Genealogy of regulation of human sex and adrenal function, prostaglandin action, snapdragon and petunia flower colors, antibiotics, and nitrogen fixation: functional diversity from two ancestral dehydrogenases

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

Symbiotic host-specificity of Rhizobium meliloti is determined by a sulphated and acylated glucosamine oligosaccharide signal

1990 • 1,116 citations

LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR

1988 • 1,047 citations

A Plant Flavone, Luteolin, Induces Expression of Rhizobium meliloti Nodulation Genes

1986 • 967 citations

The complete DNA sequence of vaccinia virus

1990 • 847 citations

MINERALOCORTICOID ACTIVITY OF LIQUORICE: 11-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY COMES OF AGE

1987 • 784 citations

Rhizobium-legume nodulation: Life together in the underground

1989 • 726 citations

Phytoestrogen Interaction with Estrogen Receptors in Human Breast Cancer Cells*

1978 • 605 citations

Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity.

1983 • 515 citations

MINIREVIEW: The Steroid Receptor Superfamily: More Excitement Predicted for the Future

1990 • 489 citations

Cloning and Expression of Rat cDNA Encoding Corticosteroid 11β-Dehydrogenase

1989 • 452 citations

The human oestrogen receptor functions in yeast

1988 • 402 citations

STEROID AND PHYTO-OESTROGEN BINDING TO SHEEP UTERINE RECEPTORS IN VITRO

1972 • 390 citations

Flavonoid activation of nodulation genes in Rhizobium reversed by other compounds present in plants

1986 • 365 citations

Mammalian Glucocorticoid Receptor Derivatives Enhance Transcription in Yeast

1988 • 315 citations

Full Length cDNA Structure and Deduced Amino Acid Sequence of Human β-Hydroxy-5-Ene Steroid Dehydrogenase

1989 • 314 citations

Licorice Inhibits Corticosteroid 1lβ-Dehydrogenase of Rat Kidney and Liver:In Vivoandin VitroStudies*

1989 • 306 citations

Complete amino acid sequence of human placental 17β‐hydroxysteroid dehydrogenase deduced from cDNA

1988 • 298 citations

Characterization of cDNAs for Human Estradiol 17β-Dehydrogenase and Assignment of the Gene to Chromosome 17: Evidence of two mRNA Species with Distinct 5′-Termini in Human Placenta

1989 • 275 citations

Flavonoid synthesis in Petunia hybrida: partial characterization of dihydroflavonol-4-reductase genes

1989 • 265 citations

Clovers secrete specific phenolic compounds which either stimulate or repress nod gene expression in Rhizobium trifolii

1987 • 248 citations

Rhizobium nodulation gene nodD as a determinant of host specificity

1987 • 244 citations

Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture

1968 • 233 citations

Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

1989 • 226 citations

Influence of transposable elements on the structure and function of the A1 gene of Zea mays

1987 • 211 citations

Bioflavonoid interaction with rat uterine type ii binding sites and cell growth inhibition

1988 • 208 citations

Thiostrepton-induced gene expression in Streptomyces lividans

1989 • 199 citations

Characterization of Rat Brain Aldosterone Receptors Reveals High Affinity for Corticosterone

1983 • 188 citations

Nucleotide sequence, transcription and deduced function of a gene involved in polyketide antibiotic synthesis in Streptomyces coelicolor

1988 • 178 citations

Homology between Streptomyces genes coding for synthesis of different polyketides used to clone antibiotic biosynthetic genes

1987 • 164 citations

AFFINITY OF LIQUORICE DERIVATIVES FOR MINERALOCORTICOID AND GLUCOCORTICOID RECEPTORS

1983 • 159 citations

Nucleotide sequence ofRhizobium melilotiRCR2011 genes involved in host specificity of nodulation

1986 • 154 citations

What are antibiotics? Archaic functions for modern activities

1990 • 146 citations

Purification and structural characterization of placental NAD+-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family

1990 • 105 citations

Cloning and sequence analysis of the cDNA for human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.

1990 • 97 citations

The A1 (anthocyanin-1) locus in Zea mays encodes dihydroquercetin reductase

1987 • 91 citations

The symbiotic nitrogen fixation regulatory operon (fixRnifA) ofBradyrhizobium japonicumis expressed aerobically and is subject to a novel,nifA-independent type of activation

1987 • 87 citations

Binding of Glycyrrhetinic Acid to Kidney Mineralocorticoid and Glucocorticoid Receptors¹

1975 • 87 citations

Prokaryotic 20β-hydroxysteroid dehydrogenase is an enzyme of the ‘short-chain, non-metalloenzyme’ alcohol dehydrogenase type

1990 • 85 citations

Extended Region of Nodulation Genes in Rhizobium meliloti 1021. II. Nucleotide Sequence, Transcription Start Sites and Protein Products

1987 • 82 citations

Molecular cloning, cDNA structure and predicted amino acid sequence of bovine 3β‐hydroxy‐5‐ene steroid dehydrogenase/Δ⁵‐Δ⁴ isomerase

1989 • 81 citations

The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast

1990 • 80 citations

Characterization of a unique corticosterone-binding protein in Candida albicans.

1982 • 74 citations

Characterization of an estrogen-binding protein in the yeast Saccharomyces cerevisiae.

1984 • 74 citations

Site-directed mutagenesis of glycine-14 and two "critical" cysteinyl residues in Drosophila alcohol dehydrogenase

1990 • 68 citations

Characterization of an Estrogen-Binding Protein in the YeastCandida albicans*

1989 • 65 citations

Strain-Specific Inhibition of nod Gene Induction in Bradyrhizobium japonicum by Flavonoid Compounds

1990 • 60 citations

THE STEROID RECEPTOR OF ACHLYA AMBISEXUALIS

1985 • 59 citations

Analysis of the steroid receptor of Achlya ambisexualis.

1984 • 56 citations

Effect of carbenoxolone on prostaglandin synthesis and degradation

1976 • 48 citations

The primary structure of alcohol dehydrogenase from Drosophila lebanonensis

1989 • 44 citations

A common ancestor for human placental 17β‐hydroxysteroid dehydrogenase, Streptomyces coelicolor actIII protein, and Drosophila melanogaster alcohol dehydrogenase

1990 • 42 citations

Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity

1984 • 40 citations

SEQUENCES OF INTEREST: Human Placental 17β-Hydroxysteroid Dehydrogenase is Homologous to NodG Protein ofRhizobium meliloti

1989 • 34 citations

The Role of Receptors in Biology and Medicine

1987 • 30 citations

Antheridiol and the oogoniols, steroid hormones which control sexual reproduction in Achlya

1978 • 30 citations

Sequence similarity between Pseudomonas dihydrodiol dehydrogenase, part of the gene cluster that metabolizes polychlorinated biphenyls, and dehydrogenases involved in metabolism of ribitol and glucitol and synthesis of antibiotics and 17 β-oestradiol, testosterone and corticosterone

1990 • 28 citations

Rhizobium sweet-talking

1990 • 20 citations

Characterization of the repetitive DNA elements in the genome of fish lymphocystis disease viruses

1989 • 19 citations

A common ancestor for Candida tropicalis and dehydrogenases that synthesize antibiotics and steroids

1990 • 18 citations

In vitro oxidation of vitamin D metabolites by steroid dehydrogenases

1979 • 6 citations