981 • 97 citations

Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

1987 • 92 citations

Plasminogen activator profiles in neoplastic tissues of the human colon.

1988 • 85 citations

Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiency.

1986 • 83 citations

Inactivation of single-chain urokinase (pro-urokinase) by thrombin and thrombin-like enzymes: relevance of the findings to the interpretation of fibrin-binding experiments

1987 • 74 citations

Human neutrophil plasminogen activator is localized in specific granules and is translocated to the cell surface by exocytosis.

1986 • 74 citations

Sensitive and specific enzyme-linked immunosorbent assay for urokinase-type plasminogen activator and its application to plasma from patients with breast cancer.

1988 • 73 citations

Isolation and characterization of plasminogen activators from hyperlastic and malignant prostate tissue

1984 • 57 citations

Fibrin-fibronectin compounds in human ovarian tumor ascites and their possible relation to the tumor stroma.

1988 • 44 citations

Reversible independent unfolding of the domains of urokinase monitored by proton NMR

1989 • 42 citations

[Clinical aspects of fibrinolysis].

1965 • 41 citations

The contribution of leukocyte proteases to fibrinolysis

1986 • 40 citations

Synthetic Peptide Substrate Assays in Coagulation and Fibrinolysis and Their Application on Automates

1983 • 32 citations

Influence of detergents on the measurement of the fibrinolytic activity of plasminogen activators

1982 • 32 citations

Elastase released from human granulocytes stimulated with N‐formyl‐chemotactic peptide prevents activation of tumor cell prourokinase (pro‐uPA)

1989 • 30 citations

Tissue Plasminogen Activator and Urokinase in Normal, Dysplastic and Cancerous Squamous Epithelium of the Uterine Cervix

1987 • 20 citations

Alveolar macrophage modulation of proteolysis by neutrophil elastase in extracellular matrix.

1984 • 14 citations

Elastase digested urokinase (ED-UK)

1985 • 4 citations