Recombinant factor VIIa improves clot formation but not fibrolytic potential in patients with cirrhosis and during liver transplantation

Transection of the oesophagus for bleeding oesophageal varices

1973 • 7,698 citations

Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots

1970 • 3,260 citations

Purification and Characterization of TAFI, a Thrombin-activable Fibrinolysis Inhibitor

1995 • 684 citations

TAFI, or Plasma Procarboxypeptidase B, Couples the Coagulation and Fibrinolytic Cascades through the Thrombin-Thrombomodulin Complex

1996 • 641 citations

Platelet activity of high‐dose factor VIIa is independent of tissue factor

1997 • 544 citations

A Study of the Mechanism of Inhibition of Fibrinolysis by Activated Thrombin-activable Fibrinolysis Inhibitor

1998 • 391 citations

Single bilayer vesicles prepared without sonication physico-chemical properties

1976 • 381 citations

Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors

1998 • 362 citations

Aprotinin and transfusion requirements in orthotopic liver transplantation: a multicentre randomised double-blind study

2000 • 309 citations

Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis

1995 • 295 citations

Thrombin-Activatable Fibrinolysis Inhibitor Deficiency in Cirrhosis Is Not Associated With Increased Plasma Fibrinolysis

2001 • 276 citations

Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: A preliminary study

1997 • 263 citations

Plasma carboxypeptidases as regulators of the plasminogen system.

1995 • 258 citations

REDUCED TRANSFUSION REQUIREMENTS BY RECOMBINANT FACTOR VIIa IN ORTHOTOPIC LIVER TRANSPLANTATION

2001 • 250 citations

Tranexamic Acid Reduces Blood Loss, Transfusion Requirements, and Coagulation Factor Use in Primary Orthotopic Liver Transplantation

1996 • 250 citations

Thrombin-mediated activation of factor XI results in a thrombin-activatable fibrinolysis inhibitor-dependent inhibition of fibrinolysis.

1997 • 234 citations

Plasma TAFI Levels Influence the Clot Lysis Time in Healthy Individuals in the Presence of an Intact Intrinsic Pathway of Coagulation

1998 • 223 citations

The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor.

1993 • 202 citations

Hageman factor fragment inhibitor in corn seeds: Purification and characterization

1980 • 168 citations

Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A

2002 • 155 citations

Fibrinolysis during liver transplantation in humans: role of tissue- type plasminogen activator

1988 • 142 citations

Recombinant Activated Factor VII (rFVIIa) Acutely Normalizes Prothrombin Time in Patients with Cirrhosis During Bleeding from Oesophageal Varices

2001 • 136 citations

Coagulation defects in liver disease

1994 • 132 citations

Inhibition of thrombin generation by the zymogen factor VII: implications for the treatment of hemophilia A by factor VIIa

2000 • 131 citations

A shift in balance between profibrinolytic and antifibrinolytic factors causes enhanced fibrinolysis in cirrhosis

1991 • 119 citations

Coagulation and Fibrinolysis in Orthotopic Liver Transplantation: Current Views and Insights

1993 • 110 citations

Hemostasis in liver transplantation

1989 • 104 citations

Treatment of Patients with Factor VIII and Factor IX Inhibitors with Special Focus on the Use of Recombinant Factor VIIa

1999 • 92 citations

Haemostatic problems in liver disease.

1986 • 85 citations

Human monocytes support factor X activation by factor VIIa, independent of tissue factor: implications for the therapeutic mechanism of high- dose factor VIIa in hemophilia [see comments]

1994 • 72 citations

Coagulation problems in liver disease

2000 • 61 citations

Fibrinogen blocks the autoactivation and thrombin-mediated activation of factor XI on dextran sulfate.

1992 • 57 citations

Characterization of mini-protein S, a recombinant variant of protein S that lacks the sex hormone binding globulin-like domain

1998 • 49 citations

Pathophysiology and Treatment of Variceal Hemorrhage

1996 • 46 citations

Effectiveness of the Recombinant Factor VIIa in Patients with the Coagulopathy of Advanced Child's B and C Cirrhosis

2000 • 45 citations