Mechanism of mu‐opioid receptor‐mediated presynaptic inhibition in the rat hippocampus in vitro.

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Quantal components of the end‐plate potential

1954 • 2,182 citations

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

1989 • 905 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1985 • 736 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons

1979 • 610 citations

Comparison of the actions of adenosine at pre‐ and postsynaptic receptors in the rat hippocampus in vitro.

1992 • 486 citations

A synthetic enkephalin analogue with prolonged parenteral and oral analgesic activity

1977 • 395 citations

Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus

1992 • 369 citations

Pre- and postsynaptic GABAB receptors in the hippocampus have different pharmacological properties

1988 • 368 citations

The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation

1993 • 342 citations

Modulation of ion channel activity: a key function of the protein kinase C enzyme family.

1989 • 338 citations

Enkephalin blocks inhibitory pathways in the vertebrate CNS

1980 • 334 citations

Bremazocine: A potent, long-acting opiate kappa-agonist

1980 • 314 citations

Drug receptors and the inhibition of nerve cells

1989 • 308 citations

Enkephalin hyperpolarizes interneurones in the rat hippocampus.

1988 • 296 citations

On the potassium conductance increased by opioids in rat locus coeruleus neurones.

1985 • 265 citations

Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons

1992 • 261 citations

The regulation of quantal size

1991 • 247 citations

Pertussis toxin blocks the outward currents evoked by opiate and α2-agonists in locus coeruleus neurons

1986 • 241 citations

On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings.

1984 • 214 citations

Development of the hippocampus in vitro: Cell types, synapses and receptors

1984 • 210 citations

Inhibition of quantal transmitter release in the absence of calcium influx by a G protein-linked adenosine receptor at hippocampal synapses

1992 • 201 citations

Distribution of opiate receptor subtypes and enkephalin and dynorphin immunoreactivity in the hippocampus of squirrel, guinea pig, rat, and hamster

1987 • 180 citations

Inward rectification of resting and opiate-activated potassium currents in rat locus coeruleus neurons

1988 • 169 citations

Mu and kappa opioids inhibit transmitter release by different mechanisms.

1985 • 161 citations

Presynaptic calcium and serotonin-mediated enhancement of transmitter release at crayfish neuromuscular junction

1991 • 158 citations

Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea‐pig submucosal neurones.

1990 • 146 citations

Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation

1991 • 145 citations

Presynaptic inhibitory action of enkephalin on excitatory transmission in superficial dorsal horn of rat spinal cord.

1992 • 135 citations

Opiate- and alpha 2-adrenoceptor-induced hyperpolarizations of locus ceruleus neurons in brain slices: reversal by cyclic adenosine 3':5'- monophosphate analogues

1985 • 132 citations

Agonists at μ‐opioid, M₂ ‐muscarinic and GABA_B ‐receptors increase the same potassium conductance in rat lateral parabrachial neurones

1988 • 130 citations

Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus

1991 • 124 citations

Facilitatory and inhibitory transmitters modulate spontaneous transmitter release at cultured Aplysia sensorimotor synapses.

1990 • 124 citations

μ-Opioid-receptor-mediated inhibidon of the N-type calcium-channel current

1991 • 120 citations

A neuromodulator of synaptic transmission acts on the secretory apparatus as well as on ion channels

1989 • 117 citations

The ionic mechanisms underlying opioid actions

1988 • 101 citations

Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors

1986 • 98 citations

Excitatory action of opioid peptides and opiates on cultured hippocampal pyramidal cells

1980 • 97 citations

The Wellcome Foundation Lecture, 1982 Opioid peptides and their receptors

1985 • 96 citations

Serotonin attenuates a slow inhibitory postsynaptic potential in rat hippocampal neurons

1990 • 85 citations

Quantitative autoradiographic analysis of Mu and delta opioid binding sites in the rat hippocampal formation

1986 • 80 citations

Anatomical and Physiological Properties of GABAergic Neurotransmission in Organotypic Slice Cultures of Rat Hippocampus

1989 • 67 citations

Phorbol Esters Increase GTP‐Dependent Adenylate Cyclase Activity in Rat Brain Striatal Membranes

1986 • 39 citations

Evidence for μ opiate receptors on inhibitory terminals in area CA1 of rat hippocampus

1991 • 35 citations

Involvement of μ-receptors in the opioid-induced generation of bursting discharges in hippocampal pyramidal cells

1981 • 21 citations

Bremazocine differentially antagonizes responses to selective μ and δ opioid receptor agonists in rat hippocampus

1987 • 19 citations