Haemostatic problems in liver disease.

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1973 • 1,303 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

Human Plasma Protein C

1979 • 511 citations

Bleeding after liver biopsy does not correlate with indices of peripheral coagulation

1981 • 350 citations

Response of Factor VIII/von Willebrand Factor to DDAVP in Healthy Subjects and Patients with Haemophilia A and von Willebrand's Disease

1981 • 314 citations

Distribution of factor VIII mRNA and antigen in human liver and other tissues

1985 • 293 citations

Familial Thrombosis Due to Antithrombin III Deficiency

1974 • 290 citations

DEFICIENCIES OF PROTEIN C, AN INHIBITOR OF BLOOD COAGULATION

1982 • 224 citations

Acquired Vitamin K-Dependent Carboxylation Deficiency in Liver Disease

1981 • 224 citations

Transvenous Liver Biopsy

1982 • 208 citations

Vitamin K and the Biosynthesis of Prothrombin

1972 • 146 citations

Kinetic and functional studies of platelets, fibrinogen, and plasminogen in patients with hepatic cirrhosis.

1982 • 132 citations

Platelet lipid composition and platelet aggregation in human liver disease

1981 • 129 citations

Activation of Protein C In Vivo

1982 • 128 citations

Abnormal sialic acid content of the dysfibrinogenemia associated with liver disease.

1978 • 122 citations

MAGNESIUM DEFICIENCY

1976 • 117 citations

The Risk of Bleeding after Percutaneous Liver Biopsy

1982 • 96 citations

Significance of intravascular coagulation and fibrinolysis in acute hepatic failure

1974 • 93 citations

The role of sialic acid in the dysfibrinogenemia associated with liver disease: distribution of sialic acid on the constituent chains

1983 • 92 citations

Thromboembolic Complications

1975 • 91 citations

The Defibrination Syndrome

1966 • 91 citations

A functional assay for protein C in human plasma

1983 • 90 citations

Acquired dysfibrinogenaemia in liver disease.

1982 • 89 citations

Liver biopsy today

1985 • 84 citations

Abnormal Fibrin Polymerization in Liver Disease

1976 • 80 citations

Disseminated Intravascular Coagulation with the Peritoneovenous Shunt

1979 • 76 citations

Coagulation Studies as a Prognostic Index in Acute Liver Failure

1975 • 73 citations

Behaviour of antithrombin 3 in liver disease.

1973 • 68 citations

Platelet function in chronic liver disease

1979 • 67 citations

Antithrombin III transfusion in patients with hepatic cirrhosis

1982 • 63 citations

Prothrombin synthesis in the dog

1964 • 59 citations

Elevated antihemophilic factor (AHF, factor VIII) procoagulant activity and AHF-like antigen in alcoholic cirrhosis of the liver.

1974 • 56 citations

Quantitative Estimation of Coagulation Factors in Liver Disease. The Diagnostic and Prognostic Value of Factor XIII, Factor V and Plasminogen

1978 • 55 citations

Localization of factor VIIIC: antigen in guinea‐pig tissues and isolated liver cell fractions

1984 • 55 citations

TREATMENT OF ASCITES BY CONTINUOUS ULTRAFILTRATION AND REINFUSION OF PROTEIN CONCENTRATE

1974 • 52 citations

Blood Coagulation Changes in Liver Diseases

1965 • 51 citations

A controlled trial of heparin therapy in the coagulation defect of paracetamol-induced hepatic necrosis

1974 • 51 citations

Disseminated intravascular coagulation in hepatic failure treated with antithrombin III

1981 • 44 citations

Factor VII as a marker of hepatocellular synthetic function in liver disease.

1976 • 43 citations

Synthesis and secretion of plasma proteins by embryonic chick hepatocytes: changing patterns during the first three days of culture.

1978 • 41 citations

Platelet‐Associated IgG in Acute and Chronic Hepatic Diseases

1981 • 41 citations

PLATELET ASSOCIATED IMMUNOGLOBULINS IN CHRONIC LIVER DISEASE

1981 • 37 citations

Bleeding in Cirrhotic Patients: A Precipitating Factor due to Intravascular Coagulation or to Hepatic Failure?

1983 • 37 citations

Coagulation factor concentrate in the treatment of the haemorrhagic diathesis of fulminant hepatic failure

1974 • 37 citations

Elevation of Factor VIII in Acute Fatal Liver Necrosis

1970 • 33 citations

Factor IX Complex

1980 • 32 citations

The Cellular Localization of Fibrinogen as Revealed by the Fluorescent Antibody Technique¹

1963 • 31 citations

Antithrombin III Infusion in Patients Undergoing Peritoneovenous Shunt Operation: Failure in the Prevention of Disseminated Intravascular Coagulation

1983 • 29 citations

Turnover of radiolabelled plasminogen and prothrombin in cirrhosis of the liver

1978 • 27 citations

Fate of the activated gamma-carbon-hydrogen bond in the uncoupled vitamin K-dependent gamma-glutamyl carboxylation reaction.

1983 • 25 citations

Improvement of Some Blood Coagulation Factors in Cirrhotic Patients Treated with Low Doses of Heparin

1982 • 25 citations

Study of acquired dysfibrinogenaemia in liver disease

1980 • 24 citations

The effect of liver disease on factors V, VIII and protein C

1985 • 23 citations

Studies on Proconvertin (Factor VII) V. Biosynthesis in Suspension Cultures of Rat Liver Cells

1964 • 22 citations

Prothrombin Antigen and Coagulant Activity in Patients With Liver Disease

1982 • 22 citations

Platelet dynamics in chronic liver disease using the 111Indium oxine label.

1983 • 21 citations

Coagulation Activities in Perfused Organs: Regulation by Addition of Animal Plasmas

1974 • 19 citations

Megathrombocytes, Platelet Regeneration Time and Platelet-Associated IgG in Idiopathic Thrombocytopenic Purpura and in Thrombocytopenia Associated with Chronic Liver Disease

1981 • 13 citations

Multivariate analysis of clinical and biological data in cirrhotic patients: application to prognosis

1981 • 11 citations

Plasma factor Xa-inhibitory activity in alcoholic liver disease and the effect of heparin

1974 • 11 citations

Antithrombin III Infusion During Fulminant Hepatic Failure

1981 • 10 citations

Hypercoagulability in acute esophageal variceal bleeding

1981 • 8 citations

Antithrombin III Substitution In Acute Hepatic Failure Due To CCl4 Intoxication

1981 • 7 citations

Synthesis of coagulation factors by a clonal strain of rat hepatoma cells

1972 • 7 citations

Thrombo-embolic Complications

1979 • 7 citations

Experimental dmna induced hepatic necrosis: Early course of haemostatic disorders in the rat

1985 • 5 citations