Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

1993 • 7,941 citations

Frontotemporal lobar degeneration

1998 • 4,937 citations

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

1993 • 3,080 citations

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

1998 • 2,898 citations

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

1997 • 2,762 citations

Easy calculations of lod scores and genetic risks on small computers.

1984 • 1,526 citations

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1998 • 1,440 citations

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1998 • 1,344 citations

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

1990 • 849 citations

Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference

1997 • 626 citations

High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands

1999 • 419 citations

Frontotemporal Dementia and Corticobasal Degeneration in a Family with a P301S Mutation in Tau

1999 • 418 citations

Linkage of Familial Amyotrophic Lateral Sclerosis With Frontotemporal Dementia to Chromosome 9q21-q22

2000 • 316 citations

Straight and paired helical filaments in Alzheimer disease have a common structural unit.

1991 • 310 citations

Tau Pathology in Two Dutch Families with Mutations in the Microtubule-Binding Region of Tau

1998 • 281 citations

Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene

2000 • 264 citations

Motor Neurone Disease-inclusion Dementia

1996 • 224 citations

Phenotypic variation in hereditary frontotemporal dementia with tau mutations

1999 • 222 citations

A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)

1999 • 214 citations

FTDP-17: An early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation

1999 • 192 citations

Hereditary frontotemporal dementia is linked to chromosome 17q21—q22: A genetic and clinicopathological study of three dutch families

1997 • 175 citations

A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy

1999 • 170 citations

Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia

2001 • 158 citations

Hereditary dysphasic disinhibition dementia A frontotemporal dementia linked to 17 q21‐‐22

1998 • 145 citations

Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions

2000 • 135 citations

Semantic dementia with ubiquitin-positive tau-negative inclusion bodies

2000 • 132 citations

Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17).

2000 • 120 citations

Untangling tau-related dementia

2000 • 116 citations

DNA Damage and Activated Caspase-3 Expression in Neurons and Astrocytes: Evidence for Apoptosis in Frontotemporal Dementia

2000 • 110 citations

Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21

1997 • 92 citations

A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)

1999 • 68 citations

Ubiquitin-immunohistochemical investigation of atypical Pick's disease without Pick bodies

1998 • 39 citations

Familial frontotemporal dementia with ubiquitin inclusion bodies and without motor neuron disease

2000 • 36 citations

Chromosome 3-linked frontotemporal dementia

1998 • 35 citations

Differential distribution of presenilin-1, Bax, and Bcl-X L in Alzheimer's disease and frontotemporal dementia

1999 • 30 citations

Ubiquitin-related cytoskeletal abnormality in frontotemporal dementia: immunohistochemical and immunoelectron microscope studies

1997 • 25 citations

Search for a Mutation in the tau Gene in a Swiss Family with Frontotemporal Dementia

2000 • 15 citations