Release and Complex Formation of Soluble VEGFR-1 from Endothelial Cells and Biological Fluids
Data up to Jan 2025
Total Citations Per Year
Abstract
References (43)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 • 4,988 citations
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
1992 • 4,631 citations
The Biology of Vascular Endothelial Growth Factor
1997 • 4,359 citations
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 • 3,977 citations
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
1997 • 3,470 citations
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
1995 • 2,650 citations
Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
1996 • 1,908 citations
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
1992 • 1,528 citations
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.
1993 • 1,391 citations
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.
1994 • 1,104 citations
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
1998 • 1,077 citations
Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.
1990 • 982 citations
Differential Transcriptional Regulation of the Two Vascular Endothelial Growth Factor Receptor Genes
1997 • 792 citations
Identification of a Natural Soluble Form of the Vascular Endothelial Growth Factor Receptor, FLT-1, and Its Heterodimerization with KDR
1996 • 725 citations
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
1998 • 551 citations
A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.
1995 • 480 citations
Expression of Vascular Endothelial Growt Factor and Its Receptors fit and KDR in Ovarian Carcinoma
1995 • 469 citations
Molecular mechanisms of vasculogenesis and embryonic angiogenesis
1997 • 409 citations
FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines.
1992 • 285 citations
Placenta Growth Factor
2001 • 263 citations
A Heparin-Binding Form of Placenta Growth Factor (PlGF-2) is Expressed in Human Umbilical Vein Endothelial Cells and in Placenta
1993 • 245 citations
Alternative Splicing of Vascular Endothelial Growth Factor (VEGF)-R1 (FLT-1) pre-mRNA Is Important for the Regulation of VEGF Activity
1999 • 221 citations
Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1
1997 • 198 citations
Hypoxia down-regulates placenta growth factor, whereas fetal growth restriction up-regulates placenta growth factor expression: molecular evidence for "placental hyperoxia" in intrauterine growth restriction.
1999 • 197 citations
Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase.
1999 • 191 citations
AIDS-associated kaposi's sarcoma cells in culture express vascular endothelial growth factor
1992 • 164 citations
Role of VEGF receptor-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells.
1997 • 156 citations
Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells
1994 • 144 citations
Differential Binding Characteristics and Cellular Inhibition by Soluble VEGF Receptors 1 and 2
1998 • 135 citations
Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1
1998 • 124 citations
Variation in Detection of VEGF in Maternal Serum by Immunoassay and the Possible Influence of Binding Proteins
1997 • 102 citations
VEGF Receptor Subtypes KDR and FLT1 Show Different Sensitivities to Heparin and Placenta Growth Factor
1994 • 98 citations
Genomic organization of the flt-1 gene encoding for Vascular Endothelial Growth Factor (VEGF) Receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors
1998 • 91 citations
Expression and localization of placenta growth factor and PlGF receptors in human meningiomas
1999 • 85 citations
Factors affecting gas transfer across the placenta and the oxygen supply to the fetus.
1989 • 80 citations
Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells
1993 • 66 citations
Vascular endothelial growth factor is bound in amniotic fluid and maternal serum
1999 • 57 citations
Hypoxia or hyperoxia in placental insufficiency?
1997 • 56 citations
Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA
1999 • 52 citations
Functions of the VEGF Receptor-1 (FLT-1) in the Vasculature
1998 • 49 citations
Placental angiogenesis: the role of the VEGF family of proteins.
1998 • 16 citations