Biological Esterification of Steroids*

ESTERASES IN HUMAN LEUKOCYTES

1973 • 905 citations

Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism

1991 • 641 citations

Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases.

1990 • 491 citations

Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men.

1994 • 387 citations

Cholesterol Ester Metabolism

1965 • 333 citations

A Simple and Sensitive Microtiter Plate Estrogen Bioassay Based on Stimulation of Alkaline Phosphatase in Ishikawa Cells: Estrogenic Action of Δ⁵Adrenal Steroids*

1990 • 180 citations

Antioxidant Protection of LDL by Physiological Concentrations of 17β-Estradiol

1997 • 164 citations

Cholesterol Esterase Stimulation by Luteinizing Hormone in Luteinized Rat Ovaries

1969 • 144 citations

Monoclonal antibodies to the Mr 74,000 cholesteryl ester transfer protein neutralize all of the cholesteryl ester and triglyceride transfer activities in human plasma.

1988 • 131 citations

Interaction of Δ⁵-Androstene-3β,17β-diol with Estradiol and Dihydrotestosterone Receptors in Human Myometrial and Mammary Cancer Tissue1

1975 • 123 citations

Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain

1989 • 120 citations

Evidence that Steroid Sulfates Serve as Biosynthetic Intermediates.^* IV. Conversion of Cholesterol Sulfate in vivo to Urinary C₁₉ and C₂₁ Steroidal Sulfates^†

1964 • 114 citations

Estradiol fatty acid esters. The isolation and identification of the lipoidal derivative of estradiol synthesized in the bovine uterus.

1982 • 113 citations

The Intrarenal Localization of Mineralocorticoid Receptors and 11β-Dehydrogenase: Immunocytochemical Studies

1989 • 105 citations

Evidence that Steroid Sulfates Serve as Biosynthetic Intermediates: In vivo Conversion of Pregnenolone-Sulfate-S³⁵ to Dehydroisoandrosterone Sulfate-S^35*

1963 • 95 citations

Lipoidal Derivative of Estradiol: The Biosynthesis of a Nonpolar Estrogen Metabolite*

1981 • 84 citations

The naturally occurring C-17 fatty acid esters of estradiol are long-acting estrogens

1985 • 79 citations

A new class of apolar ecdysteroid conjugates: esters of 20-hydroxy-ecdysone with long-chain fatty acids in ticks

1985 • 74 citations

The Interaction of C-17 Esters of Estradiol with the Estrogen Receptor*

1984 • 74 citations

Estradiol Fatty Acid Esters Occur Naturally in Human Blood

1983 • 72 citations

Evidence that Steroid Sulfates Serve as Biosynthetic Intermediates. II. In Vitro Conversion of Pregnenolone-³H Sulfate-³⁵S to 17α-Hydroxypregnenolone-³H Sulfate-³⁵S^*

1964 • 71 citations

Detection in bovine adrenal cortex of a lipoidal substance that yields pregnenolone upon treatment with alkali.

1977 • 71 citations

Estrogenic Effects of 5-Androstene-3β,17β-Diol at Physiological Concentrations and Its Possible Implication in the Etiology of Breast Cancer*

1983 • 69 citations

The Clearance and Metabolism of Estradiol and Estradiol-17-Esters in the Rat*

1985 • 66 citations

THE TESTICULAR HORMONE

1929 • 64 citations

Metabolism of ecdysteroids during the vitellogenesis of the tick Ornithodoros moubata (Ixodoidea, Argasidae): Accumulation of apolar metabolites in the eggs

1984 • 61 citations

PHYSIOLOGY OF THE CORPUS LUTEUM

1930 • 60 citations

Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones

1988 • 60 citations

Substrate and inhibitor specificity of the cholesterol oxidase in bovine adrenal cortex

1966 • 59 citations

Long-lived testosterone esters in the rat.

1995 • 58 citations

The metabolism of ingested and injected [³H]ecdysone by final instar larvae of Heliothis armigera

1987 • 58 citations

Isolation and identification of apolar metabolites of ingested 20-hydroxyecdysone in frass ofHeliothis virescens larvae

1987 • 55 citations

The Isolation of Cholesterol Sulfate from Bovine Adrenals

1964 • 55 citations

Measurement of estradiol-17-fatty acid esters in human tissues.

