Dynamic Nuclear Pore Complexes: Life on the Edge

SUMO

2005 • 1,562 citations

The Yeast Nuclear Pore Complex

2000 • 1,383 citations

Proteomic analysis of the mammalian nuclear pore complex

2002 • 953 citations

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

1992 • 825 citations

The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity

2002 • 787 citations

Kinetic analysis of translocation through nuclear pore complexes

2001 • 756 citations

Mechanisms of Receptor‐Mediated Nuclear Import and Nuclear Export

2005 • 686 citations

Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

2003 • 619 citations

Gene gating: a hypothesis.

1985 • 599 citations

Genome-Wide Localization of the Nuclear Transport Machinery Couples Transcriptional Status and Nuclear Organization

2004 • 594 citations

Nucleocytoplasmic transport: taking an inventory

2003 • 514 citations

Dynamics of Single mRNPs in Nuclei of Living Cells

2004 • 498 citations

Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

2003 • 494 citations

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

2004 • 493 citations

Mapping the dynamic organization of the nuclear pore complex inside single living cells

2004 • 470 citations

SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex

1998 • 455 citations

Nuclear Pore Components Are Involved in the Transcriptional Regulation of Dosage Compensation in Drosophila

2006 • 397 citations

Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture

2004 • 385 citations

Minimal nuclear pore complexes define FG repeat domains essential for transport

2004 • 372 citations

Regulation of Nuclear Transport: Central Role in Development and Transformation?

2005 • 352 citations

Chromatin Boundaries in Budding Yeast

2002 • 352 citations

Nuclear Retention of Unspliced mRNAs in Yeast Is Mediated by Perinuclear Mlp1

2004 • 349 citations

Ufd2, a Novel Autoantigen in Scleroderma, Regulates Sister Chromatid Separation

2004 • 319 citations

Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins

1996 • 306 citations

PUSHING THE ENVELOPE: Structure, Function, and Dynamics of the Nuclear Periphery

2005 • 300 citations

Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex

2004 • 286 citations

Pores for thought: nuclear pore complex proteins

1994 • 286 citations

Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p

1999 • 283 citations

Enzymes of the SUMO Modification Pathway Localize to Filaments of the Nuclear Pore Complex

2002 • 279 citations

Simple fold composition and modular architecture of the nuclear pore complex

2006 • 265 citations

The Entire Nup107-160 Complex, Including Three New Members, Is Targeted as One Entity to Kinetochores in Mitosis

2004 • 264 citations

Nup98 Is a Mobile Nucleoporin with Transcription-dependent Dynamics

2002 • 263 citations

A Rae1-Containing Ribonucleoprotein Complex Is Required for Mitotic Spindle Assembly

2005 • 260 citations

Imaging of single-molecule translocation through nuclear pore complexes

2004 • 255 citations

Vesicular Stomatitis Virus Matrix Protein Inhibits Host Cell Gene Expression by Targeting the Nucleoporin Nup98

2000 • 248 citations

Nup-PI: The Nucleopore-Promoter Interaction of Genes in Yeast

2006 • 244 citations

RAE1 Is a Shuttling mRNA Export Factor That Binds to a GLEBS-like NUP98 Motif at the Nuclear Pore Complex through Multiple Domains

1999 • 244 citations

Cryo-electron Tomography Provides Novel Insights into Nuclear Pore Architecture: Implications for Nucleocytoplasmic Transport

2003 • 242 citations

Nuclear transport of single molecules

2005 • 233 citations

The Conserved Transmembrane Nucleoporin NDC1 Is Required for Nuclear Pore Complex Assembly in Vertebrate Cells

2006 • 226 citations

VSV Disrupts the Rae1/mrnp41 mRNA Nuclear Export Pathway

2005 • 219 citations

The DEAD-Box Protein Dbp5p Is Required to Dissociate Mex67p from Exported mRNPs at the Nuclear Rim

