Extra-placental Expression of Vascular Endothelial Growth Factor Receptor-1, (Flt-1) and Soluble Flt-1 (sFlt-1), by Peripheral Blood Mononuclear Cells (PBMCs) in Normotensive and Preeclamptic Pregnant Women

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

2003 • 3,707 citations

Preeclampsia: An excessive maternal inflammatory response to pregnancy

1999 • 1,855 citations

Regulation of Human Placental Development by Oxygen Tension

1997 • 905 citations

Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis

1998 • 821 citations

Differential Transcriptional Regulation of the Two Vascular Endothelial Growth Factor Receptor Genes

1997 • 792 citations

Identification of a Natural Soluble Form of the Vascular Endothelial Growth Factor Receptor, FLT-1, and Its Heterodimerization with KDR

1996 • 725 citations

Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome

2002 • 637 citations

Pre-eclampsia, the Placenta and the Maternal Systemic Inflammatory Response—A Review

2003 • 630 citations

Placental Cytokines and the Pathogenesis of Preeclampsia

1997 • 476 citations

Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy

2003 • 424 citations

Regulation of Placental Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PlGF) and Soluble Flt-1 by Oxygen— A Review

2000 • 348 citations

Colocalisation of Vascular Endothelial Growth Factor and Its Flt-1 Receptor in Human Placenta

1995 • 254 citations

Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)

2001 • 252 citations

Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae

2004 • 234 citations

AT ₁ Receptor Agonistic Antibodies From Preeclamptic Patients Cause Vascular Cells to Express Tissue Factor

2000 • 233 citations

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells.

1997 • 225 citations

Release and Complex Formation of Soluble VEGFR-1 from Endothelial Cells and Biological Fluids

2000 • 217 citations

Preeclampsia and Future Cardiovascular Disease: Potential Role of Altered Angiogenesis and Insulin Resistance

2004 • 211 citations

Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells

2003 • 204 citations

Monocytes are progressively activated in the circulation of pregnant women

2002 • 175 citations

Selective Overexpression of the Hypoxia-Inducible Transcription Factor, HIF-2α, in Placentas from Women with Preeclampsia1

2001 • 153 citations

Plasma levels of vascular endothelial growth factor and its soluble receptor (SFlt-1) in essential hypertension

2001 • 148 citations

Localization of vascular endothelial growth factor and its receptor, flt, in human placenta and decidua by immunohistochemistry

1995 • 127 citations

Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae

2003 • 107 citations

Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae

2003 • 79 citations

Current Concepts in Preeclampsia

1999 • 17 citations

Expression of Vascular Endothelial Growth Factor in Peripheral Blood Cells of Preeclamptic Women

2003 • 8 citations