μ-Opioid and GABAB receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Receptor-effector coupling by G proteins

1990 • 1,117 citations

Classes of Calcium Channels in Vertebrate Cells

1989 • 1,082 citations

Roles of N-Type and Q-Type Ca ²⁺ Channels in Supporting Hippocampal Synaptic Transmission

1994 • 964 citations

Exocytotic Ca2+ channels in mammalian central neurons

1995 • 920 citations

P-type calcium channels blocked by the spider toxin ω-Aga-IVA

1992 • 877 citations

Voltage-dependent modulation of N-type calcium channels by G-protein β γsubunits

1996 • 822 citations

Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons

1995 • 819 citations

Modulation of Ca2+ channels βγ G-protein py subunits

1996 • 805 citations

P-type calcium channels in rat central and peripheral neurons

1992 • 788 citations

Modulation of ion-channel function by G-protein-coupled receptors

1994 • 764 citations

Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons

1989 • 667 citations

GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels

1986 • 666 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

Molecular diversity of voltage-dependent Ca2+ channels

1991 • 600 citations

GABA_B Receptor Pharmacology

1993 • 591 citations

Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents

1991 • 576 citations

Crosstalk between G proteins and protein kinase C mediated by the calcium channel α1 subunit

1997 • 491 citations

A new conus peptide ligand for mammalian presynaptic Ca2+ channels

1992 • 487 citations

Calcium Channels in Vertebrate Cells

1990 • 454 citations

Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid

1991 • 448 citations

Direct binding of G-protein βλ complex to voltage-dependent calcium channels

1997 • 441 citations

Distinctive biophysical and pharmacological properties of class A (BI) calcium channel α1 subunits

1993 • 431 citations

Ca2+ channels in rat central and peripheral neurons: High-threshold current resistant to dihydropyridine blockers and ω-conotoxin

1991 • 423 citations

α-Adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium-channel gating

1989 • 417 citations

Selectivity in Signal Transduction Determined by γ Subunits of Heterotrimeric G Proteins

1993 • 393 citations

Different β-subunits determine G-protein interaction with transmembrane receptors

1992 • 390 citations

Presynaptic inhibition in the hippocampus

1993 • 354 citations

Drug receptors and the inhibition of nerve cells

1989 • 308 citations

Exocytotic Ca2+ channels in mammalian central neurons

1995 • 293 citations

GABAB Receptor Inhibition of P-type Ca2+ Channels in Central Neurons

1993 • 274 citations

Determinants of the G protein-dependent opioid modulation of neuronal calcium channels.

1996 • 272 citations

D₂Dopamine Receptors Reduce N-Type Ca²⁺Currents in Rat Neostriatal Cholinergic Interneurons Through a Membrane-Delimited, Protein-Kinase-C-Insensitive Pathway

1997 • 258 citations

A diffusible second messenger mediates one of the pathways coupling receptors to calcium channels in rat sympathetic neurons

1991 • 221 citations

Mechanism of mu‐opioid receptor‐mediated presynaptic inhibition in the rat hippocampus in vitro.

1993 • 216 citations

Modulation of Ca2+ channels by protein kinase C in rat central and peripheral neurons: Disruption of G protein-mediated inhibition

1993 • 211 citations

The G.L. Brown Prize Lecture. Voltage‐dependent calcium channels and their modulation by neurotransmitters and G proteins

1995 • 207 citations

2-Hydroxy-saclofen: an improved antagonist at central and peripheral GABAB receptors

1988 • 202 citations

Voltage-sensitive Ca2+ channels.

1992 • 199 citations

Pertussis toxin and voltage dependence distinguish multiple pathways modulating calcium channels of rat sympathetic neurons

1992 • 192 citations

GABAB receptor‐mediated inhibition of Ca2+ currents and synaptic transmission in cultured rat hippocampal neurones.

1991 • 178 citations

Modulation of vertebrate neuronal calcium channels by transmitters

1991 • 175 citations

Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons.