1992 • 54 citations

The isolation and characterization of estradiol-fatty acid esters in human ovarian follicular fluid. Identification of an endogenous long-lived and potent family of estrogens

1993 • 49 citations

Cholesterol and cholesterol sulfate as substrates for the adrenal side-chain cleavage enzyme

1974 • 48 citations

The conversion of cholesterol-3H-sulfate-35S into pregnenolone-3H-sulfate-35S by sonicated bovine adrenal mitochondria

1967 • 43 citations

Esterification-deesterification of estradiol by human mammary cancer cells in culture

1986 • 43 citations

The agonistic and antagonistic actions of estriol

1984 • 43 citations

Utilization of various sterols by lecithin‐cholesterol acyltransferase as acyl acceptors

1979 • 43 citations

The identification, quantification and possible origin of non-polar conjugates in human plasma

1985 • 42 citations

Formation of estradiol-17β fatty acyl 17-esters in mammary tumors

1982 • 42 citations

Characterization of the lipoidal derivatives of pregnenolone prepared by incubation of the steroid with adrenal mitochondria.

1979 • 41 citations

Naturally occurring lipoidal derivatives of 3β-hydroxy-5-pregnen-20-one; 3β, 17α-dihydroxy-5-pregnen-20-one and 3β-hydroxy-5-androsten-17-one

1979 • 39 citations

Biosynthesis of lipoidal derivatives of pregnenolone and dehydroisoandrosterone by the adrenal.

1980 • 38 citations

Acetylation and hydroxylation of 5α-androstane-3β,17β-diol by prostate and epididymis

1974 • 37 citations

Synthesis of estradiol fatty acid esters by human breast tumors: Fatty acid composition and comparison to estrogen and progesterone receptor content

1985 • 37 citations

Über isomere Follikelhormone. Untersuchungen über das weibliche Sexualhormon, 7. Mitteilung.

1932 • 37 citations

The activation of the male sex hormones. I

1936 • 36 citations

Identification of fatty acid esters of pregnenolone and allopregnanolone from bovine corpora lutea.

1980 • 36 citations

Characterization of steroid hormone ester hydrolyzing enzymes in liver microsomes

1981 • 35 citations

Isolation of apolar ecdysteroid conjugates from newly-laid oothecae of Periplaneta americana

1986 • 35 citations

Selective turnover of the essential fatty acid ester components of estradiol-17β lipoidal derivatives formed by human mammary cancer cells in culture

1987 • 34 citations

Long-acting estrogenic responses of estradiol fatty acid esters

1989 • 34 citations

Fatty acid esters of testosterone in rat brain: Identification, distribution, and some properties of enzymes which synthesize and hydrolyze the esters

1973 • 32 citations

Nonspecific and metabolic interactions between steroid hormones and human plasma lipoproteins

1990 • 32 citations

Identification of the endogenous apolar ecdysteroid conjugates present in newly-laid eggs of the house cricket (Acheta domesticus) as 22-long-chain fatty acyl esters of ecdysone

1989 • 32 citations

A Comparison of the Fatty Acid Esters of Estradiol and Corticosterone Synthesized by tIssues of the Rat

1989 • 32 citations

Actions of an Estradiol-17-Fatty Acid Ester in Estrogen Target Tissues of the Rat: Comparison with Other C-17 Metabolites and a Pharmacological C-17 Ester*

1989 • 32 citations

Metabolic conversion of six steroid hormones by human plasma high-density lipoprotein

1991 • 32 citations

Metabolism of Estradiol Fatty Acid Esters in Man*

1985 • 32 citations

The activation of the male sex hormones. II

1936 • 32 citations

A comparison of the esterification of steroids by rat lecithin:cholesterol acyltransferase and acyl coenzyme A:cholesterol acyltransferase.

