Tissue specific metabolism of 1α,25‐dihydroxy‐20‐epi‐vitamin D3 into new metabolites with significant biological activity: Studies in rat osteosarcoma cells (UMR 106 and ROS 17/2.8)

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

20-EPI-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responses

1991 • 320 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

Structure-function relationships in the vitamin D endocrine system

1995 • 268 citations

Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation

1989 • 246 citations

Calcitroic acid, end product of renal metabolism of 1,25-dihydroxyvitamin D3 through the C-24 oxidation pathway

1989 • 245 citations

Vitamin D, a pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications

1994 • 176 citations

Biological Esterification of Steroids*

1998 • 124 citations

1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion.

1999 • 103 citations

1?,25-Dihydroxy-3-Epi-vitamin D3, a natural metabolite of 1?,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion

1999 • 93 citations

Differentiation-Related Pathways of 1α,25-Dihydroxycholecalciferol Metabolism in Human Colon Adenocarcinoma-Derived Caco-2 Cells: Production of 1α,25-Dihydroxy-3epi-cholecalciferol

1998 • 78 citations

Increased biological activity of 20-EPI-1,25-dihydroxyvitamin D3 is due to reduced catabolism and altered protein binding

1994 • 74 citations

Isolation and identification 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3, a new metabolite of 1,25-dihydroxyvitamin D3 produced in rat kidney

1987 • 68 citations

Metabolism of 1α,25-dihydroxyvitamin D3 and its C-3 epimer 1α,25-dihydroxy-3-epi-vitamin D3 in neonatal human keratinocytes

2001 • 60 citations

Metabolic pathways from 1 alpha,25-dihydroxyvitamin D3 to 1 alpha,25-dihydroxyvitamin D3-26,23-lactone. Stereo-retained and stereo-selective lactonization.

1987 • 60 citations

1 alpha,25-Dihydroxy-20-epi-vitamin D3: an extraordinarily potent inhibitor of leukemic cell growth in vitro

1994 • 60 citations

Biological Esterification of Steroids

1998 • 56 citations

Production of 1α,25-Dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed

1999 • 53 citations

Inhibition of 25-hydroxyvitamin D3-1-hydroxylase by chronic metabolic acidosis

1982 • 38 citations

Enhanced biological activity of 1α,25-dihydroxy-20-epi-vitamin D3, the C-20 epimer of 1α,25-dihydroxyvitamin D3, is in part due to its metabolism into stable intermediary metabolites with significant biological activity

1999 • 27 citations

Effects of 1,25‐dihydroxyvitamin D₃ and its 20‐epi analogues (MC 1288, MC 1301, KH 1060), on clonal keratinocyte growth: evidence for differentiation of keratinocyte stem cells and analysis of the modulatory effects of cytokines

1997 • 26 citations

Metabolism of 1α,25-dihydroxyvitamin D3 in human promyelocytic leukemia (HL-60) cells: In vitro biological activities of the natural metabolites of 1α,25-dihydroxyvitamin D3 produced in HL-60 cells

2001 • 20 citations

20-EPI-Vitamin D3 Analogs

1996 • 15 citations

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