Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future

Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

2002 • 3,274 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 • 2,781 citations

Defective IL7R expression in T-B+NK+ severe combined immunodeficiency

1998 • 805 citations

Selecting and maintaining a diverse T-cell repertoire

1999 • 712 citations

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

2000 • 679 citations

Assessment of thymic output in adults after haematopoietic stemcell transplantation and prediction of T-cell reconstitution

2000 • 597 citations

Low-Affinity Ligands for the TCR Drive Proliferation of Mature CD8+ T Cells in Lymphopenic Hosts

1999 • 548 citations

Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation

2001 • 436 citations

Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

1996 • 418 citations

Constraints on CD4 Recovery Postchemotherapy in Adults: Thymic Insufficiency and Apoptotic Decline of Expanded Peripheral CD4 Cells

1997 • 334 citations

Late infections after allogeneic bone marrow transplantations: comparison of incidence in related and unrelated donor transplant recipients

1995 • 271 citations

Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

2002 • 268 citations

IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates

2002 • 244 citations

Pathways of T‐cell regeneration in mice and humans: implications for bone marrow transplantation and immmunotherapy

1997 • 235 citations

Analysis of T-cell repopulation after allogeneic bone marrow transplantation: significant differences between recipients of T-cell depleted and unmanipulated grafts

1996 • 231 citations

Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions

2000 • 194 citations

Interleukin-7 restores immunity in athymic T-cell–depleted hosts

2001 • 160 citations

Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone

2002 • 156 citations

Effects of Androgens on T and B Lymphocyte Development

2001 • 151 citations

Abundance of cyclin B1 regulates γ-radiation–induced apoptosis

2000 • 146 citations

Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance.

1990 • 135 citations

Donor lymphocyte infusions for relapse of chronic myeloid leukemia after allogeneic stem cell transplant

1999 • 129 citations

Interleukin 7 worsens graft-versus-host disease

2002 • 125 citations

On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras.

1980 • 118 citations

T cell repopulation from functionally restricted splenic progenitors: 10,000-fold expansion documented by using limiting dilution analyses.

1984 • 105 citations

Incidence, risk factors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation

2003 • 102 citations

Flt3 ligand enhances thymic-dependent and thymic-independent immune reconstitution

2004 • 90 citations

Massive Activation-Induced Cell Death of Alloreactive T Cells With Apoptosis of Bystander Postthymic T Cells Prevents Immune Reconstitution in Mice With Graft-Versus-Host Disease

1999 • 89 citations

Low B-cell and monocyte counts on day 80 are associated with high infection rates between days 100 and 365 after allogeneic marrow transplantation

2000 • 82 citations

Postthymic T‐Cell Development

1986 • 81 citations

Factors affecting antibody levels after allogeneic hematopoietic cell transplantation

2003 • 60 citations

Donor Lymphocyte Infusion for the Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

1998 • 50 citations

Complete sequential regeneration of graft-vs.-host-induced severely dysplastic thymuses. Implications for the pathogenesis of chronic graft-vs.-host disease.

1988 • 38 citations

Late infections following allogeneic bone marrow transplantation: Suggested strategies for prophylaxis

1997 • 28 citations

Massive Activation-Induced Cell Death of Alloreactive T Cells With Apoptosis of Bystander Postthymic T Cells Prevents Immune Reconstitution in Mice With Graft-Versus-Host Disease

1999 • 24 citations

B-cell immunity after allogeneic hematopoietic cell transplantation

2002 • 15 citations