Liposomes as membrane model for study of lipid peroxidation

[30] Microsomal lipid peroxidation

1978 • 12,818 citations

Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers

1976 • 4,884 citations

Diffusion of univalent ions across the lamellae of swollen phospholipids

1965 • 4,347 citations

Techniques of lipidology (isolation, analysis and identification of lipids

1974 • 2,557 citations

The catalytic decomposition of hydrogen peroxide by iron salts

1934 • 2,483 citations

Laboratory techniques in biochemistry and molecular biology

1973 • 2,129 citations

Fluidity parameters of lipid regions determined by fluorescence polarization

1978 • 1,886 citations

Phosphatidylcholine vesicles. Formation and physical characteristics

1969 • 1,522 citations

Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

1980 • 1,491 citations

Direct observation of a free radical interaction between vitamin E and vitamin C

1979 • 1,460 citations

Formation of Malonaldehyde from Phospholipid Arachidonate during Microsomal Lipid Peroxidation

1968 • 1,421 citations

Single bilayer liposomes prepared without sonication

1973 • 1,301 citations

Mechanisms of lipid peroxide formation in animal tissues

1966 • 1,291 citations

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1980 • 1,094 citations

Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes

1979 • 1,085 citations

Lateral phase separation in phospholipid membranes

1973 • 989 citations

Phase transitions in phospholipid vesicles Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol

1973 • 986 citations

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system.

1975 • 969 citations

Formation of a thiobarbituric‐acid‐reactive substance from deoxyribose in the presence of iron salts

1981 • 830 citations

Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?

1983 • 800 citations

Phase transitions and fluidity characteristics of lipids and cell membranes

1975 • 774 citations

Phase transitions and phase separations in phospholipid membranes induced by changes in temperature, pH, and concentration of bivalent cations

1975 • 756 citations

Vitamin E: A Comprehensive Treatise

1980 • 720 citations

Liposomes as drug carriers

1977 • 664 citations

Evidence that Peroxidation of Lysosomal Membranes Is Initiated by Hydroxyl Free Radicals Produced during Flavin Enzyme Activity

1973 • 663 citations

Lipid Peroxides in Biology and Medicine

1982 • 640 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

THE REACTION BETWEEN THIOBARBITURIC ACID AND THE OXIDATION PRODUCTS OF CERTAIN LIPIDES

1948 • 635 citations

Formation and properties of thin‐walled phospholipid vesicles

1969 • 623 citations

Phospholipid model membranes. I. Structural characteristics of hydrated liquid crystals

1967 • 589 citations

The Carrier Potential of Liposomes in Biology and Medicine

1976 • 576 citations

Preparation and Use of Liposomes as Models of Biological Membranes

1974 • 567 citations

Techniques of Lipidology: isolation, analysis and identification of lipids

1974 • 540 citations

Membrane models with phospholipids

1968 • 536 citations

Ferritin and superoxide-dependent lipid peroxidation.

1985 • 532 citations

Lipid peroxide formation in microsomes. General considerations

1969 • 528 citations

Large volume liposomes by an ether vaporization method

1976 • 515 citations

Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.

1977 • 509 citations

Metal ion and metal chelate catalyzed oxidation of ascorbic acid by molecular oxygen. I. Cupric and ferric ion catalyzed oxidation

1967 • 497 citations

New method of detecting singlet oxygen production

1976 • 488 citations

Synthesis and characterization of the fluorescent products derived from malonaldehyde and amino acids

1969 • 487 citations

A calorimetric and fluorescent probe study of the gel-liquid crystalline phase transition in small, single-lamellar dipalmitoylphosphatidylcholine vesicles

