An Interaction between Ricin and Calreticulin That May Have Implications for Toxin Trafficking

The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.

1987 • 1,153 citations

Calreticulin: one protein, one gene, many functions

1999 • 726 citations

External Labeling of Cell Surface Galactose and Galactosamine in Glycolipid and Glycoprotein of Human Erythrocytes

1973 • 698 citations

Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development

1983 • 645 citations

Calreticulin: one protein, one gene, many functions

1999 • 547 citations

Different biological properties of the two constituent peptide chains of ricin a toxic protein inhibiting protein synthesis

1973 • 464 citations

Calreticulin

1992 • 402 citations

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

1992 • 396 citations

The three-dimensional structure of ricin at 2.8 A.

1987 • 382 citations

Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.

1984 • 286 citations

Routing of internalized ricin and ricin conjugates to the Golgi complex.

1986 • 231 citations

Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol

1997 • 227 citations

Dependence of Ricin Toxicity on Translocation of the Toxin A-chain from the Endoplasmic Reticulum to the Cytosol

1999 • 204 citations

Four Intracisternal Calcium-binding Glycoproteins from Rat Liver Microsomes with High Affinity for Calcium

1989 • 200 citations

Recycling of proteins between the endoplasmic reticulum and Golgi complex

1991 • 194 citations

Toxin Entry: Retrograde Transport through the Secretory Pathway

1998 • 186 citations

KDEL Receptor (Erd2p)-mediated Retrograde Transport of the Cholera Toxin A Subunit from the Golgi Involves COPI, p23, and the COOH Terminus of Erd2p

1998 • 163 citations

Cell Surface Calreticulin Is a Putative Mannoside Lectin Which Triggers Mouse Melanoma Cell Spreading

1995 • 160 citations

Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin

1991 • 156 citations

Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect.

1991 • 152 citations

Ricin A chain utilises the endoplasmic reticulum‐associated protein degradation pathway to enter the cytosol of yeast

1999 • 150 citations

Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis.

1990 • 145 citations

The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum

1999 • 137 citations

The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes.

1993 • 137 citations

The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.

1995 • 129 citations

Toxin entry: how reversible is the secretory pathway?

1992 • 107 citations

Escherichia coli heat-labile enterotoxin. Nucleotide sequence of the A subunit gene.

1982 • 104 citations

Ricin B chain is a product of gene duplication.

1981 • 100 citations

Isolation and characterization of CAB-63, a novel calcium-binding protein.

1985 • 97 citations

Monensin and brefeldin A differentially affect the phosphorylation and sulfation of secretory proteins.

1992 • 93 citations

Precursors of ricin and Ricinus communis agglutinin

1985 • 92 citations

Different sorting of Lys-Asp-Glu-Leu proteins in rat liver.

1992 • 89 citations

Mutational analysis of the galactose binding ability of recombinant ricin B chain.

1991 • 89 citations

Studies on the galactose-binding site of ricin and the hybrid toxin man6P-ricin

1981 • 88 citations

Cell surface and intracellular functions for ricin galactose binding.

1992 • 82 citations

Biochemical Studies of Rat Liver Golgi Apparatus

1978 • 78 citations

Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells

1985 • 74 citations

Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin

1992 • 57 citations

Ribosome inactivating proteins of plants.

1991 • 50 citations

Calreticulin Biosynthesis and Processing in Human Myeloid Cells: Demonstration of Signal Peptide Cleavage and N-Glycosylation

1997 • 42 citations

Ricinus communis agglutinin B chain contains a fucosylated oligosaccharide side chain not present on ricin B chain

1985 • 21 citations

Bacterial protein toxins acting on intracellular targets.

1991 • 17 citations

Calreticulin Biosynthesis and Processing in Human Myeloid Cells: Demonstration of Signal Peptide Cleavage and N-Glycosylation

1997 • 15 citations

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