Removal of O6-methylguanine from DNA by human liver fractions.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Genetic studies of the lac repressor

1977 • 610 citations

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1974 • 495 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

1980 • 371 citations

Formation and Metabolism of Alkylated Nucleosides: Possible Role in Carcinogenesis by Nitroso Compounds and Alkylating Agents

1977 • 304 citations

N-nitroso alkylating agents: formation and persistence of alkyl derivatives in mammalian nucleic acids as contributing factors in carcinogenesis.

1979 • 276 citations

Naturally Occurring Carcinogens, Mutagens and Modulators of Carcinogenesis

1980 • 242 citations

Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification

1980 • 234 citations

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines

1981 • 183 citations

Drug metabolism in human liver in vitro: Establishment of a human liver bank

1980 • 176 citations

Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts.

1981 • 142 citations

Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichiacoli

1980 • 141 citations

A system in mouse liver for the repair of O⁶-methylguanine lesions in methylated DNA

1981 • 137 citations

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines.

1981 • 121 citations

Molecular and Cellular Aspects of Carcinogen Screening Tests

1981 • 113 citations

Formation and subsequent removal of O6-methylguanine from deoxyribonucleic acid in rat liver and kidney after small doses of dimethylnitrosamine

1978 • 105 citations

Effect of chronic treatment of rats with dimethylnitrosamine on the removal of O6-methylguanine from DNA.

1980 • 99 citations

Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.

1981 • 89 citations

Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis

1981 • 88 citations

Enzymatic removal of O6-methylguanine from DNA by mammalian cell extracts

1978 • 83 citations

Effect of partial hepatectomy on removal of O6-methylguanine from alkylated DNA by rat liver extracts

1981 • 81 citations

Metabolism of Dimethylnitrosamine by Human Liver Slices in Vitro

1970 • 76 citations

Time course of O6-methylguanine removal from DNA of N-methyl-N-nitrosourea-treatedhuman fibroblasts

1981 • 69 citations

Methylated purines in human liver DNA after probable dimethylnitrosamine poisoning.

1980 • 65 citations

Alkylation of nucleic acids and metabolism of small doses of dimethylnitrosamine in the rat.

1981 • 57 citations

Stimulation of transfer of methyl groups from O⁶-methylguanine in DNA to protein by rat liver extracts in response to hepatotoxins

1981 • 54 citations

Formation and loss of alkylated purines from DNA of hamster liver after administration of dimethylnitrosamine.

1979 • 53 citations

Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.

1981 • 43 citations

Selectivity of the excision of alkylation products in a xeroderma pigmentosum-derived lymphoblastoid line

1979 • 42 citations

The absorption and metabolism in rats of small oral doses of dimethylnitrosamine. Implication for the possible hazard of dimethylnitrosamine in human food

1977 • 40 citations

Mode of action of methylating carcinogens: comparative studies of murine and human cells

1981 • 37 citations

Alkylation of DNA and carcinogenicity ofN‐nitroso compounds

1980 • 16 citations

The Leeuwenhoek Lecture, 1978 Bacteria as proper subjects for cancer research

1980 • 11 citations