Triarylpyrazoles with basic side chains

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors and

1997 • 1,148 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

1996 • 505 citations

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

1995 • 502 citations

The Estrogen Receptor β Subtype: A Novel Mediator of Estrogen Action in Neuroendocrine Systems

1998 • 431 citations

The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens

1997 • 406 citations

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

1999 • 405 citations

Peptide Antagonists of the Human Estrogen Receptor

1999 • 372 citations

Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β

1999 • 362 citations

Novel Ligands that Function as Selective Estrogens or Antiestrogens for Estrogen Receptor-α or Estrogen Receptor-β*

1999 • 312 citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones

1996 • 285 citations

Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras¹

1998 • 267 citations

Photoaffinity labels for estrogen binding proteins of rat uterus

1973 • 220 citations

Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens

1999 • 218 citations

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens

1995 • 206 citations

Altered Ligand Binding Properties and Enhanced Stability of a Constitutively Active Estrogen Receptor: Evidence That an Open Pocket Conformation Is Required for Ligand Interaction

1997 • 196 citations

Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles: Novel Ligands for the Estrogen Receptor

2000 • 187 citations

Equilibrium binding of estradiol by uterine cell suspensions and whole uteri in vitro

1974 • 169 citations

Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues: Highly Potent Selective Estrogen Receptor Modulators

1998 • 125 citations

The Medicinal Chemistry of Nonsteroidal Antiestrogens: A Review

1994 • 124 citations

Selective estrogen receptor modulators (SERMs)

2011 • 112 citations

Novel Ligands that Function as Selective Estrogens or Antiestrogens for Estrogen Receptor- or Estrogen Receptor-

1999 • 91 citations

Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor

2001 • 91 citations

Selective Estrogen Receptor Modulators (SERMs)

1970 • 87 citations

Solid-Phase Synthesis of Tetrasubstituted Pyrazoles, Novel Ligands for the Estrogen Receptor

2000 • 74 citations

Transcription Activation by the Human Estrogen Receptor Subtype (ER ) Studied with ER and ER Receptor Chimeras

1998 • 66 citations

Addition of arylmetallics to azodicarboxylates: A novel synthesis of arylhydrazines by aromatic hydrazination

1987 • 54 citations

Thermodynamic characterization of the squaramide–carboxylate interaction in squaramide receptors

2001 • 47 citations