The CCS1 gene from Saccharomyces cerevisiae which is involved in mitochondrial functions is identified as IRA2 an attenuator of RAS1 and RAS2 gene products

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1987 • 703 citations

Heat shock factor and the heat shock response

1991 • 615 citations

Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.

1987 • 504 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Molecular Cloning of Two Types of GAP Complementary DNA from Human Placenta

1988 • 492 citations

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

1987 • 491 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase

1985 • 429 citations

Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase.

1982 • 351 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein

1990 • 333 citations

IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

1990 • 305 citations

cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae

1988 • 270 citations

IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.

1989 • 251 citations

Genetic map of Saccharomyces cerevisiae, edition 9

1985 • 248 citations

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1985 • 244 citations

Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase.

1987 • 239 citations

Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication

1987 • 238 citations

CDC25 : a Component of the RAS -Adenylate Cyclase Pathway in Saccharomyces cerevisiae

1987 • 235 citations

Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae.

1986 • 232 citations

Molecular mechanisms of transcriptional regulation in yeast

1990 • 224 citations

REGULATORY PROTEINS IN YEAST

1987 • 173 citations

Cloning and Characterization of BCY1, a Locus Encoding a Regulatory Subunit of the Cyclic AMP-Dependent Protein Kinase in Saccharomyces cerevisiae

1987 • 151 citations

Genetic analysis of mammalian GAP expressed in yeast

1989 • 141 citations

A novel method for transformation of intact yeast cells by electroinjection of plasmid DNA

1985 • 141 citations

Genetic map of Saccharomyces cerevisiae, edition 9.

1985 • 137 citations

The sequence of theSaccharomyces cerevisiaegenePH02codes for a regulatory protein with unusual aminoacid composition

1987 • 134 citations

A guanine nucleotide-sensitive adenylate cyclase in the yeast Saccharomyces cerevisiae.

1983 • 124 citations

At least 1400 base pairs of 5′-flanking DNA is required for the correct expression of the HO gene in yeast

1985 • 116 citations

Isolation of the gene encoding adenylate cyclase in Saccharomyces cerevisiae.

1985 • 108 citations

Yeast cdc35 mutants are defective in adenylate cyclase and are allelic with cyr1 mutants while CAS1, a new gene, is involved in the regulation of adenylate cyclase.

1985 • 106 citations

Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae.

1987 • 101 citations

IRA2, a Second Gene of Saccharomyces cerevisiae That Encodes a Protein with a Domain Homologous to Mammalian ras GTPase-Activating Protein

1990 • 83 citations

Regulatory DNA‐binding proteins in yeast: An overview

1990 • 74 citations

Characterization of Saccharomyces Cerevisiae Genes Encoding Subunits of Cyclic AMP-Dependent Protein Kinase

1987 • 73 citations

IRA1, an Inhibitory Regulator of the RAS-Cyclic AMP Pathway in Saccharomyces cerevisiae

1989 • 64 citations

Isolation and nucleotide sequence of a Saccharomyces cerevisiae protein kinase gene suppressing the cell cycle start mutation cdc25.

1987 • 63 citations

Characterization of cyclic AMP-requiring yeast mutants altered in the catalytic subunit of protein kinase.

1984 • 60 citations

Characterization of cyclic AMP-requiring yeast mutants altered in the regulatory subunit of protein kinase.

1982 • 60 citations

Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae

1986 • 50 citations

Cyclic AMP controls the switch between division cycle and resting state programs in response to ammonium availability in Saccharomyces cerevisiae

1987 • 47 citations

Different kinetic properties of the two mutants, RAS2Ile152 and RAS2Val19, that suppress the CDC25 requirement in RAS/adenylate cyclase pathway in Saccharomyces cerevisiae.

1990 • 41 citations

Guanine Nucleotide Activation of, and Competition between, Ras Proteins from Saccharomyces Cerevisiae

1987 • 22 citations

Isolation and genetic study of Triethyltin-resistant mutants of Saccharomyces cerevisiae

1990 • 13 citations

A fragment of Dictyostelium discoideum genomic DNA that complements the URA1 mutation of Saccharomyces cerivisiae.

1982 • 12 citations

Mitochondrial modifications in a single nuclear mutant of Saccharomyces cerevisiae affected in cAMP-dependent protein phosphorylation

1990 • 12 citations

The Cyclic Amp Producing Pathway in Saccharomyces Cerevisiae Involves CDC25 and ras Genes Products

1989 • 5 citations