Hyperalgesia Induced by Naloxone Follows Diurnal Rhythm in Responsivity to Painful Stimuli

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

1975 • 981 citations

Antagonism of Stimulation-Produced Analgesia by Naloxone, a Narcotic Antagonist

1976 • 664 citations

Stress-induced parallel changes in central opioid levels and pain responsiveness in the rat

1977 • 560 citations

Opioid Peptides Endorphins in Pituitary and Brain

1976 • 518 citations

Human Prolactin: 24-Hour Pattern with Increased Release during Sleep

1972 • 458 citations

Search for an Endogenous Ligand for the Opiate Receptor

1975 • 315 citations

Facilitation de r�actions nociceptives par la naloxone chez la souris et chez le rat

1974 • 295 citations

Enkephalin pentapeptides — A review of current evidence for a physiological role in vertebrate neurotransmission

1977 • 269 citations

The regional distribution of a morphine-like factor enkephalin in monkey brain

1976 • 266 citations

β-Endorphin in vitro inhibition of striatal dopamine release

1976 • 252 citations

Lack of effect of naloxone on pain perception in humans

1976 • 191 citations

On the role of endogenous opioid peptides: Failure of naloxone to influence shock escape threshold in the rat

1976 • 137 citations

Circadian Periodicity of Serum Prolactin Concentration in Man

1972 • 136 citations

Enkephalin: A potential modulator of noradrenaline release in rat brain

1976 • 135 citations

Effect of Stress on Circadian Periodicity in Serum LH and Prolactin Concentration

1972 • 112 citations

An inability to antagonize with naloxone the elevated nociceptive thresholds resulting from electrical stimulation of the mesencephalic central gray

1976 • 106 citations

Comparison between naloxone reversal of morphine and electrical stimulation induced analgesia in the rat mesencephalon

1976 • 105 citations

Daily Rhythm in the Noradrenaline Content of Rat Hypothalamus

1968 • 104 citations

A circadian rhythm of norepinephrine regionally in cat brain: its relationship to environmental lighting and to regional diurnal variations in brain serotonin.

1968 • 100 citations

Diurnal Variations in Plasma Corticosterone and Growth Hormone as Correlated with Regional Variations in Norepinephrine, Dopamine and Serotonin Content of Rat Brain

1975 • 92 citations

Circadian rhythm in cerebrospinal fluid noradrenaline of man and monkey

1976 • 86 citations

THE EFFECTS OF MORPHINE ON THE RELEASE OF NORADRENALINE FROM THE MOUSE VAS DEFERENS

1976 • 72 citations

Daily Susceptibility Rhythm to Morphine Analgesia

1969 • 36 citations

Effect of constant lighting on the morphine susceptibility rhythm

1972 • 17 citations

The 24-h pattern of human prolactin in serum.

1976 • 12 citations

Daily susceptibility variations to the morphine-induced hyperactivity of rats

1974 • 7 citations