Diurnal variation in excitation of dorsal horn units by naloxone in the spinal cat suggests a circulating opioid factor

β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland

1977 • 1,426 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla

1977 • 863 citations

Brainstem Control of Spinal Pain-Transmission Neurons

1978 • 820 citations

Central nervous system mechanisms of analgesia

1976 • 710 citations

Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques

1977 • 656 citations

Effects of substance P on functionally identified units in cat spinal cord

1976 • 655 citations

Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section

1976 • 642 citations

Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.

1976 • 639 citations

The puzzle of pain

1973 • 582 citations

C fragment of lipotropin has a high affinity for brain opiate receptors

1976 • 488 citations

Endogenous and Exogenous Opiate Agonists and Antagonists

1980 • 442 citations

Hyperalgesia Induced by Naloxone Follows Diurnal Rhythm in Responsivity to Painful Stimuli

1977 • 373 citations

Dose-dependent reductions by naloxone of analgesia induced by cold-water stress

1978 • 312 citations

Reversal of morphine and stimulus-produced analgesia by subtotal spinal cord lesions

1977 • 303 citations

Facilitation de r�actions nociceptives par la naloxone chez la souris et chez le rat

1974 • 295 citations

Naloxone alters pain perception and somatosensory evoked potentials in normal subjects

1977 • 287 citations

The narcotic antagonist naloxone enhances clinical pain

1978 • 257 citations

Entry of Opioid Peptides into the Central Nervous System

1980 • 247 citations

β-ENDORPHIN AND ADRENOCORTICOTROPIN ARE SECRETED CONCOMITANTLY BY THE PITUITARY GLAND

1978 • 242 citations

Nitrous Oxide "Analgesia": Resemblance to Opiate Action

1976 • 213 citations

Nitrous oxide analgesia: reversal by naloxone and development of tolerance.

1977 • 195 citations

Lack of effect of naloxone on pain perception in humans

1976 • 191 citations

Characteristics and functions of opioids

1980 • 183 citations

Stress-produced analgesia and morphine-produced analgesia: Lack of cross-tolerance

1978 • 170 citations

Lipotropin: Precursor to two biologically active peptides

1976 • 160 citations

An Analog of Enkephalin Having Prolonged Opiate-Like Effects in Vivo

1977 • 159 citations

Differential effects of spinal cord lesions on narcotic and non-narcotic supression of nociceptive reflexes: Further evidence for the physiologic multiplicity of pain modulation

1978 • 156 citations

Effects of naloxone on experimentally induced ischemic pain and on mood in human subjects.

1977 • 152 citations

Effects of Morphine and Naloxone on Dorsal Horn Neurones in the Cat

1974 • 143 citations

On the role of endogenous opioid peptides: Failure of naloxone to influence shock escape threshold in the rat

1976 • 137 citations

Naloxone decreases diurnal variation in pain sensitivity and somatosensory evoked potentials

1978 • 116 citations

Drug interaction in the field of analgesic drugs.

1965 • 106 citations

The influence of naloxone on the C fiber response of dorsal horn neurons and their inhibitory control by raphe magnus stimulation

1979 • 100 citations

Naloxone reversal of morphine analgesia but failure to alter reactivity to pain in the formalin test

1978 • 98 citations

Drug Interaction in the Field of Analgesic Drugs

1965 • 90 citations

Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.

1976 • 82 citations

The Cutaneous Pricking Pain Threshold in Old Age

1970 • 77 citations

Antinociceptive effects of intrathecally administered human β-endorphin in the rat and cat

1978 • 72 citations

Naloxone excites nociceptive units in the lumbar dorsal horn of the spinal cat

1979 • 68 citations

Effect of naloxone on the behaviour of rats exposed to a novel environment

1979 • 67 citations

2-Deoxy-D-glucose analgesia: Influences of opiate and non-opiate factors

1979 • 61 citations

Effect of opiate receptor blockade on pain sensitivity in the rat

1977 • 59 citations

Naloxone enhancement of acetic acid-induced writhing in rats

1977 • 51 citations

Electric shock titration: effects of morphine, metadone, pentazocine, naloriphine, naloxone, diazepam and amphetamine.

1977 • 37 citations

Diurnal variation in sensory and pain thresholds correlated with mood states.

1978 • 35 citations

Primary afferent depolarisation of tooth pulp afferents is not affected by naloxone

1978 • 26 citations

Actions of narcotic analgesics and antagonists on spinal units responding to natural stimulation in the cat

1979 • 25 citations

Studies on the cutaneous pricking pain threshold in man. Circadian and circatrigintan changes.

1970 • 24 citations

Endorphin activity in anterior, intermediate, and posterior pituitary

1976 • 15 citations

Diurnal changes in serotonin content of frontal pole and pain sensitivity in the rat

1978 • 14 citations

Studies on the Cutaneous Pricking Pain Threshold in Man. Circadian and Circatrigintan Changes

1972 • 12 citations

SWIM-STRESS INDUCED ANALGESIA: STUDY OF TOLERANCE AND CROSS TOLERANCE TO MORPHINE

1978 • 8 citations

NALOXONE EXCITATION OF SPINAL DORSAL HORN UNITS SHOWS DIURNAL VARIATION

1980 • 4 citations