Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

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Activators and Target Genes of Rel/NF-кB Transcription Factors

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

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Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

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Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

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NF-κB as a Therapeutic Target in Multiple Myeloma

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Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity.

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Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound.

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Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex

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Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity

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Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer.

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Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1

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Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

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Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

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Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

2001 • 385 citations

Curcumin Induces Apoptosis in Human Melanoma Cells through a Fas Receptor/Caspase-8 Pathway Independent of p53

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Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient.

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Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IκB kinase and NFκB activation in macrophages

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Constitutive Activation of NF-κB Causes Resistance to Apoptosis in Human Cutaneous T Cell Lymphoma HuT-78 Cells

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Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells

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Curcuminoids Inhibit the Angiogenic Response Stimulated by Fibroblast Growth Factor-2, Including Expression of Matrix Metalloproteinase Gelatinase B

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Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis

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Curcumin (Diferuloylmethane) Inhibition of Tumor Necrosis Factor (TNF)-Mediated Adhesion of Monocytes to Endothelial Cells by Suppression of Cell Surface Expression of Adhesion Molecules and of Nuclear Factor-κB Activation

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Nuclear Factor-κB Activation: A Question of Life or Death

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IκB kinase: Beginning, not the end

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Role of NF-κB in the Rescue of Multiple Myeloma Cells From Glucocorticoid-Induced Apoptosis by Bcl-2

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Leflunomide Suppresses TNF-Induced Cellular Responses: Effects on NF-κB, Activator Protein-1, c-Jun N-Terminal Protein Kinase, and Apoptosis

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The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G₁ Transition

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Proteasome inhibition in cancer: Development of PS-341

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Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266

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[53] Assay for redox-sensitive transcription factor

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Analysis of expression of nuclear factor κB (NF‐κB) in multiple myeloma: downregulation of NF‐κB induces apoptosis

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Characterization of adhesion molecules on human myeloma cell lines

1992 • 150 citations

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1992 • 137 citations

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A mechanism of resistance to glucocorticoids in multiple myeloma: transient expression of a truncated glucocorticoid receptor mRNA

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Diagnosis and management of multiple myeloma

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Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells

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A mechanism of resistance to glucocorticoids in multiple myeloma: transient expression of a truncated glucocorticoid receptor mRNA

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Characterization of a novel myeloma cell line, MM.1.

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