The molecular architecture of the nuclear pore complex

UCSF Chimera—A visualization system for exploratory research and analysis

2004 • 42,136 citations

The HHpred interactive server for protein homology detection and structure prediction

2005 • 3,542 citations

The Yeast Nuclear Pore Complex

2000 • 1,383 citations

Proteomic analysis of the mammalian nuclear pore complex

2002 • 953 citations

Transport into and out of the Nucleus

2001 • 877 citations

Molecular mechanism of the nuclear protein import cycle

2007 • 862 citations

Nuclear Pore Complex Is Able to Transport Macromolecules with Diameters of ∼39 nm

2002 • 757 citations

Kinetic analysis of translocation through nuclear pore complexes

2001 • 756 citations

A general amphipathic α-helical motif for sensing membrane curvature

2007 • 550 citations

Determining the architectures of macromolecular assemblies

2007 • 531 citations

Molecular model for a complete clathrin lattice from electron cryomicroscopy

2004 • 528 citations

Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

2003 • 494 citations

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

2004 • 493 citations

Dynamic Nuclear Pore Complexes: Life on the Edge

2006 • 479 citations

Architecture and design of the nuclear pore complex

1992 • 452 citations

Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy

1993 • 408 citations

Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture

2004 • 385 citations

Virtual gating and nuclear transport: the hole picture

2003 • 378 citations

Minimal nuclear pore complexes define FG repeat domains essential for transport

2004 • 372 citations

The ins and outs of E-cadherin trafficking

2004 • 356 citations

Three-Dimensional Architecture of the Isolated Yeast Nuclear Pore Complex: Functional and Evolutionary Implications

1998 • 353 citations

Structure of the Sec13/31 COPII coat cage

2006 • 329 citations

A large particle associated with the perimeter of the nuclear pore complex.

1982 • 314 citations

A Novel Complex of Nucleoporins, Which Includes Sec13p and a Sec13p Homolog, Is Essential for Normal Nuclear Pores

1996 • 313 citations

PUSHING THE ENVELOPE: Structure, Function, and Dynamics of the Nuclear Periphery

2005 • 300 citations

Structure and Organization of Coat Proteins in the COPII Cage

2007 • 293 citations

Karyopherin-mediated import of integral inner nuclear membrane proteins

2006 • 270 citations

Simple fold composition and modular architecture of the nuclear pore complex

2006 • 265 citations

Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport

2006 • 257 citations

A new family of yeast nuclear pore complex proteins.

1992 • 256 citations

Cryo-electron Tomography Provides Novel Insights into Nuclear Pore Architecture: Implications for Nucleocytoplasmic Transport

2003 • 242 citations

Nucleoporins as Components of the Nuclear Pore Complex Core Structure and Tpr as the Architectural Element of the Nuclear Basket

2004 • 230 citations

Atomic Structure of Clathrin

1998 • 224 citations

Translocation Through the Nuclear Pore Complex: Selectivity and Speed by Reduction‐of‐Dimensionality

2005 • 207 citations

Karyopherin flexibility in nucleocytoplasmic transport

2006 • 201 citations

Nucleocytoplasmic transport: cargo trafficking across the border

2002 • 188 citations

Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p.

1995 • 184 citations

Binding Dynamics of Isolated Nucleoporin Repeat Regions to Importin-β

2005 • 158 citations

Specific Binding of the Karyopherin Kap121p to a Subunit of the Nuclear Pore Complex Containing Nup53p, Nup59p, and Nup170p

1998 • 155 citations

Vertebrate Nup53 Interacts with the Nuclear Lamina and Is Required for the Assembly of a Nup93-containing Complex

2005 • 133 citations

Yeast genome evolution—the origin of the species

2007 • 129 citations

Structural Basis for the High-affinity Binding of Nucleoporin Nup1p to the Saccharomyces cerevisiae Importin-β Homologue, Kap95p

2005 • 127 citations

Phylogenetic Analysis of Components of the Eukaryotic Vesicle Transport System Reveals a Common Origin of Adaptor Protein Complexes 1, 2, and 3 and the F Subcomplex of the Coatomer COPI

1999 • 121 citations

Life on the Edge

1999 • 120 citations

Efficiency, Selectivity, and Robustness of Nucleocytoplasmic Transport

2007 • 107 citations

Structural plasticity of the nuclear pore complex

1995 • 107 citations

A novel nuclear pore protein Nup82p which specifically binds to a fraction of Nsp1p.

1995 • 102 citations

Yeast nuclear pore complexes have a cytoplasmic ring and internal filaments

2003 • 97 citations

The nuclear pore complex up close

2006 • 95 citations

Functional Characterization of a Nup159p-containing Nuclear Pore Subcomplex

1998 • 90 citations

Nucleoporin Domain Topology is Linked to the Transport Status of the Nuclear Pore Complex

2005 • 77 citations

Importin-α-16 is a translocon-associated protein involved in sorting membrane proteins to the nuclear envelope

2006 • 73 citations

The Nsp1p Carboxy-Terminal Domain Is Organized into Functionally Distinct Coiled-Coil Regions Required for Assembly of Nucleoporin Subcomplexes and Nucleocytoplasmic Transport

2001 • 67 citations

Association of Nuclear Pore FG-repeat Domains to NTF2 Import and Export Complexes

2006 • 66 citations

Nuclear pore complexes exceeding eightfold rotational symmetry

2003 • 58 citations

Nup116p Associates with the Nup82p-Nsp1p-Nup159p Nucleoporin Complex

2000 • 55 citations

Nuclear pore complexes: Round the bend?

2005 • 31 citations

Protease Accessibility Laddering: A Proteomic Tool for Probing Protein Structure

2006 • 31 citations