Naloxone excites nociceptive units in the lumbar dorsal horn of the spinal cat

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat

1976 • 767 citations

Antagonism of acupuncture analgesia in man by the narcotic antagonist naloxone

1977 • 742 citations

Pain Relief by Electrical Stimulation of the Central Gray Matter in Humans and Its Reversal by Naloxone

1977 • 740 citations

Antagonism of Stimulation-Produced Analgesia by Naloxone, a Narcotic Antagonist

1976 • 664 citations

Effects of substance P on functionally identified units in cat spinal cord

1976 • 655 citations

Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section

1976 • 642 citations

Statistical methods in research and production

1950 • 513 citations

Neurons that subserve the sensory-discriminative aspects of pain

1977 • 429 citations

An endogenous morphine-like factor in mammalian brain

1975 • 393 citations

Naloxone as a GABA antagonist: Evidence from iontophoretic, receptor binding and convulsant studies

1978 • 330 citations

The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat

1976 • 321 citations

Search for an Endogenous Ligand for the Opiate Receptor

1975 • 315 citations

Narcotic Analgesics and Antagonists

1971 • 309 citations

Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.

1977 • 299 citations

Facilitation de r�actions nociceptives par la naloxone chez la souris et chez le rat

1974 • 295 citations

Isolation

1975 • 286 citations

Naloxone reversal of analgesia produced by brain stimulation in the human

1976 • 261 citations

Purification and properties of enkephalin — The possible endogenous ligand for the morphine receptor

1975 • 240 citations

Opiate antagonist, naloxone, strongly reduces analgesia induced by stimulation of a raphe nucleus (centralis inferior)

1977 • 214 citations

Acupuncture reduces electrophysiological and behavioral responses to noxious stimuli: Pituitary is implicated

1977 • 212 citations

Lack of effect of naloxone on pain perception in humans

1976 • 191 citations

Effects of naloxone on experimentally induced ischemic pain and on mood in human subjects.

1977 • 152 citations

Effects of Morphine and Naloxone on Dorsal Horn Neurones in the Cat

1974 • 143 citations

Effects of microiontophoretically applied methionine-enkephalin on single neurones in rat brainstem

1976 • 135 citations

The direct and specific opiate-like effect of Met5-enkephalin and analogues on the spinal cord

1977 • 90 citations

Enhancement of reflexes by naloxone in spinal cats

1976 • 86 citations

The effect of the narcotic antagonists naloxone, naltrexone and nalorphine on spinal cord c-fiber reflexes evoked by electrical stimulation or radiant heat

1977 • 74 citations

The effect of naloxone on the excitation of dorsal horn neurones of the cat by noxious and non-noxious cutaneous stimuli

1977 • 62 citations

Effect of opiate receptor blockade on pain sensitivity in the rat

1977 • 59 citations

Narcotic Antagonists (Advances in Biochemical Psycho-pharmacology 8)

1975 • 48 citations

Transmitters and identified neurons in the mammalian central nervous system

1975 • 44 citations

Selective opiate depression of sensory-evoked synaptic networks in dorsal horn regions of spinal cord cultures

1977 • 38 citations

Pain relief by electrical stimulation of the central grey matter in humans and its reversal by naloxone

1979 • 26 citations

Morphine Excitation in the Cerebral Cortex

1975 • 24 citations

A method for site selectivity analysis applied to opiate receptors

1976 • 22 citations

Narcotic Antagonists: The Search Accelerates

1972 • 16 citations