1991 • 174 citations

μ and δ opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells

1993 • 174 citations

GABAB receptor‐mediated presynaptic inhibition in guinea‐pig hippocampus is caused by reduction of presynaptic Ca2+ influx.

1995 • 157 citations

Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals

1993 • 150 citations

Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation

1991 • 145 citations

Opioid receptors modulate diverse types of calcium channels in the nucleus tractus solitarius of the rat

1994 • 140 citations

Transmitter-mediated inhibition of N-type calcium channels in sensory neurons involves multiple GTP-binding proteins and subunits

1995 • 136 citations

mu-Opioid receptor activation reduces multiple components of high- threshold calcium current in rat sensory neurons

1995 • 123 citations

μ-Opioid-receptor-mediated inhibidon of the N-type calcium-channel current

1991 • 120 citations

Activation and modulation of neuronal K+ channels by GABA

1992 • 117 citations

Brain stem localization of vagal preganglionic neurons

1981 • 114 citations

GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G(0): antisense oligonucleotide studies.

1993 • 110 citations

mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein

1994 • 106 citations

Presynaptic inhibition of calcium-dependent and -independent release elicited with ionomycin, gadolinium, and alpha-latrotoxin in the hippocampus

1996 • 104 citations

T-type calcium channels: heterogeneous expression in rat sensory neurons and selective modulation by phorbol esters

1990 • 104 citations

Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents.

1990 • 104 citations

Expression of the μ‐Opioid Receptor in CHO Cells: Ability of μ‐Opioid Ligands to Promote α‐Azidoanilido[³²P]GTP Labeling of Multiple G Protein α Subunits

1995 • 102 citations

Opioid receptor selectivity of dynorphin gene products.

1984 • 99 citations

μ‐Opioid Receptor Stimulation of Inositol (1,4,5)Trisphosphate Formation via a Pertussis Toxin‐Sensitive G Protein

1994 • 95 citations

Fast, local signal transduction between the mu opioid receptor and Ca2+ channels

1995 • 88 citations

Go transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neurons

1993 • 85 citations

μ-opioids activate phospholipase C in SH-SY5Y human neuroblastoma cells via calcium-channel opening

1995 • 81 citations

Distinct, convergent second messenger pathways modulate neuronal calcium currents

1993 • 78 citations

Opioids act at μ-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance

1990 • 71 citations

Multiple Gi protein subtypes regulate a single effector mechanism.

1991 • 67 citations

Selective G-protein regulation of neuronal calcium channels.

1996 • 64 citations

Selective G-Protein Regulation of Neuronal Calcium Channels

1996 • 56 citations

GABAB agonists modulate a transient potassium current in cultured mammalian hippocampal neurons

1990 • 56 citations

Effects of met-enkephalin on GABAergic spontaneous miniature IPSPs in organotypic slice cultures of the rat hippocampus

1993 • 55 citations

The cyclic AMP‐dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones.

1990 • 50 citations

Molecular Diversity of Voltage‐Dependent Calcium Channel

1993 • 50 citations

Inhibition by bradykinin of voltage-activated barium current in a rat dorsal root ganglion cell line: role of protein kinase C

1991 • 43 citations

Activators of protein kinase C selectively enhance inactivation of a calcium current component of cultured sensory neurons in a pertussis toxin-sensitive manner

1989 • 33 citations

GABAB receptors modulate an omega-conotoxin-sensitive calcium current that is required for synaptic transmission in the Xenopus embryo spinal cord

1994 • 32 citations

Kinetic analysis of the GABAB‐mediated inhibition of the high‐threshold Ca2+ current in cultured rat sensory neurones.

1992 • 30 citations

Selectivity of the effects of guanosine-5'-O-(2-thiodiphosphate) on agonist inhibition of the M-current in amphibian sympathetic neurons

1991 • 28 citations

Regulation by GTP and its stable thiol derivatives of calcium current components in rat nodose ganglion neurons.

1990 • 19 citations

Interaction of convergent pathways that inhibit N-type calcium currents in sensory neurons

1995 • 18 citations