Activation-associated phenotype of CD3+ T cells in acute graft-versus-host disease

1994 Consensus Conference on Acute GVHD Grading.

1995 • 4,743 citations

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes.

1992 • 592 citations

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement

1983 • 365 citations

Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation

1997 • 338 citations

Reconstitution of the T-Cell Compartment After Bone Marrow Transplantation: Restoration of the Repertoire by Thymic Emigrants

1998 • 223 citations

Utility of flow cytometric detection of CD69 expression as a rapid method for determining poly- and oligoclonal lymphocyte activation

1996 • 198 citations

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation.

1997 • 193 citations

Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease.

1994 • 187 citations

Cd40 Ligand (Cd154) Triggers a Short-Term Cd4+ T Cell Activation Response That Results in Secretion of Immunomodulatory Cytokines and Apoptosis

2000 • 187 citations

Selective depletion of myelin–reactive T cells with the anti–OX–40 antibody ameliorates autoimmune encephalomyelitis

1996 • 159 citations

Ligation of 4-1BB (CDw137) Regulates Graft-Versus-Host Disease, Graft-Versus-Leukemia, and Graft Rejection in Allogeneic Bone Marrow Transplant Recipients

2001 • 147 citations

Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

2004 • 143 citations

Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-gamma production.

1998 • 106 citations

Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation

2000 • 105 citations

CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans

2003 • 100 citations

Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development: CTLA4Ig prevents both acute and chronic GVHD development but reverses only chronic GVHD.

1996 • 91 citations

Immune reconstitution after haematopoietic cell transplantation in children: immunophenotype analysis with regard to factors affecting the speed of recovery

2002 • 88 citations

Differential Expression of Fas and Fas Ligand in Acute and Chronic Graft-Versus-Host Disease: Up-Regulation of Fas and Fas Ligand Requires CD8+ T Cell Activation and IFN-γ Production

1998 • 87 citations

Expression of the T-Cell Activation Antigen, OX-40, Identifies Alloreactive T Cells in Acute Graft-Versus-Host Disease

1997 • 83 citations

REDUCTION IN THE SEVERITY OF GRAFT-VERSUS-HOST DISEASE AND INCREASED SURVIVAL IN ALLOGENEIC MICE BY TREATMENT WITH MONOCLONAL ANTIBODIES TO CELL ADHESION ANTIGENS LFA-lα AND MALA-2

1991 • 64 citations

The generation of T cell memory: a review describing the molecular and cellular events following OX40 (CD134) engagement

2004 • 55 citations

Correlation of peripheral blood OX40+(CD134+) T cells with chronic graft-versus-host disease in patients who underwent allogeneic hematopoietic stem cell transplantation

2001 • 47 citations

Distinctive response of naïve lymphocytes from cord blood to primary activation via TCR

2003 • 37 citations

Prevention of graft-versus-host disease in high risk patients by depletion of CD4+ and reduction of CD8+ lymphocytes in the marrow graft

1999 • 33 citations

High frequency of donor chimerism after allogeneic transplantation of CD34+-selected peripheral blood cells.

1998 • 32 citations

Expression of CD134 (0X-40) on T cells during the first 100 days following allogeneic bone marrow transplantation as a marker for lymphocyte activation and therapy-resistant graft-versus-host disease

1999 • 29 citations

T-cell co-signalling molecules in graft-versus-host disease

2000 • 29 citations

T-cell depletion in allogeneic bone marrow transplantation: progress and problems.

1989 • 27 citations

SELECTIVE CD4+ T-CELL DEPLETION DOES NOT PREVENT GRAFT-VERSUS-HOST DISEASE1

1998 • 24 citations

LIGHT, a new TNF superfamily member, is essential for memory T helper cell‐mediated activation of dendritic cells

2003 • 20 citations

Immune Reconstitution following Stem Cell Transplantation

2004 • 18 citations

Expression of T cell activation antigen CD134 (OX40) has no predictive value for the occurrence or response to therapy of acute graft-versus-host disease in partial T cell-depleted bone marrow transplantation

1999 • 15 citations

Clinical value of the flow cytometric method for measuring lymphocyte subset activation: spontaneous activation of T-cell subpopulations is associated with acute GvHD

2003 • 8 citations

Limiting Dilution Analysis of Interleukin-2 Producing Helper T-cell Frequencies as a Tool in Allogeneic Hematopoietic Cell Transplantation

2005 • 5 citations