1976 • 461 citations

[33] Overview of methods used for detecting lipid peroxidation

1984 • 450 citations

Ethane Evolution: A New Index of Lipid Peroxidation

1974 • 449 citations

DNA strand scission by enzymically generated oxygen radicals

1981 • 428 citations

INTERACTIONS OF LIPOSOMES WITH MAMMALIAN CELLS

1978 • 408 citations

The detection of oxidation in liposome preparations

1970 • 408 citations

Measurement and modification of forces between lecithin bilayers

1977 • 406 citations

Single bilayer vesicles prepared without sonication physico-chemical properties

1976 • 381 citations

The Role of Free Radical Reactions in Biological Systems

1976 • 374 citations

New aspects of liposomes

1976 • 368 citations

Phospholipid model membranes. II. Permeability properties of hydrated liquid crystals

1967 • 359 citations

Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles

1969 • 353 citations

Lipid Peroxidation in Mitochondrial Membrane

1980 • 348 citations

UNAMBIGUOUS EVIDENCE FOR THE PARTICIPATION OF SINGLET OXYGEN (1δ) IN PHOTODYNAMIC OXIDATION OF AMINO ACIDS

1972 • 345 citations

Microsomal Electron Transport

1973 • 327 citations

Organ chemiluminescence: noninvasive assay for oxidative radical reactions.

1980 • 322 citations

Reconstitution of biological membranes

1972 • 315 citations

The biochemical modes of action of vitamin e and selenium: A hypothesis

1973 • 310 citations

Lipid oxidation: Biologic effects and antioxidants—A review

1980 • 308 citations

Mechanisms of lipid peroxide formation in tissues Role of metals and haematin proteins in the catalysis of the oxidation of unsaturated fatty acids

1965 • 293 citations

Reconstruction of biological membranes.

1972 • 289 citations

Lipid peroxide formation in microsomes. The role of non-haem iron

1969 • 276 citations

The increase of phospholipid bilayer rigidity after lipid peroxidation

1977 • 275 citations

Formation of α-tocopherol radical and recycling of α-tocopherol by ascorbate during peroxidation of phosphatidylcholine liposomesAn electron paramagnetic resonance study

1984 • 270 citations

Role of azide in singlet oxygen reactions: Reaction of azide with singlet oxygen.

1972 • 262 citations

Lipid Bilayers and Biomembranes

1972 • 261 citations

Ion Transport and Respiratory Control in Vesicles Formed from Cytochrome Oxidase and Phospholipids

1972 • 257 citations

Lipid model membranes. Characterization of mixed phospholipid vesicles

1973 • 255 citations

Quantitative estimation of peroxidative degeneration of rat liver microsomal and mitochondrial lipids after carbon tetrachloride poisoning

1966 • 252 citations

[38] Detection of malonaldehyde by high-performance liquid chromatography

1984 • 247 citations

The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospholipids

1981 • 234 citations

Single bilayer liposomes

1971 • 215 citations

Release of enzymes from lysosomes by irradiation and the relation of lipid peroxide formation to enzyme release

1966 • 213 citations

[34] Chemical methods for the detection of lipid hydroperoxides

1984 • 210 citations

The measurement of lipid peroxidation in isolated hepatocytes

1982 • 206 citations

Aqueous Dispersions of Phosphatidylserine

1964 • 186 citations

Ultrasonic Irradiation of Some Phospholipid Sols

1962 • 182 citations

PROTECTIVE ACTION OF CAROTENOID PIGMENTS AGAINST PHOTODYNAMIC DAMAGE TO LIPOSOMES*

1973 • 179 citations

The Effect of Phospholipid Fatty Acid Composition on Membranous Enzymes in Escherichia coli

1972 • 175 citations

Lipid Peroxidation in Vivo during Vitamin E and Selenium Deficiency in the Rat as Monitored by Ethane Evolution

1977 • 175 citations

Light scattering and turbidity measurements on lipid vesicles

1976 • 175 citations

p-Nitrosodimethylaniline as an OH Radical Scavenger in Radiation Chemistry¹

1965 • 174 citations

Damage to proteins by peroxidized lipids

1963 • 174 citations

Effects of lipid peroxidation on membrane-bound enzymes of the endoplasmic reticulum

1971 • 173 citations

Biosynthesis and Metabolism of 1,4‐diaminobutane, Spermidine, Spermine, and Related Amines

