Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiency.

Measurement of Fibrinopeptide A in Human Blood

1974 • 547 citations

Elastase in Tissue Injury

1985 • 512 citations

A two-step fibrinogen–fibrin transition in blood coagulation

1978 • 472 citations

The Neutral Proteases of Human Granulocytes

1973 • 366 citations

In vitro suppression of serum elastase-inhibitory capacity by reactive oxygen species generated by phagocytosing polymorphonuclear leukocytes.

1979 • 293 citations

Potential Mediator of Inflammation

1980 • 255 citations

Proteolysis by Neutrophils

1982 • 244 citations

Demonstration of granulocytic proteases in plasma of patients with acute leukemia and septicemia with coagulation defects

1977 • 226 citations

Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G Inhibition with peptide chloromethyl ketones

1977 • 224 citations

Myeloperoxidase-catalyzed inactivation of alpha 1-protease inhibitor by human neutrophils.

1981 • 222 citations

Human plasma kallikrein releases neutrophil elastase during blood coagulation.

1983 • 221 citations

Proteolytic cleavage and inactivation of alpha 2-plasmin inhibitor and C1 inactivator by human polymorphonuclear leukocyte elastase.

1982 • 207 citations

Leukocyte Elastase Release during Blood Coagulation

1982 • 204 citations

An alternative pathway for fibrinolysis. I. The cleavage of fibrinogen by leukocyte proteases at physiologic pH.

1975 • 199 citations

Chemical Synthesis of Peptides and Proteins

1970 • 170 citations

Degradation of Human Fibrinogen by Plasma α2-Macroglobulin-Enzyme Complexes

1973 • 156 citations

Neutral Proteases of Human Granulocytes III. Interaction between Human Granulocyte Elastase and Plasma Protease Inhibitors

1974 • 153 citations

Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages.

1979 • 132 citations

Isolation of Elastase-Like and Chymotrypsin-Like Neutral Proteases from Human Granulocytes

1974 • 129 citations

The degradation of human lung elastin by neutrophil proteinases

1980 • 129 citations

Elastase of U-937 Monocytelike Cells

1982 • 126 citations

Relative proteolysis of the fibrinogen Bβ chain by thrombin and plasmin as a determinant of thrombosis

1981 • 126 citations

Sequence of Fibrinogen Proteolysis and Platelet Release after Intrauterine Infusion of Hypertonic Saline

1979 • 106 citations

Elevated factor Xa activity in the blood of asymptomatic patients with congenital antithrombin deficiency.

1985 • 103 citations

Substrate specificity of the elastase and the chymotrypsin-like enzyme of the human granulocyte

1977 • 99 citations

Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor.

1982 • 96 citations

[52] Human α2-macroglobulin

1976 • 96 citations

Alpha-1-antitrypsin-human leukocyte elastase complexes in blood: quantification by an enzyme-linked differential antibody immunosorbent assay and comparison with alpha-2-plasmin inhibitor-plasmin complexes

1983 • 96 citations

Radioimmunoassay of human fibrinopeptide B and kinetics of fibrinopeptide cleavage by different enzymes.

1975 • 95 citations

The major fibrinolytic proteases of human leukocytes

1980 • 86 citations

Leukocytes and Thrombosis

1965 • 81 citations

Unique pattern of fibrinogen cleavage by human leukocyte proteases

1977 • 71 citations

Degradation products of fibrinogen by elastase-like neutral protease from human granulocytes. Characterization and effects on blood coagulation in vitro.

1978 • 68 citations

Importance of neutrophilic leukocytes in the resolution of fibrin.

1965 • 56 citations

Action of human lysosomal elastase on the oxidized B chain of insulin

1977 • 55 citations

[48] Plasminogen

1974 • 52 citations

Elastase-like enzymes in skin fibroblasts and rat aorta smooth muscle cells

1980 • 48 citations

Elastase in Tissue Injury

1985 • 47 citations

Properties and subcellular localization of elastase-like activities of arterial smooth muscle cells in culture

1983 • 42 citations

Release of Elastolytic Activity from Blood Platelets

1970 • 40 citations

1. PLASMIC DEGRADATION OF FIBRINOGEN

1971 • 35 citations

Immunochemical discrimination of leukocyte elastase from plasmic degradation products of fibrinogen.

1983 • 34 citations

Reactivity of fibrinogen and fibrinopeptide A containing fibrinogen fragments with antisera to fibrinopeptide A

1976 • 34 citations

Substrate hydrolysis by immune complex-activated neutrophils: effect of physical presentation of complexes and protease inhibitors.

1981 • 32 citations

Specificity of Antisera to Human Fibrinopeptide A Used in Clinical Fibrinopeptide A Assays

1976 • 31 citations

The specificity of macrophage elastase on the insulin B-chain

1981 • 29 citations

Elastase-α1antitrypsin complexes in acute leukaemia

1985 • 19 citations

Unique pattern of fibrinogen cleavage by human leukocyte proteases

1977 • 5 citations