Lymphocytes and ischemia-reperfusion injury

Pathophysiology of ischaemia-reperfusion injury

2000 • 1,664 citations

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury.

1996 • 723 citations

Role of T Lymphocytes and Interferon-γ in Ischemic Stroke

2006 • 659 citations

Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury.

1994 • 495 citations

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1994 • 462 citations

In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

1993 • 452 citations

Vascular ischaemia and reperfusion injury

2004 • 445 citations

Inflammatory cells in ischemic acute renal failure

2004 • 441 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 419 citations

Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement.

1996 • 378 citations

Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury

2000 • 368 citations

CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver.

1997 • 365 citations

T- and B-Cell-Deficient Mice with Experimental Stroke have Reduced Lesion Size and Inflammation

2007 • 351 citations

Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice

2000 • 344 citations

New Cellular and Molecular Immune Pathways in Ischemia/Reperfusion Injury

2006 • 308 citations

Lymphocytic Infiltration and Expression of Intercellular Adhesion Molecule-1 in Photochemically Induced Ischemia of the Rat Cortex

1995 • 286 citations

Local immune responses in the rat cerebral cortex after middle cerebral artery occlusion

1994 • 268 citations

Carbon Monoxide Produced by Heme Oxygenase-1 Suppresses T Cell Proliferation via Inhibition of IL-2 Production

2004 • 264 citations

Myocardial Infarct–Sparing Effect of Adenosine A _2A Receptor Activation Is due to Its Action on CD4 ⁺ T Lymphocytes

2006 • 252 citations

Intestinal reperfusion injury is mediated by IgM and complement

1999 • 246 citations

Impaired Arteriogenic Response to Acute Hindlimb Ischemia in CD4-Knockout Mice

2003 • 244 citations

Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium.

1993 • 238 citations

EFFECTS OF INITIAL ISCHEMIA/REPERFUSION INJURY ON THE TRANSPLANTED KIDNEY1

1997 • 237 citations

Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factorin situ

2003 • 231 citations

The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury.

1997 • 228 citations

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

2006 • 226 citations

Protection Against Ischemia/Reperfusion Injury in Cardiac and Renal Transplantation with Carbon Monoxide, Biliverdin and Both

2005 • 223 citations

Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury

2004 • 222 citations

Carbon Monoxide Inhalation Protects Rat Intestinal Grafts from Ischemia/Reperfusion Injury

2003 • 192 citations

Long-term effects of acute ischemia and reperfusion injury

2004 • 190 citations

B Cell Deficiency Confers Protection from Renal Ischemia Reperfusion Injury

2003 • 188 citations

Mice Deficient in Complement Receptors 1 and 2 Lack a Tissue Injury-Inducing Subset of the Natural Antibody Repertoire

2002 • 183 citations

Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury

2003 • 160 citations

The T cell as a bridge between innate and adaptive immune systems: Implications for the kidney

2002 • 157 citations

Role of CD11a and CD11b in ischemic acute renal failure in rats

1994 • 150 citations

Ischemia–reperfusion and immediate T cell responses

2007 • 149 citations

Role of selectins in local and remote tissue injury following ischemia and reperfusion.

1994 • 143 citations

CD8 ⁺ T Lymphocytes Regulate the Arteriogenic Response to Ischemia by Infiltrating the Site of Collateral Vessel Development and Recruiting CD4 ⁺ Mononuclear Cells Through the Expression of Interleukin-16

2005 • 139 citations

Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia

2001 • 137 citations

Natural Killer Cells and CD4 ⁺ T-Cells Modulate Collateral Artery Development

2007 • 136 citations

Chemokines and their receptors as markers of allograft rejection and targets for immunosuppression

2003 • 131 citations

CD40/CD40 Ligand Signaling in Mouse Cerebral Microvasculature After Focal Ischemia/Reperfusion

2005 • 131 citations

Prevention of kidney allograft rejection using anti-CD40 and anti-CD86 in primates

2003 • 126 citations

S1P1-selective agonist, SEW2871, ameliorates ischemic acute renal failure

2006 • 123 citations

CD4+ T cells contribute to postischemic liver injury in mice by interacting with sinusoidal endothelium and platelets

2006 • 118 citations

Reperfusion Injury

2006 • 118 citations

Carbon Monoxide Inhibits T Lymphocyte Proliferation via Caspase-Dependent Pathway

2004 • 117 citations

Endothelial injury and dysfunction in ischemic acute renal failure

2002 • 116 citations

Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection

2003 • 109 citations

CD28-B7 blockade in organ dysfunction secondary to cold ischemia/reperfusion injury: Rapid Communication

1997 • 106 citations

Role of the T-cell receptor in kidney ischemia–reperfusion injury

2006 • 105 citations

Small molecule selectin ligand inhibition improves outcome in ischemic acute renal failure

2001 • 103 citations

Recipient T Cells Mediate Reperfusion Injury after Lung Transplantation in the Rat

2003 • 103 citations

Effects of Combined T- and B-Cell Deficiency on Murine Ischemia Reperfusion Injury

2005 • 97 citations

Functional Activity of Natural Antibody is Altered in Cr2-Deficient Mice

2002 • 95 citations

Carbon monoxide inhalation ameliorates cold ischemia/reperfusion injury after rat liver transplantation

2005 • 95 citations

Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts

2006 • 92 citations

The role of adhesion molecules and T cells in ischemic renal injury

2003 • 92 citations

The role of natural IgM in myocardial ischemia–reperfusion injury

2006 • 92 citations

FTY720, a New Immunosuppressant, Promotes Long-Term Graft Survival and Inhibits the Progression of Graft Coronary Artery Disease in a Murine Model of Cardiac Transplantation

1999 • 81 citations

T-lymphocytes modulate the microvascular and inflammatory responses to intestinal ischemia-reperfusion.