1972 • 173 citations

Peroxidative and radiation damage to isolated lysosomes

1964 • 167 citations

Properties and Biological Effects of Liposomes and their uses in Pharmacology and Toxicology

1978 • 167 citations

Molecular Basis of Environmental Toxicity

1981 • 167 citations

MEASUREMENT OF AND PROTECTION FROM IN VIVO LIPID PEROXIDATION

1979 • 166 citations

Differential effect of lipid peroxidation on membrane fluidity as determined by electron spin resonance probes

1983 • 165 citations

FREE-RADICAL LIPID PEROXIDATION DAMAGE AND ITS INHIBITION BY VITAMIN E AND SELENIUM.

1965 • 164 citations

THE ROLE OF SUPEROXIDE AND SINGLET OXYGEN IN LIPID PEROXIDATION

1978 • 163 citations

Inhibition by polyamines of lipid peroxide formation in rat liver microsomes

1979 • 162 citations

Oxidation of α-tocopherol in micelles and liposomes by the hydroxyl, perhydroxyl, and superoxide free radicals

1983 • 162 citations

Inhibition of lipid peroxidation in isolated inner membrane of rat liver mitochondria by superoxide dismutase

1973 • 161 citations

Phospholipid vesicles (liposomes) as models for biological membranes: Their properties and interactions with cholesterol and proteins

1974 • 161 citations

Oxidation of arachidonic acid in micelles by superoxide and hydrogen peroxide.

1981 • 160 citations

Lipid Peroxidation of Rat‐Liver Microsomes

1973 • 156 citations

The effect of ultrasonic irradiation on the chemical structure of egg lecithin

1971 • 153 citations

Effect of ferrous ion and ascorbate-induced lipid peroxidation on liposomal membranes

1981 • 146 citations

Microsomal lipid peroxidation causes an increase in the order of the membrane lipid domain

1982 • 145 citations

The introduction of enzymes into cells by means of liposomes.

1978 • 142 citations

Thiol-dependent lipid peroxidation

1982 • 142 citations

The destruction of —SH groups of proteins and amino acids by peroxides of unsaturated fatty acids

1962 • 141 citations

A cholate‐dilution procedure for the reconstitution of the Ca⁺⁺ pump, ³²P_i—ATP exchange, and oxidative phosphorylation

1975 • 141 citations

Protein-liposome interactions and their relevance to the structure and function of cell membranes

1976 • 139 citations

Copper(II)‐catalyzed lipid peroxidation in liposomes and erythrocyte membranes

1982 • 138 citations

Antioxidative effect of α-tocopherol incorporation into lecithin liposomes on ascorbic acid-Fe2+-induced lipid peroxidation

1981 • 138 citations

The role of superoxide and hydroxyl radicals in phospholipid peroxidation catalysed by iron salts

1982 • 136 citations

Microsomal lipid peroxidation. I. Characterization of the role of iron and NADPH.

1980 • 135 citations

Radiation Effects on Membranes: I. Vitamin E Deficiency and Lipid Peroxidation

1979 • 134 citations

Chapter 4 Lipid Vesicles as Carriers for Introducing Biologically Active Materials into Cells

1976 • 131 citations

Oxidation by Molecular Oxygen. II. The Oxygen Atom Transfer Mechanism for Mixed-Function Oxidases and the Model for Mixed-Function Oxidases

1964 • 130 citations

Characterization of dimyristoylphosphatidylcholine vesicles and their dimensional changes through the phase transition: molecular control of membrane morphology

1978 • 130 citations

Radioprotective effect of superoxide dismutase on model phospholipid membranes

1976 • 129 citations

Free radical reactions and their importance in biochemical systems.

