Mechanisms of oligodendrocyte commitment in the vertebrate CNS

Cell Death During Development of the Nervous System

1991 • 3,033 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

Astrocytes induce blood–brain barrier properties in endothelial cells

1987 • 1,593 citations

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes

1992 • 1,514 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

Neuron‐glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electonmicroscopic study in Macacus rhesus

1971 • 1,334 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: An immunocytological study in the central nervous system

1981 • 1,131 citations

The Fine Structure of the Nervous System

1991 • 1,058 citations

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1995 • 886 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity

1996 • 866 citations

The oligodendrocyte and its many cellular processes

1993 • 837 citations

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1988 • 833 citations

Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture

1978 • 813 citations

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

1988 • 756 citations

Glial Cell Diversification in the Rat Optic Nerve

1989 • 725 citations

Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain

1993 • 714 citations

Multiple extracellular signals are required for long-term oligodendrocyte survival

1993 • 707 citations

Bone Morphogenetic Proteins Promote Astroglial Lineage Commitment by Mammalian Subventricular Zone Progenitor Cells

1996 • 681 citations

FGF modulates the PDGF-driven pathway of oligodendrocyte development

1990 • 586 citations

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

1994 • 585 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Glial cells and the central myelin sheath.

1968 • 530 citations

A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage

1993 • 497 citations

Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

1998 • 484 citations

Identification of an adult-specific glial progenitor cell

1989 • 476 citations

Evidence for migration of oligodendrocyte–type-2 astrocyte progenitor cells into the developing rat optic nerve

1987 • 471 citations

FGF2 Concentration Regulates the Generation of Neurons and Glia from Multipotent Cortical Stem Cells

1997 • 455 citations

PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage

1992 • 435 citations

Insulin‐like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro

1988 • 361 citations

A crucial role for neurotrophin-3 in oligodendrocyte development

1994 • 353 citations

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

1988 • 343 citations

Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube.

1997 • 323 citations

Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression

1995 • 296 citations

Multiple Restricted Origin of Oligodendrocytes

1998 • 295 citations

Determination of Neuroepithelial Cell Fate: Induction of the Oligodendrocyte Lineage by Ventral Midline Cells and Sonic Hedgehog

1996 • 279 citations

The generation of neurons and oligodendrocytes from a common precursor cell

1991 • 274 citations

The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated

1993 • 273 citations

Two proliferative stages of the oligodendrocyte lineage (A2B5+O4- and O4+GaIC-) under different mitogenic control

1990 • 270 citations

Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord

1991 • 268 citations

Sonic hedgehog signaling is required during the appearance of spinal cord oligodendrocyte precursors

1999 • 266 citations

Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts

1993 • 259 citations

Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

1988 • 249 citations

Unwrapping the genes of myelin

1988 • 246 citations

Effect of the notochord on the differentiation of a floor plate area in the neural tube of the chick embryo

1988 • 246 citations

Embryonic expression of myelin genes: Evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube

1994 • 241 citations

Molecular Biology of Myelin Proteins from the Central Nervous System

1988 • 238 citations

Interaction between NG2 proteoglycan and PDGF ?-receptor on O2A progenitor cells is required for optimal response to PDGF

1996 • 236 citations

Neuregulins in Development

1996 • 229 citations

The in vitro differentiation of a bipotential glial progenitor cell.

1984 • 227 citations

Oligodendrocyte origins

1996 • 222 citations

A developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation

1994 • 209 citations

Oligodendrocyte precursors originate at the ventral ventricular zone dorsal to the ventral midline region in the embryonic rat spinal cord

1993 • 201 citations

The Macroglial Cells of the Rat Optic Nerve

1989 • 192 citations

Proligodendroblast Antigen (POA), a Developmental Antigen Expressed by A007/O4‐Positive Oligodendrocyte Progenitors Prior to the Appearance of Sulfatide and Galactocerebroside

1992 • 185 citations

Early development and dispersal of oligodendrocyte precursors in the embryonic chick spinal cord

1995 • 174 citations

Axonal Neuregulin Signals Cells of the Oligodendrocyte Lineage through Activation of HER4 and Schwann Cells through HER2 and HER3

1997 • 172 citations

Glial Cell Mitogens bFGF and PDGF Differentially Regulate Development of O4+GalC- Oligodendrocyte Progenitors

1993 • 170 citations

Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth’s shorttail mutation

1991 • 168 citations

Focal Ventricular Origin and Migration of Oligodendrocyte Precursors into the Chick Optic Nerve

1997 • 168 citations

Failure of spinal cord oligodendrocyte development in mice lacking neuregulin

1999 • 165 citations

Is programmed cell death required for neural tube closure?

1997 • 162 citations

Regulation of FGF Receptors in the Oligodendrocyte Lineage

1996 • 160 citations

Origins of Spinal Cord Oligodendrocytes: Possible Developmental and Evolutionary Relationships with Motor Neurons

1997 • 145 citations

Induction of oligodendrocyte progenitors in the trunk neural tube by ventralizing signals: effects of notochord and floor plate grafts, and of sonic hedgehog

1996 • 141 citations

Requirement of polysialic acid for the migration of the O-2A glial progenitor cell from neurohypophyseal explants

1994 • 139 citations

The origin of remyelinating cells in the adult central nervous system: The role of the mature oligodendrocyte

1991 • 132 citations

Programmed cell death during the earliest stages of spinal cord development in the chick embryo: A possible means of early phenotypic selection

1994 • 126 citations

Evidence for the Existence of at Least Two Timing Mechanisms That Contribute to Oligodendrocyte Generationin Vitro

1996 • 114 citations

The Origin of Spinal Cord Oligodendrocytes Is Dependent on Local Influences from the Notochord

1996 • 113 citations

Pax6 Influences the Time and Site of Origin of Glial Precursors in the Ventral Neural Tube

1998 • 106 citations

Effect of the notochord on proliferation and differentiation in the neural tube of the chick embryo

1989 • 103 citations

Dynamic Synapses in the Cortex

1997 • 101 citations

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism

1997 • 101 citations

Floor plate-derived signals and the control of neural cell pattern in vertebrates.

1990 • 100 citations

Tenascin-C Inhibits Oligodendrocyte Precursor Cell Migration by both Adhesion-Dependent and Adhesion-Independent Mechanisms

1996 • 96 citations

Coexistence of perinatal and adult forms of a glial progenitor cell during development of the rat optic nerve

1990 • 94 citations

A novel type of programmed neuronal death in the cervical spinal cord of the chick embryo.

1996 • 90 citations

A Novel Type of Programmed Neuronal Death in the Cervical Spinal Cord of the Chick Embryo

1996 • 88 citations

Distribution and differentiation of A2B5⁺ glial precursors in the developing rat spinal cord

1994 • 87 citations

Oligodendroblasts Distinguished from O-2A Glial Progenitors by Surface Phenotype (O4+GalC-) and Response to Cytokines Using Signal Transducer LIFRβ

1995 • 78 citations

Analysis of the cell-cell interactions that control type-2 astrocyte development in vitro

1990 • 75 citations

Environmental Enhancement of Growth Factor-Mediated Oligodendrocyte Precursor Proliferation

1996 • 53 citations

Early development of the oligodendrocyte in the embryonic chick metencephalon

1997 • 36 citations

Development of Glial Cytoarchitecture in the Frog Spinal Cord

1995 • 20 citations

Molecular biology of myelination

1995 • 17 citations

Notochord is essential for oligodendrocyte development inXenopus spinal cord

1997 • 16 citations