1995 • 31 citations

Extensive Esterification of Adrenal C19-Δ5-Sex Steroids to Long-Chain Fatty Acids in the ZR-75-1 Human Breast Cancer Cell Line

1989 • 30 citations

Properties of fatty acyl-coenzyme A: estradiol-17β acyltransferase in bovine placenta microsomes

1988 • 29 citations

Binding of Estradiol-17-Fatty Acid Esters to Plasma Proteins*

1987 • 29 citations

Purification of guanylate cyclase from rat liver supernatant.

1978 • 29 citations

Cholesterol Sulfate: Some Aspects of Its Biosynthesis and Uptake by Tissues from Blood

1974 • 28 citations

Esterification of dehydroepiandrosterone by human plasma HDL3

1989 • 28 citations

Acetylation of cortisol by neonatal rat brain in vitro

1967 • 27 citations

Estradiol esters can replace 17β-estradiol in the stimulation of DNA and esterase synthesis by MCF-7 cells: A possible role for the estrogen-sensitive MCF-7 cell esterase

1991 • 26 citations

Biosynthesis of estradiol-17β fatty acyl esters by microsomes derived from bovine liver and adrenals

1989 • 26 citations

Steroid fatty acid esters in adrenals and plasma: effects of ACTH

1990 • 25 citations

Δ5-3β-Hydroxysteroid acyl transferase activity in the rat brain

1992 • 25 citations

Elevated levels of endogenous pregnenolone fatty acid esters in follicular fluid high density lipoproteins support progesterone synthesis in porcine granulosa cells.

1992 • 25 citations

Formation of pregnenolone- and dehydroepiandrosterone-fatty acid esters by lecithin-cholesterol acyltransferase in human plasma high density lipoproteins

1996 • 24 citations

Side chain cleavage of some cholesterol esters.

1979 • 24 citations

Androsterone Long Chain Fatty Acid Esters in Human Breast Cyst Fluid*

1985 • 24 citations

Formation of lipoidal steroids in follicular fluid

1989 • 24 citations

ZR-75-1 breast cancer cells generate nonconjugated steroids from low density lipoprotein-incorporated lipoidal dehydroepiandrosterone.

1993 • 23 citations

Solubilisation and reconstitution of acylcoenzyme A:estradiol-17β acyltransferase

1987 • 22 citations

Lipoproteins: Carriers of dehydroepiandrosterone fatty acid esters in human serum

1989 • 21 citations

Characterization of steroid hormone association with human plasma lipoproteins

1989 • 21 citations

Origin of Estradiol Fatty Acid Esters in Human Ovarian Follicular Fluid1

1995 • 20 citations

Estrogenic action of estriol fatty acid esters

1991 • 20 citations

Analysis of [3H]estradiol-17beta metabolites in calf perirenal fat

1994 • 19 citations

Transfer of Dehydroepiandrosterone- and Pregnenolone-Fatty Acid Esters between Human Lipoproteins¹

1997 • 19 citations

ISOLATION AND IDENTIFICATION OF ADRENOCORTICAL STEROIDS IN HUMAN PERIPHERAL PLASMA. I. A NATURALLY OCCURRING C₂₁STEROID ACETATE (11-DEHYDROCORTICOSTERONE ACETATE) AND “FREE” TETRAHYDROCORTISONE IN NORMAL PLASMA*

1960 • 19 citations

Isolation and identification of adrenocortical steroids in human peripheral blood

1963 • 19 citations

Purification and properties of an esterase from human breast cyst fluid.

1991 • 19 citations

Glucosiduronidation and esterification of androsterone by human breast tumors invitro

1981 • 19 citations

11β-Hydroxysteroid dehydrogenase in renal collecting duct cells

1994 • 18 citations

Synthesis and biological assessment of long-acting estradiol fatty acid esters in ovariectomized rats

1985 • 17 citations

Wide spectrum of steroids serving as substrates for the formation of lipoidal derivatives in ZR-75-1 human breast cancer cells

1990 • 16 citations

Formation and turnover of long-chain fatty acid esters of 5-androstene-3β,17β -diol in estrogen receptor positive and negative human mammary cancer cell lines in culture

1988 • 16 citations

Administration of pregnenolone and dehydroepiandrosterone to guinea pigs and rats causes the accumulation of fatty acid esters of pregnenolone and dehydroepiandrosterone in plasma lipoproteins

1992 • 16 citations

Inhibition by Cholesterol Analogues of the Side-chain Cleavage of Cholesterol and 20α-Hydroxycholesterol in a Preparation of Hog Adrenocortical Mitochondria

1969 • 16 citations

Acyl-CoA: Ecdysone acyltransferase activity from the ovary of P. americana

1988 • 15 citations

Non-polar extracts of serum from males contain covert radioimmunoassayable testosterone

1989 • 15 citations

The lipoidal derivatives of steroids as biosynthetic intermediates.