2005 • 218 citations

Structural basis for the assembly of a nuclear export complex

2004 • 217 citations

Partial Nuclear Pore Complex Disassembly during Closed Mitosis in Aspergillus nidulans

2004 • 212 citations

Rat8p/Dbp5p is a shuttling transport factor that interacts with Rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1-1 cells

1999 • 209 citations

Translocation Through the Nuclear Pore Complex: Selectivity and Speed by Reduction‐of‐Dimensionality

2005 • 207 citations

Kinetochore structure and function

2005 • 201 citations

The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import

2002 • 199 citations

Developmentally induced changes in transcriptional program alter spatial organization across chromosomes

2005 • 196 citations

Proteomic Analysis of Nucleoporin Interacting Proteins

2001 • 188 citations

The Rae1–Nup98 complex prevents aneuploidy by inhibiting securin degradation

2005 • 181 citations

Caenorhabditis elegansNucleoporins Nup93 and Nup205 Determine the Limit of Nuclear Pore Complex Size Exclusion In Vivo

2003 • 181 citations

Inhibition of Ran Guanosine Triphosphatase-Dependent Nuclear Transport by the Matrix Protein of Vesicular Stomatitis Virus

1997 • 175 citations

Modularity within the architecture of the nuclear pore complex

2005 • 162 citations

Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes

2003 • 157 citations

Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling

2005 • 155 citations

Cell Cycle Regulated Transport Controlled by Alterations in the Nuclear Pore Complex

2003 • 146 citations

Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex

2002 • 139 citations

The N-Terminal Domain of Nup159 Forms a β-Propeller that Functions in mRNA Export by Tethering the Helicase Dbp5 to the Nuclear Pore

2004 • 139 citations

Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality

2004 • 138 citations

The Three-Dimensional Structure of the Autoproteolytic, Nuclear Pore-Targeting Domain of the Human Nucleoporin Nup98

2002 • 127 citations

Complex Formation among the RNA Export Proteins Nup98, Rae1/Gle2, and TAP

2003 • 127 citations

Accelerating the Rate of Disassembly of Karyopherin·Cargo Complexes

2002 • 125 citations

Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins

2002 • 122 citations

The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control

2005 • 116 citations

SUMO Modification of Heterogeneous Nuclear Ribonucleoproteins

2004 • 111 citations

Yeast Nucleoporins Involved in Passive Nuclear Envelope Permeability

2000 • 109 citations

Npap60/Nup50 Is a Tri-Stable Switch that Stimulates Importin-α:β-Mediated Nuclear Protein Import

2002 • 108 citations

Structural plasticity of the nuclear pore complex

1995 • 107 citations

members only encodes a Drosophila nucleoporin required for Rel protein import and immune response activation

2000 • 93 citations

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans

2003 • 82 citations

Inhibition of nucleo-cytoplasmic trafficking by RNA viruses: targeting the nuclear pore complex

2003 • 81 citations

The Nucleoporin Nup98 Is a Site for GDP/GTP Exchange on Ran and Termination of Karyopherin β2-mediated Nuclear Import

2000 • 78 citations

Nucleoporin Domain Topology is Linked to the Transport Status of the Nuclear Pore Complex

2005 • 77 citations

The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo

2004 • 74 citations

Analysis of nucleo-cytoplasmic transport in a thermosensitive mutant of nuclear pore protein NSP1.

1993 • 58 citations

Caspases Target Only Two Architectural Components within the Core Structure of the Nuclear Pore Complex

2005 • 55 citations

cDNA Cloning and Characterization ofNpap60:A Novel Rat Nuclear Pore-Associated Protein with an Unusual Subcellular Localization during Male Germ Cell Differentiation

1997 • 45 citations

Characterization and potential function of a novel testis‐specific nucleoporin BS‐63

2001 • 43 citations

5 Ribosomes and the RNA World

1993 • 2 citations