FTY720 Attenuates Hepatic Ischemia-Reperfusion Injury in Normal and Cirrhotic Livers

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart

2000 • 834 citations

Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning

2003 • 826 citations

Akt Phosphorylates and Negatively Regulates Apoptosis Signal-Regulating Kinase 1

2001 • 700 citations

Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo

2001 • 686 citations

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

2000 • 458 citations

17 beta-Estradiol attenuates voltage-dependent Ca2+ currents in A7r5 vascular smooth muscle cell line

1994 • 342 citations

Endothelin-1 induces direct constriction of hepatic sinusoids

1994 • 300 citations

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

2002 • 265 citations

Graft Injury in Relation to Graft Size in Right Lobe Live Donor Liver Transplantation

2003 • 237 citations

Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: Implications of a central role for nuclear factor ?B

1999 • 216 citations

Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols

2000 • 214 citations

A20 Inhibits Tumor Necrosis Factor (TNF) Alpha-Induced Apoptosis by Disrupting Recruitment of TRADD and RIP to the TNF Receptor 1 Complex in Jurkat T Cells

2002 • 198 citations

Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice

2001 • 194 citations

Endothelin-1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbances

1994 • 157 citations

A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis

2002 • 146 citations

MOLECULAR MECHANISMS OF HEPATIC ISCHEMIAREPERFUSION INJURY AND PRECONDITIONING

2003 • 119 citations

Endothelial exposure to hypoxia induces Egr‐1 expression involving PKCα‐mediated Ras/Raf‐1/ERK1/2 pathway

2001 • 98 citations

Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats

2003 • 95 citations

Rapid Activation of Protein Kinase B/Akt Has a Key Role in Antiapoptotic Signaling during Liver Regeneration

2000 • 85 citations

FTY720, a New Immunosuppressant, Promotes Long-Term Graft Survival and Inhibits the Progression of Graft Coronary Artery Disease in a Murine Model of Cardiac Transplantation

1999 • 81 citations

Distinct intragraft response pattern in relation to graft size in liver transplantation

2003 • 75 citations

FTY720 Pretreatment Reduces Warm Hepatic Ischemia Reperfusion Injury Through Inhibition of T-Lymphocyte Infiltration

2002 • 72 citations

FK 409 Ameliorates Small-for-Size Liver Graft Injury by Attenuation of Portal Hypertension and Down-Regulation of Egr-1 Pathway

2004 • 67 citations

Intragraft gene expression profiles by cDNA microarray in small-for-size liver grafts

2003 • 65 citations

Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture

2000 • 61 citations

Macrophage inflammatory protein-2 induced by TNF-α plays a pivotal role in concanavalin A-induced liver injury in mice

2001 • 52 citations

FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines

2001 • 48 citations

Hyperoxia induces Egr‐1 expression through activation of extracellular signal‐regulated kinase 1/2 pathway

2003 • 47 citations

FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells

2003 • 43 citations

FTY 720 prevents ischemic reperfusion damage in rat kidneys

2001 • 40 citations

Heat‐shock protein 70 favours human liver recovery from ischaemia‐reperfusion

2003 • 26 citations

Ischemic injury in cirrhotic livers: An experimental study of the temporary arrest of hepatic circulation

1992 • 18 citations

Hepatic tissue microcirculation, oxygenation and energy charge in ischemia-reperfusion subjected cirrhotic rat liver.

1997 • 6 citations