Molecular characterization of a human brain adenosine A2 receptor

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

1970 • 860 citations

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.

1986 • 821 citations

How does adenosine inhibit transmitter release?

1988 • 649 citations

Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor Family

1989 • 647 citations

Two distinct adenosine-sensitive sites on adenylate cyclase.

1977 • 574 citations

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

1989 • 537 citations

Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine

1982 • 417 citations

Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680

1989 • 344 citations

Purine Receptors in Mammalian Tissues: Pharmacology and Functional Significance

1987 • 302 citations

RDC8 codes for an adenosine A2 receptor with physiological constitutive activity

1990 • 270 citations

Structure/function relationship of proteins belonging to the family of receptors coupled to GTP‐binding proteins

1991 • 241 citations

Cloning and expression of an A1 adenosine receptor from rat brain.

1991 • 235 citations

Adenosine A2 receptors: Selective localization in the human basal ganglia and alterations with disease

1991 • 198 citations

The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.

1991 • 191 citations

Molecular cloning of a novel putative G‐protein coupled receptor expressed during rat spermiogenesis

1991 • 186 citations

Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum.

1990 • 167 citations

Agonist and antagonist affinities for inhibitory adenosine receptors are reciprocally affected by 5'-guanylylimidodiphosphate or N-ethylmaleimide.

1983 • 119 citations

[3H]5?-N-ethylcarboxamide adenosine binds to both Ra and Ri adenosine receptors in rat striatum

1984 • 110 citations

Binding of the Adenosine A₂ Receptor Ligand [³H]CGS 21680 to Human and Rat Brain: Evidence for Multiple Affinity Sites

1990 • 98 citations

Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain

1989 • 94 citations

Adenosine-sensitive adenylate cyclase in rat brain homogenates: kinetic characteristics, specificity, topographical, subcellular and cellular distribution.

1979 • 78 citations

The distribution of adenosine A1 receptors and 5′‐nucleotidase in the hippocampal formation of several mammalian species

1986 • 71 citations

Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences

1992 • 49 citations

Structural heterogeneity of membrane receptors and GTP‐binding proteins and its functional consequences for signal transduction

1991 • 44 citations

[3H]Cyclohexyladenosine binding in rat brain: A pharmacological analysis using quantitative autoradiography

1986 • 25 citations

Identification of cyclic AMP as the response regulator for neurosecretory potentiation: a memory model system.

1991 • 22 citations