1973 • 129 citations

Dose-rate and Oxygen Effects in Models of Lipid Membranes: Linoleic Acid

1977 • 128 citations

Oxidative interactions between haemoglobin and membrane lipid. A liposome model

1984 • 126 citations

Alterations in erythrocyte membrane fluidity by phenylhydrazine-induced peroxidation of lipids

1981 • 122 citations

Interactions of tocopherols and ubiquinones with monolayers of phospholipids

1977 • 119 citations

Protection of Liposomal Lipids against Radiation Induced Oxidative Damage

1979 • 118 citations

Lipid peroxidation of rat liver microsomes

1980 • 118 citations

Lipid oxidation in biological membranes

1970 • 117 citations

Effect of unsaturated fatty acids and their peroxides on enzymes

1961 • 112 citations

Role of Cholesterol in Biomembranes and Related Systems

1975 • 111 citations

Peroxidative Hemolysis of Red Blood Cells from Patients with Abetalipoproteinemia (Acanthocytosis)*

1967 • 109 citations

Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats

1973 • 105 citations

Antioxidant activities of tocopherols on Fe²⁺‐ascorbate‐induced lipid peroxidation in lecithin liposomes

1982 • 104 citations

Reactions of Radicals with Lecithin Bilayers

1978 • 103 citations

Chemistry of singlet oxygen. 30. The unstable primary product of tocopherol photooxidation

1979 • 102 citations

Stable lipid peroxidation products in human skin: detection, ultraviolet light-induced increase, pathogenic importance

1976 • 101 citations

Relationship between malondialdehyde production and arachidonate consumption during NADPH-supported microsomal lipid peroxidation

1982 • 99 citations

The multiple effects of ethylenediaminetetraacetate in several model lipid peroxidation systems

1982 • 99 citations

Protective Agents in Cancer

1983 • 98 citations

Inhibition of tumor glycolysis by hydrogen peroxide formed from autoxidation of unsaturated fatty acids

1963 • 95 citations

Intracellular mechanisms for the decomposition of a lipid peroxide. II. Decomposition of a lipid peroxide by subcellular fractions

1969 • 94 citations

Effects of in vivo hyperoxia on erythrocytes. 3. In vivo peroxidation of erythrocyte lipid.

1966 • 93 citations

Radiation-induced Lipid Peroxidation and Membrane Permeability in Liposomes

1980 • 92 citations

Oxidation by superoxide of tocopherols dispersed in aqueous media with deoxycholate

1980 • 88 citations

Superoxide dependent lipid peroxidation.

1981 • 87 citations

Ultraviolet- and Sunlight-Induced Lipid Peroxidation in Liposomal Membrane

1980 • 86 citations

Structural Properties of Lipids and Their Functional Roles in Biological Membranes

1983 • 86 citations

Decreased [3H]serotonin and [3H]spiperone binding consequent to lipid peroxidation in rat cortical membranes

1982 • 81 citations

A Spin-label Study of the Effect of Gamma Radiation on Erythrocyte Membrane. Influence of Lipid Peroxidation on Membrane Structure

1979 • 79 citations

The effect of concentration on the antioxidant effectiveness of α-tocopherol in lipid peroxidation induced by superoxide free radicals

1985 • 79 citations

Water permeability of phospholipid vesicles

1970 • 79 citations

Structural changes in microsomal suspensions

1965 • 78 citations

Initiation of lipid peroxidation by a reduced metal ion

1962 • 77 citations

Degradation of linoleic acid hydroperoxides by a cysteine FeCl3 catalyst as a model for similar biochemical reactions

1981 • 75 citations

The Irradiation-Induced Autoxidation of Linoleic Acid

1952 • 75 citations

Equilibrium and metastable states in lecithin films

1977 • 74 citations

The effect of lead on hemoglobin-catalyzed lipid peroxidation

1981 • 73 citations

On the Sonochemical Formation of Hydrogen Peroxide in Water

1964 • 71 citations

Polyamine binding to phospholipid vesicles and inhibition of lipid peroxidation

1984 • 68 citations

RETINAL SENSITIZED PHOTODYNAMIC DAMAGE TO LIPOSOMES

1978 • 66 citations

Effect of hydrogen peroxide on the initiation of microsomal lipid peroxidation

1983 • 65 citations

Comparison of Spectrophotometric and Spectrophotofluorometric Methods for the Determination of Malonaldehyde.

