Duration of expression of inducible nitric oxide synthase in glial cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Nitric Oxide: A Physiologic Messenger

1994 • 915 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.

1993 • 782 citations

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

1993 • 671 citations

Calmodulin is a subunit of nitric oxide synthase from macrophages.

1992 • 640 citations

Synthesis of nitric oxide in CNS glial cells

1993 • 627 citations

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

1993 • 623 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action

1992 • 614 citations

Mammalian Nitric Oxide Synthases

1992 • 514 citations

Induction of Nitric Oxide Synthase in Glial Cells

1992 • 501 citations

Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.

1992 • 484 citations

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

1991 • 436 citations

Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes

1991 • 395 citations

Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ

1993 • 355 citations

Inactivation of ribonucleotide reductase by nitric oxide

1991 • 331 citations

Induction of Nitric Oxide Synthase in Rat C6 Glioma Cells

1994 • 157 citations

Norepinephrine Suppresses Inducible Nitric Oxide Synthase Activity in Rat Astroglial Cultures

1993 • 129 citations

Cytokines Regulate L‐Arginine‐Dependent Cyclic GMP Production in Rat Glial Cells

1993 • 124 citations

In vitro interaction between cerebellar astrocytes and granule cells: A putative role for nitric oxide

1992 • 89 citations

Cytokine-Induced Nitric Oxide Generation by Cultured Astrocytoma Cells Involves a Ca2+-Calmodulin-Independent NO-Synthase

1993 • 69 citations

Generation of Astrocyte Cultures from Normal and Neoplastic Central Nervous System

1990 • 40 citations

Immunovascular communication: activation and deactivation of murine endothelial cell nitric oxide synthase by cytokines

1993 • 28 citations

IL1 and TNFα induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway

1993 • 25 citations