1980 • 15 citations

Properties of corticosteroid-21-O-acetyltransferase from the baboon brain

1968 • 14 citations

STUDIES ON THE ADRENAL CORTEX

1931 • 14 citations

Relative duration of action of various esters of oestrone, oestradiol and oestriol

1937 • 13 citations

In vitro metabolism of [3H] corticosterone by mammary glands from lactating rats. Isolation and identification of 21-acyl[3H]corticosterone.

1985 • 13 citations

Characterization of ecdysteroid-22-O-acyltransferase from tobacco budworm, Heliothis virescens

1992 • 13 citations

The Conversion of Progesterone into 5α-Pregnane-3,20-dione, 3β-Hydroxy-5α-pregnan-20-one, and Its Fatty Acid Esters by Preparations of Bovine Corpora Lutea*

1982 • 12 citations

Biological Activity of the Fatty Acid Ester Metabolites of Corticoids*

1990 • 12 citations

Transfer of Dehydroepiandrosterone- and Pregnenolone-Fatty Acid Esters between Human Lipoproteins

1997 • 11 citations

Side-chain cleavage of cholesterol esters by human cytochrome P-450scc

1996 • 11 citations

THE ACETYLATION OF TESTOSTERONE BY RAT AND MOUSE MAMMARY TISSUE

1964 • 11 citations

The biosynthesis of D-ring fatty acid esters of estriol.

1991 • 11 citations

Changes in the metabolic pattern of estrogens as a function of age in cultured myometrial cells: Synthesis of a lipoidal derivative of estradiol

1986 • 10 citations

Aromatase and testosterone fatty acid esters: the search for a cryptic biosynthetic pathway to estradiol esters

1992 • 9 citations

The influence of 21-acylation of corticosterone on its binding affinity for corticosteroid-binding globulin

1981 • 8 citations

The Δ5-3β-hydroxy steroid acyl transferase activities in tissues of the male rat and sheep

1997 • 8 citations

Presence of fatty acid esters of pregnenolone in follicular fluid from women undergoing follicle stimulation

1989 • 8 citations

A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer

1985 • 8 citations

Esterase activity in human breast cyst fluid: associations with steroid sulfates and cations

1992 • 7 citations

The nonspecific esterases of human mononuclear leukocytes metabolize arylamine carcinogens and steroids esters

1989 • 6 citations

Dehydroepiandrosterone therapeutics: Acetylation of DHA in mouse liver

1988 • 6 citations

Separation of C-17 fatty acid esters of 17β-estradiol by reversed-phase high-performance liquid chromatography

1989 • 6 citations

Long-chain fatty acid esters of 5-androstene-3β,17β-diol: Composition and turnover in human mammary cancer cells in culture

1989 • 6 citations

IN-VITRO UPTAKE AND METABOLISM OF [3H]CORTICOSTERONE BY MAMMARY GLANDS FROM PREGNANT, LACTATING AND POST-LACTATIONAL RATS AND BY PARAMETRIAL ADIPOSE TISSUE FROM LACTATING RATS

1981 • 6 citations

THE INFLUENCE OF ESTERIFICATION UPON THE BIOLOGICAL ACTIVITY OF OESTRADIOL IN RATS AND MICE

1948 • 5 citations

In vitro metabolism of adrenocortical hormones by mammary glands of lactating rats. A comparative study

1986 • 5 citations

Serum of patients with prostatic cancer or benign prostatic hypertrophy contains nonpolar testosterone

1990 • 5 citations

Adrenocortical hormones and lactation: metabolism of 3H-corticosterone and 3H-aldosterone by rat mammary gland minces and by the nuclear fraction of the homogenates.

1986 • 3 citations