Ligand-Induced Signaling in the Absence of Furin Processing of Notch1

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1998 • 720 citations

Jagged: A mammalian ligand that activates notch1

1995 • 617 citations

Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane

1997 • 615 citations

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

2000 • 556 citations

Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2

1996 • 459 citations

Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors

2000 • 411 citations

The Ins and Outs of Notch Signaling

1997 • 386 citations

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

1996 • 372 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

Nuclear Notch1 signaling and the regulation of dendritic development

2000 • 310 citations

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts

1999 • 304 citations

Cell Surface Presenilin-1 Participates in the γ-Secretase-like Proteolysis of Notch

1999 • 268 citations

Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues.

1981 • 239 citations

Notch signal transduction: a real Rip and more

2000 • 199 citations

Notch Signaling in Vertebrate Development and Disease

1997 • 170 citations

A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex

1998 • 123 citations

An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila

1999 • 120 citations

Functional Analysis of the TAN-1 Gene, a Human Homolog of Drosophila Notch

1994 • 100 citations

Roles for Proteolysis and Trafficking in Notch Maturation and Signal Transduction

1998 • 92 citations

Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless

1997 • 90 citations

Presenilins, Processing of β-Amyloid Precursor Protein, and Notch Signaling

1999 • 66 citations

Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila

1998 • 48 citations