CD4+CD25+ Regulatory T-Cells Inhibit the Islet Innate Immune Response and Promote Islet Engraftment

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

2000 • 2,211 citations

CD4+CD25+ suppressor T cells: more questions than answers

2002 • 2,202 citations

CD4+CD25high Regulatory Cells in Human Peripheral Blood

2001 • 1,882 citations

Immunologic tolerance maintained by CD25⁺ CD4⁺ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

2001 • 1,515 citations

Role of LAG-3 in Regulatory T Cells

2004 • 1,198 citations

Dendritic cells as therapeutic vaccines against cancer

2005 • 1,195 citations

Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death

2004 • 972 citations

TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

2005 • 955 citations

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells

2001 • 888 citations

Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism

2005 • 870 citations

CD25+CD4+ Regulatory T Cells Prevent Graft Rejection: CTLA-4- and IL-10-Dependent Immunoregulation of Alloresponses

2002 • 766 citations

CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms

2003 • 748 citations

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

2001 • 658 citations

Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection

2000 • 619 citations

Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4+ Regulatory T Cells

2004 • 618 citations

TGF-β Induces Foxp3 + T-Regulatory Cells from CD4 + CD25 − Precursors

2004 • 527 citations

CD4 ⁺ CD25 ⁺ T regulatory cells control anti-islet CD8 ⁺ T cells through TGF-β–TGF-β receptor interactions in type 1 diabetes

2003 • 439 citations

A New in Vitro Model for the Study of Pancreatic A and B Cells*

1985 • 345 citations

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T-cell subset

2004 • 314 citations

Pancreatic Lymph Node-Derived CD4+CD25+ Treg Cells

2002 • 312 citations

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

2003 • 305 citations

β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

2002 • 289 citations

Response of Human Islets to Isolation Stress and the Effect of Antioxidant Treatment

2004 • 277 citations

Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells

2005 • 273 citations

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

2003 • 261 citations

Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets

2004 • 237 citations

Elevated Vascular Endothelial Growth Factor Production in Islets Improves Islet Graft Vascularization

2004 • 233 citations

CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism

2004 • 210 citations

CD4+ CD25+ CD62+ T-Regulatory Cell Subset Has Optimal Suppressive and Proliferative Potential

2003 • 194 citations

CD4+CD25+ Regulatory T Cells Control Innate Immune Reactivity after Injury

2005 • 185 citations

Anergic T Cells Inhibit the Antigen-Presenting Function of Dendritic Cells

2000 • 173 citations

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells

2004 • 150 citations

An innately interesting decade of research in immunology

2004 • 146 citations

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells

2004 • 141 citations

FTY720 stimulates multidrug transporter– and cysteinyl leukotriene–dependent T cell chemotaxis to lymph nodes

2003 • 125 citations

An Integral Role for Heme Oxygenase-1 and Carbon Monoxide in Maintaining Peripheral Tolerance by CD4+CD25+ Regulatory T Cells

2005 • 120 citations

Interleukin‐6 is a direct mediator of T cell migration

2004 • 108 citations

Blocking the Monocyte Chemoattractant Protein-1/CCR2 Chemokine Pathway Induces Permanent Survival of Islet Allografts through a Programmed Death-1 Ligand-1-Dependent Mechanism

2003 • 108 citations

Reduced Expression of Th1-Associated Chemokine Receptors on Peripheral Blood Lymphocytes at Diagnosis of Type 1 Diabetes

2002 • 89 citations

Early T Cell Response to Allografts Occuring Prior to Alloantigen Priming Up-Regulates Innate-Mediated Inflammation and Graft Necrosis

2004 • 83 citations

Differential Role of CCR2 in Islet and Heart Allograft Rejection: Tissue Specificity of Chemokine/Chemokine Receptor Function In Vivo

2004 • 78 citations

TRAFFICKING OF HOST- AND DONOR-DERIVED DENDRITIC CELLS IN RAT CARDIAC TRANSPLANTATION: ALLOSENSITIZATION IN THE SPLEEN AND HEPATIC NODES1

2001 • 76 citations

CD4+ CD45RB Low-Density Cells from Untreated Mice Prevent Acute Allograft Rejection

1999 • 75 citations

THE EFFECT OF ISLET CELL CULTURE IN VITRO AT 24°C ON GRAFT SURVIVAL AND MHC ANTIGEN EXPRESSION

1990 • 60 citations

Adenovirus Transduction Induces Expression of Multiple Chemokines and Chemokine Receptors in Murine β Cells and Pancreatic Islets

2003 • 52 citations

Differential Expression of Chemokines and Chemokine Receptors in Murine Islet Allografts

2004 • 41 citations

Role of Donor-Derived Monocyte Chemoattractant Protein-1 in Murine Islet Transplantation

2004 • 38 citations

CYTOKINE GENE EXPRESSION IN PANCREATIC ISLET GRAFTS IN THE RAT1

1997 • 36 citations

Viral IL-10 Gene Transfer Inhibits the Expression of Multiple Chemokine and Chemokine Receptor Genes Induced by Inflammatory or Adaptive Immune Stimuli

2003 • 20 citations

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