Role of heparan sulfate proteoglycans in cell–cell signaling in Drosophila

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function

1998 • 1,623 citations

FGFs, heparan sulfate and FGFRs: complex interactions essential for development

2000 • 771 citations

Specificities of heparan sulphate proteoglycans in developmental processes

2000 • 706 citations

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1998 • 505 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

1998 • 453 citations

The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate

1998 • 425 citations

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1999 • 393 citations

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1998 • 377 citations

Hedgehog Movement Is Regulated through tout velu–Dependent Synthesis of a Heparan Sulfate Proteoglycan

1999 • 367 citations

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development

1999 • 367 citations

The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

1996 • 331 citations

Wingless Repression of Drosophila frizzled 2 Expression Shapes the Wingless Morphogen Gradient in the Wing

1998 • 331 citations

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.

1996 • 307 citations

The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis

1997 • 290 citations

The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila

1995 • 271 citations

Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

1997 • 257 citations

dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp

1997 • 241 citations

Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity

1998 • 208 citations

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

1997 • 196 citations

Zygotic Lethal Mutations With Maternal Effect Phenotypes in Drosophila melanogaster. II. Loci on the Second and Third Chromosomes Identified by P-Element-Induced Mutations

1996 • 174 citations

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase.

1992 • 163 citations

Drosophila wingless: A paradigm for the function and mechanism of Wnt signaling

1994 • 157 citations

UDP‐glucose dehydrogenase from bovine liver: Primary structure and relationship to other dehydrogenases

1994 • 60 citations