Effector Memory Th1 CD4 T Cells Are Maintained in a Mouse Model of Chronic Malaria

Restoring function in exhausted CD8 T cells during chronic viral infection

2005 • 3,743 citations

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

2006 • 2,521 citations

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

2002 • 1,583 citations

T-cell quality in memory and protection: implications for vaccine design

2008 • 1,499 citations

Immunity to malaria: more questions than answers

2008 • 838 citations

CD27 is required for generation and long-term maintenance of T cell immunity

2000 • 726 citations

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

2009 • 668 citations

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

1997 • 665 citations

Innate immunity to malaria

2004 • 646 citations

Heterogeneity and Cell-Fate Decisions in Effector and Memory CD8+ T Cell Differentiation during Viral Infection

2007 • 567 citations

Protection against a Malaria Challenge by Sporozoite Inoculation

2009 • 556 citations

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

2004 • 489 citations

Immunity to non-cerebral severe malaria is acquired after one or two infections

1999 • 478 citations

Understanding the generation and function of memory T cell subsets

2005 • 459 citations

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

2003 • 454 citations

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes

2007 • 385 citations

Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites

2004 • 348 citations

Activation phenotype, rather than central– or effector–memory phenotype, predicts the recall efficacy of memory CD8+ T cells

2007 • 312 citations

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

2008 • 286 citations

CD4 T Cell-Mediated Protection from Lethal Influenza: Perforin and Antibody-Mediated Mechanisms Give a One-Two Punch

2006 • 277 citations

Functional signatures of protective antiviral T‐cell immunity in human virus infections

2006 • 276 citations

A CD4+ T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease

2004 • 258 citations

Memory CD8 T-cell compartment grows in size with immunological experience

2008 • 220 citations

IL-10, T cell exhaustion and viral persistence

2007 • 218 citations

Modern Flow Cytometry: A Practical Approach

2007 • 203 citations

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

2008 • 200 citations

Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection

2006 • 186 citations

Stepwise Differentiation of CD4 Memory T Cells Defined by Expression of CCR7 and CD27

2005 • 180 citations

Immune Elimination ofLeishmania majorin Mice: Implications for Immune Memory, Vaccination, and Reactivation Disease

2001 • 176 citations

Virus-Specific CD8⁺Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

2002 • 174 citations

A role for B cells in the development of T cell helper function in a malaria infection in mice

1998 • 173 citations

Secondary memory CD8+ T cells are more protective but slower to acquire a central–memory phenotype

2006 • 166 citations

CD4⁺ T‐cell memory: generation and multi‐faceted roles for CD4⁺ T cells in protective immunity to influenza

2006 • 162 citations

Pathology ofPlasmodium chabaudi chabaudiInfection and Mortality in Interleukin-10-Deficient Mice Are Ameliorated by Anti-Tumor Necrosis Factor Alpha and Exacerbated by Anti-Transforming Growth Factor β Antibodies

2003 • 159 citations

A Retrospective Examination of Sporozoite- and Trophozoite-Induced Infections with Plasmodium Falciparum: Development of Parasitologic and Clinical Immunity during Primary Infection

1999 • 143 citations

The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development

2004 • 134 citations

Cutting Edge: Effector Memory CD8+ T Cells Play a Prominent Role in Recall Responses to Secondary Viral Infection in the Lung

2004 • 127 citations

CD4⁺ T cells and B cells are necessary for the transfer of protective immunity to Plasmodium chabaudi chabaudi

1991 • 125 citations

Protracted Protection to Plasmodium berghei Malaria Is Linked to Functionally and Phenotypically Heterogeneous Liver Memory CD8+ T Cells

2003 • 110 citations

Malaria-specific transgenic CD4+ T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance

2005 • 108 citations

Insights into Long-Lasting Protection Induced by RTS,S/AS02A Malaria Vaccine: Further Results from a Phase IIb Trial in Mozambican Children

2009 • 97 citations

Unidirectional development of CD8⁺ central memory T cells into protective Listeria‐specific effector memory T cells

2006 • 91 citations

Deletion ofPlasmodium berghei-specific CD4⁺T cells adoptively transferred into recipient mice after challenge with homologous parasite

1998 • 90 citations

Antigen-Specific T Cells Maintain an Effector Memory Phenotype during Persistent Trypanosoma cruzi Infection

2005 • 79 citations

Malaria‐specific antibody responses and parasite persistence after infection of mice with Plasmodium chabaudi chabaudi

2007 • 70 citations

Persistence and Function of Central and Effector Memory CD4+ T Cells following Infection with a Gastrointestinal Helminth

2006 • 68 citations

Effector CD4 T Cells Are Biochemically Distinct from the Memory Subset: Evidence for Long-Term Persistence of Effectors In Vivo

1999 • 60 citations

Gradual Decline in Malaria-Specific Memory T Cell Responses Leads to Failure to Maintain Long-Term Protective Immunity to Plasmodium chabaudi AS Despite Persistence of B Cell Memory and Circulating Antibody

2008 • 54 citations

Gammaherpesvirus Persistence Alters Key CD8 T-Cell Memory Characteristics and Enhances Antiviral Protection

2006 • 54 citations

CD27low CD4 T Lymphocytes That Accumulate in the Mouse Lungs during Mycobacterial Infection Differentiate from CD27high Precursors In Situ, Produce IFN-γ, and Protect the Host against Tuberculosis Infection

2007 • 46 citations

Stable T-Cell Population Expressing an Effector Cell Surface Phenotype in the Lungs of Mice Chronically Infected with Mycobacterium tuberculosis

2003 • 44 citations

Low CD4(+) T cell responses to the C-terminal region of the malaria merozoite surface protein-1 may be attributed to processing within distinct MHC class II pathways.

2001 • 42 citations

The Dissection of CD8 T Cells During Liver-Stage Infection

2005 • 41 citations

Memory Generation and Maintenance of CD8+ T Cell Function during Viral Persistence

2007 • 38 citations

A retrospective examination of sporozoite-induced and trophozoite-induced infections with Plasmodium ovale: development of parasitologic and clinical immunity during primary infection.

2002 • 35 citations

Different Regions of the Malaria Merozoite Surface Protein 1 ofPlasmodium chabaudiElicit Distinct T-Cell and Antibody Isotype Responses

2001 • 34 citations

Low CD4+ T cell responses to the C-terminal region of the malaria merozoite surface protein-1 may be attributed to processing within distinct MHC class II pathways

2001 • 32 citations

Increasing the CD4+ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality

2008 • 30 citations

Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 T cells

2006 • 29 citations

IFN-γ Mediates the Death of Th1 Cells in a Paracrine Manner

2008 • 26 citations

T cell memory in malaria

2007 • 26 citations