Pathophysiology and Treatment of Variceal Hemorrhage

Prediction of the First Variceal Hemorrhage in Patients with Cirrhosis of the Liver and Esophageal Varices

1988 • 1,117 citations

Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage

1990 • 731 citations

The Transjugular Intrahepatic Portosystemic Stent-Shunt Procedure for Variceal Bleeding

1994 • 718 citations

Endoscopic Sclerotherapy as Compared with Endoscopic Ligation for Bleeding Esophageal Varices

1992 • 693 citations

Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators

1985 • 367 citations

Endoscopic Ligation Compared with Sclerotherapy for the Treatment of Bleeding Esophageal Varices

1993 • 346 citations

PATHOPHYSIOLOGY OF PORTAL HYPERTENSION

1992 • 309 citations

Complications of transjugular intrahepatic portosystemic shunt: a comprehensive review.

1993 • 307 citations

Controlled Trial of Propranolol for the Prevention of Recurrent Variceal Hemorrhage in Patients with Cirrhosis

1983 • 303 citations

[Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome].

1993 • 295 citations

Randomised trial of variceal banding ligation versus injection sclerotherapy for bleeding oesophageal varices

1993 • 289 citations

Sclerotherapy with or without Octreotide for Acute Variceal Bleeding

1995 • 275 citations

Endoscopic Sclerotherapy versus Port Acaval Shunt in Patients with Severe Cirrhosis and Acute Variceal Hemorrhage

1987 • 274 citations

Endoscopic Obliteration of Large Esophagogastric Varices with Bucrylate

1986 • 265 citations

Propranolol Compared with Propranolol plus Isosorbide-5-Mononitrate for Portal Hypertension in Cirrhosis

1991 • 254 citations

PROPHYLACTIC PORTACAVAL ANASTOMOSIS

1972 • 239 citations

A prospective, randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices.

1995 • 221 citations

Tumor necrosis factor α: A major contributor to the hyperdynamic circulation in prehepatic portal-hypertensive rats

1995 • 219 citations

Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats

1993 • 218 citations

Efficacy of balloon tamponade in treatment of bleeding gastric and esophageal varices

1988 • 213 citations

Measurement of Azygos Venous Blood Flow by a Continuous Thermal Dilution Technique: An Index of Blood Flow Through Gastroesophageal Collaterals in Cirrhosis†

1984 • 213 citations

Circulating levels of endothelin in cirrhosis

1993 • 202 citations

Octreotide infusion or emergency sclerotherapy for variceal haemorrhage

1993 • 201 citations

Prevalence of spontaneous hepatofugal portal flow in liver cirrhosis

1991 • 196 citations

Pathogenesis of arterial hypotension in cirrhotic rats with ascites: Role of endogenous nitric oxide

1992 • 190 citations

Acute Esophageal Variceal Sclerotherapy

1986 • 187 citations

A prospective, randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices

1995 • 180 citations

A Comparison of Sclerotherapy with Staple Transection of the Esophagus for the Emergency Control of Bleeding from Esophageal Varices

1989 • 164 citations

Percutaneous Transjugular Portosystemic Shunt

1991 • 158 citations

The Nitric Oxide hypothesis and the hyperdynamic circulation in cirrhosis

1994 • 152 citations

Incidence of shunt occlusion or stenosis following transjugular intrahepatic portosystemic shunt placement

1994 • 139 citations

Effects of prostaglandin inhibition on systemic and hepatic hemodynamics in patients with cirrhosis of the liver

1985 • 132 citations

Reduced vascular sensitivity to norepinephrine in portal-hypertensive rats

1985 • 123 citations

A prospective randomized trial comparing somatostatin and sclerotherapy in the treatment of acute variceal bleeding

1994 • 115 citations

Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo-controlled clinical trial

1989 • 112 citations

In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade

1992 • 110 citations

Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: A multicenter randomized trial

1993 • 99 citations

A meta-analysis of somatostatin versus vasopressin in the management of acute esophageal variceal hemorrhage

1995 • 98 citations

Comparison between ultrasonographic signs and the degree of portal hypertension in patients with cirrhosis

1990 • 93 citations

Vascular hyporesponsiveness to endothelin 1 in rats with cirrhosis

1994 • 84 citations

Reduction of variceal pressure by propranolol: Comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis

1993 • 84 citations

Circadian variations of portal pressure and variceal hemorrhage in patients with cirrhosis

1994 • 83 citations

Hemodynamic evaluation of octreotide in patients with hepatitis B-related cirrhosis

1992 • 80 citations

Propranolol in Prevention of Rebleeding from Oesophageal Varices during the Course of Endoscopic Sclerotherapy

1989 • 80 citations

Portal Hypertension

1989 • 79 citations

The endothelin-1 binding site in rat liver tissue: Light- and electron-microscopic autoradiographic studies

1993 • 78 citations

Effects of vasopressin on the intravariceal pressure in patients with cirrhosis: Comparison with the effects on portal pressure

1988 • 78 citations

Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double-blind randomized echo-doppler study

1995 • 69 citations

Natural history and prognosis of variceal bleeding

1992 • 63 citations

Manometry of esophageal varices: Comparison of an endoscopic balloon technique with needle puncture

1993 • 61 citations

WHICH PORTOSYSTEMIC SHUNT IS BEST?

1992 • 60 citations

Sclerotherapy for male alcoholic cirrhotic patients who have bled from esophageal varices: Results of a randomized, multicenter clinical trial

1994 • 59 citations

METHODS TO EVALUATE PORTAL HYPERTENSION

1992 • 53 citations

Narrow-diameter portacaval shunts for management of variceal bleeding

1994 • 48 citations

Reduction of variceal pressure by propranolol: Comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis,

1993 • 46 citations

Glucagon in portal hypertension

1994 • 39 citations

Hyperglucagonemia and hyperkinetic circulation after portocaval shunt in the rat

1987 • 36 citations

Systemic and portal haemodynamic changes following triglycyllysine vasopressin plus nitroglycerin administration in patients with hepatitis B-related cirrhosis

1990 • 32 citations

Reduction of transmural oesophageal variceal pressure by metoclopramide

1991 • 27 citations

Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: A multicenter randomized trial,

1993 • 16 citations

The management of active variceal bleeding

1993 • 9 citations

Ethanol consumption worsens hepatic hemodynamics in patients with alcoholic cirrhosis and portal hypertension

1993 • 4 citations

Increased intrahepatic resistance in portal hypertension is mediated by endothelin*1

1993 • 3 citations