Molecular Cloning of the Rhesus Glycoprotein Hormone α-Subunit Gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

Molecular Biology of the Pituitary Gonadotropins

1990 • 699 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.

1990 • 636 citations

Activators and targets

1990 • 582 citations

Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor

1988 • 525 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

Human Chorionic Gonadotropin Secreted by Preimplantation Embryos Cultured in Vitro

1984 • 223 citations

Cyclic AMP responsiveness of human gonadotropin-alpha gene transcription is directed by a repeated 18-base pair enhancer. Alpha-promoter receptivity to the enhancer confers cell-preferential expression.

1987 • 216 citations

The glycoprotein hormones: recent studies of structure‐function relationships

1988 • 214 citations

A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines.

1981 • 204 citations

Structure, Expression, and Evolution of the Genes for the Human Glycoprotein Hormones

1984 • 201 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Cytological localization of chorionic gonadotropin alpha and placental lactogen mRNAs during development of the human placenta.

1982 • 164 citations

Chorionic gonadotrophin-β mRNA, a trophoblast marker, is expressed in human 8-cell embryos derived from tripronucleate zygotes

1988 • 162 citations

Modulation of Gonadotropin Secretion by Corticosterone: Interaction with Gonadal Steroids and Mechanism of Action*

1987 • 158 citations

Distinct Adenosine 3′,5′-Monophosphate and Phorbol Ester-Responsive Signal Transduction Pathways Converge at the Level of Transcriptional Activation by the Interactions of DNA-Binding Proteins

1989 • 151 citations

Molecular Biology of Thyrotropin

1989 • 147 citations

THE ORIGIN AND FUNCTION OF HUMAN SYNCYTIOTROPHOBLASTIC GIANT CELLS.

1963 • 141 citations

The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription.

1988 • 127 citations

Effects of Glucocorticoids on Secretion of Luteinizing Hormone and Follicle-Stimulating Hormone by Female Rat Pituitary Cells in Vitro*

1985 • 113 citations

Expression of alpha subunit and luteinizing hormone beta genes in the ovine anterior pituitary. Estradiol suppresses accumulation of mRNAS for both alpha subunit and luteinizing hormone beta.

1983 • 100 citations

Thyroid Hormone Regulation of the Rat Glycoprotein Hormone α-Subunit Gene Promoter Activity

1989 • 99 citations

17β-Estradiol and Progesterone Inhibit Transcription of the Genes Encoding the Subunits of Ovine Follicle-Stimulating Hormone

1988 • 86 citations

Characterization and nucleotide sequence of the gene for the common α subunit of the bovine pituitary glycoprotein hormones

1983 • 82 citations

Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression.

1989 • 82 citations

Enhancer and Promoter Element Interactions Dictate Cyclic Adenosine Monophosphate Mediated and Cell-Specific Expression of the Glycoprotein Hormone α-Gene

1989 • 80 citations

CHORIONIC GONADOTROPIN SECRETION BY HUMAN EMBRYOS IN VITRO

1988 • 80 citations

Evidence for Only Oneβ-Luteinizing Hormone and Noβ-Chorionic Gonadotropin Gene in the Rat*

1984 • 80 citations

Regulation of ovine follicle-stimulating hormone beta-chain mRNA by 17 beta-estradiol in vivo and in vitro.

1982 • 73 citations

The human alpha subunit glycoprotein hormone gene utilizes a unique CCAAT binding factor.

1990 • 64 citations

Binding of Thyroid Hormone Receptors to the Rat Thyrotropin-β Gene

1989 • 63 citations

Effects of Glucocorticoids on Responsiveness of Luteinizing Hormone and Follicle-Stimulating Hormone to Gonadotropin-Releasing Hormone by Male Rat Pituitary Cells in Vitro*

1985 • 56 citations

Isolation and characterization of the human chorionic gonadotropin beta subunit (CG beta) gene cluster: regulation of transcriptionally active CG beta gene by cyclic AMP.

1988 • 54 citations

Cyclic AMP and phorbol esters interact synergistically to regulate expression of the chorionic gonadotropin genes.

1988 • 52 citations

Organization and Nucleotide Sequence of the Mouse α-Subunit Gene of the Pituitary Glycoprotein Hormones

1988 • 51 citations

Different Combinations of Regulatory Elements May Account For Expression of the Glycoprotein Hormone α-Subunit Gene in Primate and Horse Placenta

1990 • 50 citations

Absence of Detectable Chorionic Gonadotropin Subunit Messenger Ribonucleic Acids in the Rat Placenta throughout Gestation*

1985 • 49 citations

Distinct Adjacent Protein-binding Domains in the Glycoprotein Hormone α Gene Interact Independently with a cAMP-responsive Enhancer

1989 • 48 citations

Early secretion of chorionic gonadotrophin by marmoset embryos in vivo and in vitro

1988 • 48 citations

Regulation of Transfected Glycoprotein Hormone α-Gene Expression in Primary Pituitary Cell Cultures

1989 • 43 citations

Isolation and characterization of the gene encoding the a-subunit of the rat pituitary glycoprotein hormones

1988 • 42 citations

Expression and regulation of the pituitary- and placenta-specific human glycoprotein hormone alpha-subunit gene is restricted to the pituitary in transgenic mice.

1988 • 42 citations

Nucleotide (cDNA) sequence encoding the horse gonadotrophin α-subunit

1987 • 40 citations

Amplification of the Transcriptional Signal Mediated by the Tandem cAMP Response Elements of the Glycoprotein Hormone α-Subunit Gene Occurs through Several Distinct Mechanisms

1990 • 38 citations

The Luteotropic Activity of Rat Placenta Is Not Due to a Chorionic Gonadotropin^*

1983 • 35 citations

The Transcriptional Response of the Human Chorionic Gonadotropin β-Subunit Gene to cAMP is Cycloheximide Sensitive and is Mediated bycis-Acting Sequences Different from that Found in the α-Subunit Gene

1989 • 29 citations

OVERVIEW: Modulation by Sex Steroids and [<scp>d</scp>-TRP⁶, Des-Gly-NH₂¹⁰]Luteinizing Hormone (LH)-Releasing Hormone Ethylamide of α-Subunit and LHβ Messenger Ribonucleic Acid Levels in the Rat Anterior Pituitary Gland

1988 • 27 citations

Identification ofCis-Acting Promoter Elements Important for Expression of the Mouse Glycoprotein Hormone α-Subunit Gene in Thyrotropes

1990 • 26 citations

Progesterone Inhibits Basal Production of Follicle-Stimulating Hormone in Ovine Pituitary Cell Culture*

1985 • 25 citations

Identification of Thyrotroph-Specific Factors andCis-Acting Sequences of the Murine Thyrotropinβ Subunit Gene

1989 • 21 citations

LEVELS OF IMMUNOGLOBULINS IN THE SERUM AND UTERINE FLUID OF WOMEN USING AN INTRAUTERINE CONTRACEPTIVE DEVICE

1974 • 15 citations