Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Pharmacology ofCurcuma longa

1991 • 1,684 citations

Signal transduction by tumor necrosis factor and its relatives

2001 • 1,623 citations

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

1995 • 1,352 citations

Mechanisms of Apoptosis

2000 • 1,249 citations

Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.

1988 • 735 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound.

1995 • 682 citations

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

2003 • 678 citations

Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.

1991 • 571 citations

Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.

1994 • 550 citations

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

2001 • 434 citations

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

1998 • 399 citations

Curcumin Induces Apoptosis in Human Melanoma Cells through a Fas Receptor/Caspase-8 Pathway Independent of p53

2001 • 379 citations

Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation.

1986 • 304 citations

Inhibition of tumor necrosis factor by curcumin, a phytochemical

1995 • 302 citations

Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice

1992 • 299 citations

Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene

1992 • 266 citations

Toxicity studies on turmeric (Curcuma longa): acute toxicity studies in rats, guineapigs & monkeys.

1980 • 201 citations

Curcumin Suppresses Activation of NF-κB and AP-1 Induced by Phorbol Ester in Cultured Human Promyelocytic Leukemia Cells

2002 • 197 citations

Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of beta-carotene.

1994 • 179 citations

The Dietary Pigment Curcumin Reduces Endothelial Tissue Factor Gene Expression by Inhibiting Binding of AP-1 to the DNA and Activation of NF-κB

1997 • 165 citations

Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins.

1989 • 164 citations

Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents.

1990 • 148 citations

Tumor Necrosis Factor Increases Hepatocellular Glutathione by Transcriptional Regulation of the Heavy Subunit Chain of γ-Glutamylcysteine Synthetase

1997 • 145 citations

Bcr–Abl variants: biological and clinical aspects

2002 • 133 citations

A Novel Apoptosis-like Pathway, Independent of Mitochondria and Caspases, Induced by Curcumin in Human Lymphoblastoid T (Jurkat) Cells

1999 • 132 citations

Protein-tyrosine Phosphatase Inhibitors Block Tumor Necrosis Factor-dependent Activation of the Nuclear Transcription Factor NF-kB

1995 • 123 citations

The organization of the human GSTP1-1 gene promoter and its response to retinoic acid and cellular redox status

1996 • 113 citations

Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones

1986 • 109 citations

Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation

2002 • 105 citations

Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients.

1990 • 99 citations

Expression of glutathione transferase pi as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia.

1992 • 97 citations

Rapid test forin vivostability and DNA binding of mutated octamer binding proteins with ‘mini extracts’, prepared from a transfected cells

1989 • 91 citations

Glutathione S-transferase PI (GST-pi) Class Expression by Immunohistochemistry in Benign and Malignant Prostate Tissue

1997 • 91 citations

Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine‐induced hamster oral carcinogenesis

1992 • 85 citations

Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes

1990 • 77 citations

Involvement of Jun and Fos proteins in regulating transcriptional activation of the human pi class glutathione S-transferase gene in multidrug-resistant MCF7 breast cancer cells.

1994 • 73 citations

P-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukaemia

1994 • 66 citations

Regulation of human glutathione S-transferase π gene transcription: influence of 5′-flanking sequences and trans-mactivating factors which recognize AP-1-binding sites

1990 • 63 citations

Drug resistance to cis-diamminedichloroplatinum(II) in chinese hamster ovary cell lines transfected with glutathione S-transferase pi gene

1990 • 62 citations

Glutathione S Transferase Pi Is a Powerful Indicator in Chemotherapy of Human Lung Squamous-Cell Carcinoma

1995 • 54 citations

Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin

1998 • 54 citations

Prognostic Significance of the Expressions of Metallothionein, Glutathione-S-Transferase-π, and P-Glycoprotein in Curatively Resected Gastric Cancer

1997 • 54 citations

Expression of MDR1 and GST-π in human soft tissue sarcomas: Relation to drug resistance and biological aggressiveness

1992 • 52 citations

The effect of curcumin on glutathione-linked enzymes in K562 human leukemia cells

1999 • 49 citations

Messenger RNA expression of resistance proteins and related factors in human ovarian carcinoma cell lines resistant to doxorubicin, taxol and cisplatin

1997 • 38 citations

Glutathione S-transferases and cancer (Review)

1997 • 25 citations

Phorbol ester responsiveness of the glutathione S-transferase P1 gene promoter involves an inducible c-jun binding in human K562 leukemia cells

2001 • 24 citations