Architecture and design of the nuclear pore complex

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

Nuclear envelope permeability

1975 • 808 citations

Structure of the junction between communicating cells

1980 • 697 citations

Identification and characterization of a nuclear pore complex protein

1986 • 610 citations

Functional Organization Of The Nuclear Envelope

1988 • 593 citations

How proteins enter the nucleus

1991 • 555 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.

1987 • 533 citations

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.

1987 • 510 citations

Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components.

1990 • 510 citations

Three‐Dimensional reconstruction of single particles from random and nonrandom tilt series

1988 • 497 citations

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

1987 • 428 citations

A modified procedure for the isolation of a pore complex-lamina fraction from rat liver nuclei.

1976 • 423 citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1991 • 391 citations

Computer Averaging of Electron Micrographs of 40 S Ribosomal Subunits

1981 • 377 citations

Digital image processing: The semper system

1979 • 355 citations

The nuclear envelope and the architecture of the nuclear periphery.

1981 • 320 citations

A large particle associated with the perimeter of the nuclear pore complex.

1982 • 314 citations

Injected nuclei in frog oocytes: fate, enlargement, and chromatin dispersal

1976 • 305 citations

SPIDER—A modular software system for electron image processing

1981 • 287 citations

The effects of variations in the number and sequence of targeting signals on nuclear uptake.

1988 • 273 citations

A complex of nuclear pore proteins required for pore function.

1991 • 231 citations

Reconstitution of biochemically altered nuclear pores: Transport can be eliminated and restored

1990 • 228 citations

Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.

1989 • 228 citations

A major glycoprotein of the nuclear pore complex is a membrane-spanning polypeptide with a large lumenal domain and a small cytoplasmic tail.

1990 • 222 citations

Harmonic analysis of electron microscope images with rotational symmetry

1971 • 218 citations

Protein import through the nuclear pore complex is a multistep process.

1989 • 208 citations

IMAGIC: A fast, flexible and friendly image analysis software system

1981 • 207 citations

Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy.

1989 • 193 citations

Characteristic views of E. coli and B. stearothermophilus 30S ribosomal subunits in the electron microscope.

1985 • 177 citations

Spider—A modular software system for electron image processing

1981 • 174 citations

The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.

1991 • 173 citations

The structure of viruses of the papilloma-polyoma type

1965 • 160 citations

Visualization of transport-related configurations of the nuclear pore transporter

1990 • 156 citations

Structures and Functions of the Nuclear Envelope

1974 • 142 citations

The ultrastructure of the nuclear envelope of amphibian oocytes: a reinvestigation I. The mature oocyte

1970 • 141 citations

The ultrastructure of the nuclear envelope of amphibian oocytes: a reinvestigation

1970 • 124 citations

A monoclonal antibody against a family of nuclear pore proteins (nucleoporins): O-linked N-acetylglucosamine is part of the immunodeterminant.

1987 • 123 citations

Classification of macromolecular assemblies studied as ‘single particles’

1990 • 113 citations

Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals.

1989 • 101 citations

Yeast proteins that recognize nuclear localization sequences.

1989 • 99 citations

Structure and Function of the Nuclear Envelope and Related Cytomembranes

1973 • 71 citations

Structure of viruses of the papilloma-polyoma type

1965 • 63 citations

Identification of a human protein that interacts with nuclear localization signals.

1989 • 62 citations

The structure and interactions of components of nuclear envelopes from Xenopus oocyte germinal vesicles observed by heavy metal shadowing

1988 • 47 citations

EM visualization of nucleocytoplasmic transport processes

1990 • 42 citations

Nucleocytoplasmic Transport

1986 • 42 citations

A protein recognized by antibodies to Asp-Asp-Asp-Glu-Asp shows specific binding activity to heterogeneous nuclear transport signals.

1990 • 38 citations

Structural studies of human ?2-macroglobulin: Concordance between projected views obtained by negative-stain and cryoelectron microscopy*1

1991 • 28 citations

A Structural Model for the Nuclear Pore Complex

1986 • 17 citations

Identification and characterization of nuclear location signal-binding proteins in nuclear envelopes

1991 • 8 citations