1963 • 63 citations

Low Oxygen Enhancement Ratios for Radiosensitive Bacterial Strains, and the Probable Interaction of Two Types of Primary Lesion

1968 • 63 citations

Phospholipid reactivation of the purified plasma membrane ATPase of yeast.

1980 • 61 citations

The effect of chronic ethanol consumption on temperature-dependent physical properties of liver mitochondrial membranes

1982 • 59 citations

Effects of membrane-stabilizing agents, cholesterol and cepharanthin, on radiation-induced lipid peroxidation and permeability in liposomes

1982 • 59 citations

Correlation of Oxygen Consumption with Swelling and Lipid Peroxide Formation when Mitochondria Are Treated with the Swelling-inducing Agents Fe²⁺, Glutathione, Ascorbate, or Phosphate^*

1964 • 59 citations

Radiation Effects on Membranes: II. A Comparison of the Effects of X Irradiation and Ozone Exposure with Respect to the Relation of Antioxidant Concentration and the Capacity for Lipid Peroxidation

1980 • 59 citations

Permeability changes induced by peroxidation in liposomes prepared from human erythrocyte lipids

1974 • 58 citations

The Estimation and Identification of Organic Peroxides

1963 • 58 citations

Studies of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes: Increased Lysis and Lipid Peroxide Formation by Hydrogen Peroxide*

1967 • 54 citations

Radical addition of linoleic hydroperoxides to α‐tocopherol or the analogous hydroxychroman

1972 • 54 citations

Sulfite‐induced lipid peroxidation

1981 • 54 citations

Radiation-induced Lipid Peroxidation and Membrane-bound Enzymes in Liver Microsomes

1980 • 53 citations

Relation of lipid peroxidation to loss of cations trapped in liposomes

1971 • 53 citations

The effects of 3-methylcholanthrene and phenobarbital induction on the structure of the rat liver endoplasmic reticulum

1974 • 52 citations

A reaction between the superoxide free radical and lipid hydroperoxide in sodium linoleate micelles

1982 • 50 citations

SKIN CANCER AND ULTRAVIOLET RADIATION

1978 • 49 citations

A model for the effect of lipid oxidation on diphenylhexatriene fluorescence in phospholipid vesicles

1981 • 48 citations

COMPARATIVE ASPECTS OF SEVERAL MODEL LIPID PEROXIDATION SYSTEMS

1982 • 48 citations

Effects of dietary antioxidants on in vivo lipid peroxidation in the rat as measured by pentane production

1978 • 46 citations

A radioprotective effect of vitamin C observed in Chinese hamster ovary cells

1977 • 46 citations

Monosialoganglioside liposome-entrapped enzyme uptake by hepatic cells

1977 • 46 citations

Effect of a phase transition on the binding of 1-anilino-8-naphthalenesulfonate to phospholipid membranes

1976 • 43 citations

Formation of ∙ OH and ∙ H in Aqueous Solutions by Ultrasound Using Clinical Equipment

1983 • 43 citations

A radical scavenging reaction of α‐tocopherol with methyl radical

1976 • 41 citations

Lipid peroxidation in hemoglobin-containing liposomes. Effects of membrane phospholipid composition and cholesterol content

1986 • 41 citations

Formation of .OH and .H in aqueous solutions by ultrasound using clinical equipment.

1983 • 41 citations

Radiation-induced Generation and Properties of Lipid Hydroperoxide in Liposomes

1983 • 41 citations

Reconstitution Studies on the Involvement of Radiation-induced Lipid Peroxidation in Damage to Membrane Enzymes

1983 • 40 citations

Comparison of the Radiosensitivity of Unsaturated Fatty Acids, Structured as Micelles or Liposomes, under Different Experimental Conditions

1982 • 39 citations

DMSO Does Not Protect Against Hydroxyl Radical Induced Peroxidation in Model Membranes

1981 • 39 citations

The antioxidant activity of alpha-tocopherol-bovine serum albumin complex in micellar and liposome autoxidations.

