Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

Rapid chromatographic technique for preparative separations with moderate resolution

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Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

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1996 • 505 citations

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1999 • 312 citations

Uterine, cytoplasmic estrogen binding protein. Thermal stability and ligand dissociation rate. Assay of empty and filled sites by exchange

1973 • 288 citations

Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.

1996 • 258 citations

Comparative QSAR Analysis of Estrogen Receptor Ligands

1999 • 257 citations

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2000 • 220 citations

Photoaffinity labels for estrogen binding proteins of rat uterus

1973 • 220 citations

Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens

1999 • 218 citations

Altered Ligand Binding Properties and Enhanced Stability of a Constitutively Active Estrogen Receptor: Evidence That an Open Pocket Conformation Is Required for Ligand Interaction

1997 • 196 citations

Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles: Novel Ligands for the Estrogen Receptor

2000 • 187 citations

Structure−Activity Relationships of Selective Estrogen Receptor Modulators: Modifications to the 2-Arylbenzothiophene Core of Raloxifene

1997 • 172 citations

Equilibrium binding of estradiol by uterine cell suspensions and whole uteri in vitro

1974 • 169 citations

Estrogen Receptor Subtype-Selective Ligands: Asymmetric Synthesis and Biological Evaluation of cis- and trans-5,11-Dialkyl- 5,6,11,12-tetrahydrochrysenes

1999 • 137 citations

Selective estrogen receptor modulators (SERMs)

2011 • 112 citations

Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor

2001 • 91 citations

Hafnium(IV) Trifluoromethanesulfonate, An Efficient Catalyst for the Friedel–Crafts Acylation and Alkylation Reactions

1995 • 90 citations

Triarylpyrazoles with basic side chains

2001 • 84 citations

Different Residues of the Human Estrogen Receptor Are Involved in the Recognition of Structurally Diverse Estrogens and Antiestrogens

1997 • 76 citations

Solid-Phase Synthesis of Tetrasubstituted Pyrazoles, Novel Ligands for the Estrogen Receptor

2000 • 74 citations

Friedel–Crafts Acylation of Arenes Catalyzed by Bromopentacarbonylrhenium(I)

1995 • 65 citations

Ruthenium-catalyzed isomerization of homoallylic alcohols in water

1998 • 43 citations

Influence of new hydroxylated Triphenylethylene (TPE) derivatives on estradiol binding to uterine cytosol

1984 • 41 citations

Hydroxylated 2,3-diarylindenes: Synthesis, estrogen receptor binding affinity, and binding orientation considerations

1989 • 20 citations

Titanium Tetrachloride-Induced Three-Component Coupling Reaction of α-Haloacylsilane, Allylsilane, and Carbonyl Compound

1996 • 13 citations