Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB

SCOP: A structural classification of proteins database for the investigation of sequences and structures

1995 • 6,372 citations

Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)=O Complex

2003 • 875 citations

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

2002 • 723 citations

Alkylation damage in DNA and RNA—repair mechanisms and medical significance

2004 • 613 citations

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

2003 • 611 citations

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

2002 • 590 citations

Reversal of DNA alkylation damage by two human dioxygenases

2002 • 392 citations

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

1999 • 382 citations

Repairing DNA-methylation damage

2004 • 359 citations

Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis thaliana

2002 • 335 citations

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli

2004 • 234 citations

X-ray Crystal Structure of Escherichia coli Taurine/α-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates^,

2002 • 216 citations

AlkB Restores the Biological Function of mRNA and tRNA Inactivated by Chemical Methylation

2004 • 194 citations

AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo

2005 • 189 citations

Kinetic Dissection of the Catalytic Mechanism of Taurine:α-Ketoglutarate Dioxygenase (TauD) from Escherichia coli

2005 • 186 citations

A new gene (alkB) of Escherichia coli that controls sensitivity to methyl methane sulfonate

1983 • 175 citations

Crystal structure of a clavaminate synthase–Fe(II)–2‐oxoglutarate–substrate–NO complex: evidence for metal centred rearrangements

2002 • 152 citations

Rapid Freeze-Quench ⁵⁷Fe Mössbauer Spectroscopy: Monitoring Changes of an Iron-Containing Active Site during a Biochemical Reaction

2005 • 122 citations

Substrate specificities of bacterial and human AlkB proteins

2004 • 118 citations

Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins

2004 • 107 citations

Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases

2004 • 99 citations

Crystal Structure of the Alkylsulfatase AtsK: Insights into the Catalytic Mechanism of the Fe(II) α-Ketoglutarate-Dependent Dioxygenase Superfamily^,

2004 • 91 citations

The structural basis of cephalosporin formation in a mononuclear ferrous enzyme

2003 • 88 citations

Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase

2003 • 84 citations

The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity

1994 • 71 citations

Herbicide-Degrading α-Keto Acid-Dependent Enzyme TfdA: Metal Coordination Environment and Mechanistic Insights

1999 • 69 citations

Probing the Structure and Function of theEscherichia coliDNA Alkylation Repair AlkB Protein through Chemical Cross-Linking

2003 • 51 citations

The oxo/peroxo debate: a nonheme iron perspective

2004 • 41 citations