1985 • 39 citations

Radiation-induced Lipid Peroxidation and Membrane-bound Enzymes in Liver Microsomes

1980 • 35 citations

Increase in superoxide dismutase activity concomitant with a decrease in lipid peroxidation of liver during post partum development

1977 • 35 citations

MODELS RELATING ULTRAVIOLET LIGHT AND NON‐MELANOMA SKIN CANCER INCIDENCE*

1978 • 34 citations

Determination of lipid conjugated dienes with tetracyano‐ethylene‐¹⁴C: Significance for study of the pathology of lipid peroxidation

1977 • 34 citations

Superoxide-dependent lipid peroxidation. Problems with the use of catalase as a specific probe for fenton-derived hydroxyl radicals

1983 • 33 citations

Promotion of Radiation Peroxidation in Models of Lipid Membranes by Caesium and Rubidium Counter-ions: Micellar Linoleic and Linolenic Acids

1978 • 31 citations

Effect of Ultra-violet Radiation on the Liposomal Membrane

1978 • 31 citations

ChemInform Abstract: CHEMISTRY OF SINGLET OXYGEN. 30. THE UNSTABLE PRIMARY PRODUCT OF TOCOPHEROL PHOTOOXIDATION

1979 • 31 citations

COMPARATIVE PROPERTIES AND METHODS OF PREPARATION OF LIPID VESICLES

1980 • 30 citations

Effects on adenylate cyclase activities of unsaturated fatty acid incorporation into rat liver plasma membrane phospholipids specific modulation by linoleate

1980 • 30 citations

Alkane formation during liver microsomal lipid peroxidation

1982 • 28 citations

Membrane fluidity and drug metabolism in liver microsomes of lean, obob and dbdb mice

1980 • 28 citations

Radiation-induced Changes of Liposomes and Lecithin in Non-aqueous Media

1981 • 27 citations

Ultrasonic radiation induced lipid peroxidation in liposomal membrane

1986 • 21 citations

Dose-rate effects in biomembranes.

1979 • 21 citations

Effects of Antioxidants on Lipid Peroxide Formation in Irradiated Synthetic Diets

1980 • 20 citations

A New Color Reaction of Anthrone with Malonaldehyde and Other Aliphatic Aldehydes.

1963 • 19 citations

A Study of the Peroxidation of Fatty Acid Micelles Promoted by Ionizing Radiation, Hydrogen Peroxide and Ascorbate

1981 • 19 citations

Differential effecs of etiocholanolone on phospholipid/cholesterol structures containing either testosterone or estradiol

1968 • 18 citations

The reaction of a α-tocopherol model compound with KO2, a new oxidation product of 6-hydroxy-2,2,5,7,8-pentamethylchroman

1977 • 16 citations

Effects of oxygen on ferrous sulphate induced lipid peroxidation in liposomal membrane.

1985 • 14 citations

Lipid peroxidation by ultraviolet light and high energy? particles from a cyclotron

1983 • 11 citations

Influence of Oxygen on the Radiochemical Inactivation of the Microsomal Monooxygenase Complex

1981 • 10 citations

Radiosensitivity of NAD Glycohydrolase in the Nuclear Membrane of Fast Growing Mouse Liver

1975 • 9 citations

The Effects of Ionizing Radiation on the Peroxide Content of a Pure Polyunsaturated Lipid Dispersion and of Lipids and Membranes Derived fromAcholeplasma Laidlawii

1984 • 8 citations

Interaction of X-irradiation and drugs on the activity of membrane bound enzymes

1975 • 7 citations

Peroxidation of the Dried Thin Film of Lipid by High-Energy Alpha Particles from a Cyclotron

1984 • 7 citations

Effects of oxygen on ascorbic acid-induced lipid peroxidation in liposomal membrane.

1984 • 6 citations