Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N′-nitro-N-nitrosoguanidine

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Molecular and environmental aspects of mutagenesis

1976 • 444 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

Formation and Metabolism of Alkylated Nucleosides: Possible Role in Carcinogenesis by Nitroso Compounds and Alkylating Agents

1977 • 304 citations

Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

1982 • 287 citations

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1982 • 283 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines

1980 • 218 citations

The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems

1979 • 211 citations

Sister Chromatid Exchanges

1980 • 203 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

1982 • 172 citations

Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

1979 • 160 citations

Quantitation of the adaptive response to alkylating agents

1979 • 145 citations

Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichiacoli

1980 • 141 citations

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines.

1981 • 121 citations

Removal of O6-methylguanine from DNA by human liver fractions.

1982 • 102 citations

Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.

1979 • 101 citations

Effect of chronic treatment of rats with dimethylnitrosamine on the removal of O6-methylguanine from DNA.

1980 • 99 citations

Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.

1981 • 89 citations

Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen.

1982 • 84 citations

Relative mutagenicity of antineoplastic drugs and other alkylating agents in V79 chinese hamster cells, independence of cytotoxic and mutagenic responses

1980 • 80 citations

The stability of methylated purines and of methylphosphotriesters in the DNA of V79 cells after treatment with N-methyl-N-nitrosourea

1979 • 80 citations

DNA Repair

1981 • 78 citations

A common mechanism for repair of O6-methylguanine and O6-ethylguanine in DNA

1982 • 76 citations

Abilities of extracts of human lymphocytes to remove O6-methylguanine from DNA

1982 • 62 citations

Enhanced survival and reduced mutation and aberration frequencies induced in 79 Chinese hamster cells pre-exposed to low levels of methylating agents

1982 • 58 citations

Pretreatment with acetylaminofluorene enhances the repair of O6-methylguanine in DNA

1979 • 57 citations

Alkylation-induced sister-chromatic exchanges correlate with reduced cell survival, not mutations

1982 • 41 citations

Adaptive increase of O⁶-methlguanine-acceptor protein in HeLa cells following N-methyl-N′-nitro-N-nitrosoguanidine treatment

1982 • 38 citations

A chromatin factor in rat liver which destroys O⁶‐ethylguanine in DNA

1980 • 36 citations

Pretreatment of Chinese hamster V79 cells with MNU increases survival without affecting DNA repair or mutagenicity

1981 • 34 citations

Changes in O6-methylguanine disappearance from rat liver dna during chronic dimethylnitrosamine administration

1980 • 30 citations

Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA

1979 • 30 citations

Studies on adaptation of V79 Chinese hamster cells to low doses of methylating agents

1983 • 26 citations

Effect of acute doses of 2-acetylaminofluorene on the capacity of rat liver to repair methylated purines in DNA in vivo and in vitro.

1982 • 24 citations