An Unusual Eukaryotic Protein Phosphatase Required for Transcription by RNA Polymerase II and CTD Dephosphorylation in S. cerevisiae

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Current protocols in molecular biology

1988 • 7,584 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

THE STRUCTURE AND MECHANISM OF PROTEIN PHOSPHATASES: Insights into Catalysis and Regulation

1998 • 706 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

1999 • 482 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

1994 • 299 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

1987 • 288 citations

A New Class of Phosphotransferases Phosphorylated on an Aspartate Residue in an Amino-terminal DXDX(T/V) Motif

1998 • 255 citations

Growth-related Changes in Phosphorylation of Yeast RNA Polymerase II

1998 • 225 citations

RNA Polymerase II Holoenzymes and Subcomplexes

1998 • 197 citations

TheKIN28Gene is Required both for RNA Polymerase II Mediated Transcription and Phosphorylation of the Rpb1p CTD

1995 • 185 citations

An RNA polymerase I enhancer in Saccharomyces cerevisiae.

1986 • 151 citations

An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae

1997 • 145 citations

FCP1, the RAP74-Interacting Subunit of a Human Protein Phosphatase That Dephosphorylates the Carboxyl-terminal Domain of RNA Polymerase IIO

1998 • 144 citations

Purification and characterization of a phosphatase from HeLa cells which dephosphorylates the C-terminal domain of RNA polymerase II

1994 • 137 citations

The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa.

1992 • 128 citations

Evidence for a mediator cycle at the initiation of transcription

1997 • 126 citations

The Activity of COOH-terminal Domain Phosphatase Is Regulated by a Docking Site on RNA Polymerase II and by the General Transcription Factors IIF and IIB

1995 • 121 citations

Regulation of transcriptional elongation by RNA polymerase II

1995 • 111 citations

Transcription units as RNA processing units

1997 • 110 citations

Broad, but Not Universal, Transcriptional Requirement for yTAFII17, a Histone H3–like TAFII Present in TFIID and SAGA

1998 • 94 citations

Purification and Characterization of an RNA Polymerase II Phosphatase from Yeast

1996 • 76 citations

Sequence Analysis of a 685-kb Genomic Region on Chromosome 3p22-p21.3 That Is Homozygously Deleted in a Lung Carcinoma Cell Line

1997 • 50 citations

Regulation of Carboxyl-terminal Domain Phosphatase by HIV-1 Tat Protein

1998 • 48 citations

Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas

1997 • 43 citations

Regulated synthesis of RNA polymerase II polypeptides in Chinese hamster ovary cell lines.

1979 • 38 citations

Underproduction of the Largest Subunit of RNA Polymerase II Causes Temperature Sensitivity, Slow Growth, and Inositol Auxotrophy in Saccharomyces cerevisiae

1996 • 26 citations