2002 • 79 citations

A sphingosine-1-phosphate type 1 receptor agonist inhibits the early T-cell transient following renal ischemia–reperfusion injury

2007 • 75 citations

Heart Allograft Protection with Low-Dose Carbon Monoxide Inhalation: Effects on Inflammatory Mediators and Alloreactive T-cell Responses

2006 • 73 citations

The Differing Roles of the Classical and Mannose-Binding Lectin Complement Pathways in the Events following Skeletal Muscle Ischemia-Reperfusion

2006 • 71 citations

Pathomechanisms of Ischemia-Reperfusion Injury as the Basis for Novel Preventive Strategies: Is It Time for the Introduction of Pleiotropic Compounds?

2007 • 71 citations

T-Lymphocytes Modulate the Microvascular and Inflammatory Responses to Intestinal Ischemia-Reperfusion

2002 • 67 citations

Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM

2004 • 64 citations

In Vivo Visualization of the Effect of Polyclonal Antithymocyte Globulins on the Microcirculation after Ischemia/Reperfusion in a Primate Model

2006 • 64 citations

Role of α/β and γ/δ T cells in renal ischemia-reperfusion injury

2007 • 62 citations

Decreased lung ischemia-reperfusion injury in rats after preoperative administration of cyclosporine and tacrolimus

2002 • 60 citations

Hemorrhagic infarction: A reperfusion injury following prolonged myocardial ischemic anoxia.

1975 • 57 citations

Chemokine receptor‐dependent alloresponses

2003 • 57 citations

Neutrophils do not contribute to infarction, oxidative stress, and NO synthase activity in severe brain ischemia

2003 • 48 citations

FTY720-induced lymphocyte homing modulates post-transplant preservation/reperfusion injury

2004 • 47 citations

Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM

2006 • 47 citations

Influence of polyclonal anti-thymocyte globulins upon ischemia–reperfusion injury in a non-human primate model

2006 • 47 citations

CD4+CD25+ Regulatory T-Cells Inhibit the Islet Innate Immune Response and Promote Islet Engraftment

2006 • 41 citations

The CD154-CD40 T-Cell Co-stimulation Pathway in Liver Ischemia and Reperfusion Inflammatory Responses

2005 • 40 citations

Immune Responses in Kidney Preservation and Reperfusion Injury

2004 • 37 citations

Reduction of Ischemia–Reperfusion Injury in the Rat Kidney by FTY720, a Synthetic Derivative of Sphingosine

2007 • 36 citations

Copolymer-1 (Cop-1) improves neurological recovery after middle cerebral artery occlusion in rats

2007 • 32 citations

Disruption of P-Selectin Signaling Modulates Cell Trafficking and Results in Improved Outcomes after Mouse Warm Intestinal Ischemia and Reperfusion Injury

2005 • 32 citations

Protective role of selectin ligand inhibition in a large animal model of kidney ischemia–reperfusion injury

2006 • 31 citations

Suppressed endothelin-1 production by FK506 and cyclosporin A in ischemia/reperfusion of rat small intestine

1999 • 30 citations

A Novel CCR5/CXCR3 Antagonist Protects Intestinal Ischemia/Reperfusion Injury

2006 • 25 citations

FTY720 Reduces Extracellular Matrix Expansion Associated With Ischemia-Reperfusion Induced Injury

2007 • 24 citations

Effects of a phenolic compound, resveratrol, on the renal function and costimulatory adhesion molecule CD86 expression in rat kidneys with ischemia/reperfusion injury

2005 • 23 citations

Anti-Ischemic Effect of Selectin Blocker Through Modulation of Tumor Necrosis Factor-α and Interleukin-10

2007 • 18 citations

FK 506 protects brain tissue in animal models of stroke

2001 • 18 citations

P-selectin knockout mice have improved outcomes with both warm ischemia and small bowel transplantation

2004 • 18 citations

The Importance of Lymphocytes in Lung Ischemia-Reperfusion Injury

2007 • 17 citations

Immunophilin ligands FK506 and cyclosporine A improve neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits

2004 • 17 citations

FTY720 for Treatment of Ischemia–Reperfusion Injury Following Complete Renal Ischemia; Impact on Long-Term Survival and T-Lymphocyte Tissue Infiltration

2007 • 15 citations

Protective effects of FTY720 on chronic allograft nephropathy by reducing late lymphocytic infiltration

2004 • 13 citations

Immune Responses in Kidney Preservation and Reperfusion Injury

2004 • 12 citations

The effect of cyclosporine in gut ischemic injury: A computerized morphometric and enzymatic analysis

1996 • 12 citations

FTY720 for Treatment of Ischemia-Reperfusion Injury Following Complete Renal Ischemia in C57/BL6 Mice

2006 • 12 citations

REGULATORY T CELLS (CD4+CD25+) IN KIDNEY ISCHEMIA REPERFUSION INJURY.

2006 • 4 citations

Establishment of linkage analysis strategy for autosomal dominant polycystic kidney disease

2000 • 1 citations

Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin

2007 • 1 citations