Immunotherapy with OX40L‐Fc or anti‐CTLA‐4 enhances local tissue responses and killing of Leishmania donovani

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

2002 • 1,733 citations

Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

1999 • 1,000 citations

CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy

2001 • 964 citations

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda

2002 • 777 citations

OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

2001 • 638 citations

The Emerging Role of CTLA-4 as an Immune Attenuator

1997 • 637 citations

The Role of CD40 Ligand in Costimulation and T‐Cell Activation

1996 • 441 citations

The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function

2001 • 413 citations

Engagement of the OX-40 Receptor In Vivo Enhances Antitumor Immunity

2000 • 386 citations

Chemotherapy of Leishmaniasis

2002 • 378 citations

Interleukin-10 (IL-10) in Experimental Visceral Leishmaniasis and IL-10 Receptor Blockade as Immunotherapy

2002 • 246 citations

CD4+ regulatory T cells

2001 • 241 citations

Tissue granuloma structure‐function in experimental visceral leishmaniasis

2001 • 200 citations

B Cell-Deficient Mice Are Highly Resistant to Leishmania donovani Infection, but Develop Neutrophil-Mediated Tissue Pathology

2000 • 194 citations

Sodium Stibogluconate Is a Potent Inhibitor of Protein Tyrosine Phosphatases and Augments Cytokine Responses in Hemopoietic Cell Lines

2001 • 184 citations

Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis

2002 • 177 citations

Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control ofLeishmania donovani

1998 • 166 citations

Intracellular Antimicrobial Activity in the Absence of Interferon-γ: Effect of Interleukin-12 in Experimental Visceral Leishmaniasis in Interferon-γ Gene-disrupted Mice

1997 • 162 citations

The Early IL-4 Response toLeishmania majorand the Resulting Th2 Cell Maturation Steering Progressive Disease in BALB/c Mice Are Subject to the Control of Regulatory CD4+CD25+ T Cells

2002 • 146 citations

Blockade of CTLA-4 Enhances Host Resistance to the Intracellular Pathogen,Leishmania donovani

1998 • 135 citations

A Role for Tumor Necrosis Factor-α in Remodeling the Splenic Marginal Zone during Leishmania donovani Infection

2002 • 124 citations

Deficient expression of co‐stimulatory molecules on Leishmania‐infected macrophages

1994 • 123 citations

Negative Regulation of T Cell Receptor–Lipid Raft Interaction by Cytotoxic T Lymphocyte–associated Antigen 4

2003 • 122 citations

Interleukin‐12 Regulates the Response to Chemotherapy in Experimental Visceral Leishmaniasis

2000 • 115 citations

OX40: targeted immunotherapy - implications for tempering autoimmunity and enhancing vaccines

2002 • 112 citations

TGF-β Mediates CTLA-4 Suppression of Cellular Immunity in Murine Kalaazar

2000 • 104 citations

Macrophage‐T cell interaction in experimental visceral leishmaniasis: failure to express costimulatory molecules on Leishmania‐infected macrophages and its implication in the suppression of cell‐mediated immunity

1995 • 95 citations

Oral treatment of visceral leishmaniasis with miltefosine

1999 • 94 citations

Survival in human colorectal cancer correlates with expression of the T-cell costimulatory molecule OX-40 (CD134)

2002 • 90 citations

Induction of Anti-Mammary Cancer Immunity by Engaging the OX-40 Receptor in Vivo

2001 • 80 citations

Augmentation Versus Inhibition: Effects of Conjunctional OX-40 Receptor Monoclonal Antibody and IL-2 Treatment on Adoptive Immunotherapy of Advanced Tumor

2001 • 78 citations

Effect of Continuous Administration of Interferon- in Experimental Visceral Leishmaniasis

1990 • 69 citations

Modulation of T-Cell Costimulation as Immunotherapy or Immunochemotherapy in Experimental Visceral Leishmaniasis

2003 • 64 citations

CD95 is required for the early control of parasite burden in the liver ofLeishmania donovani-infected mice

2001 • 57 citations

Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation

2001 • 57 citations

Anin VivoAnalysis of Cytokine Production duringLeishmania donovaniInfection inscidMice

1996 • 52 citations

OX40 Ligation on Activated T Cells Enhances the Control ofCryptococcus neoformansand Reduces Pulmonary Eosinophilia

2003 • 46 citations

Novel therapeutics for the treatment of graft-versus-host disease

2002 • 29 citations