Characteristics of frontotemporal dementia patients with a Progranulin mutation

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

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HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin‐positive, tau‐negative inclusions caused by a missense mutation in the signal peptide of progranulin

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