Fusion pore expansion in horse eosinophils is modulated by Ca2+ and protein kinase C via distinct mechanisms

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

Patch-clamp techniques for time-resolved capacitance measurements in single cells

1988 • 659 citations

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

1995 • 508 citations

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1984 • 506 citations

Currents through the fusion pore that forms during exocytosis of a secretory vesicle

1987 • 432 citations

Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins

1995 • 404 citations

Protein Kinase C Enhances Exocytosis from Chromaffin Cells by Increasing the Size of the Readily Releasable Pool of Secretory Granules

1996 • 395 citations

Bound and determined: A computer program for making buffers of defined ion concentrations

1992 • 335 citations

Synaptic vesicles retain their identity through the endocytic cycle

1998 • 271 citations

Properties of the fusion pore that forms during exocytosis of a mast cell secretory vesicle

1990 • 262 citations

GE: A GTP-Binding Protein Mediating Exocytosis

1990 • 256 citations

Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion

1995 • 249 citations

Multiple Forms of Endocytosis In Bovine Adrenal Chromaffin Cells

1997 • 187 citations

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

1994 • 186 citations

Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.

1996 • 177 citations

Tension in secretory granule membranes causes extensive membrane transfer through the exocytotic fusion pore.

1990 • 148 citations

Phase tracking: an improved phase detection technique for cell membrane capacitance measurements

1989 • 140 citations

Ca2+ triggers massive exocytosis in Chinese hamster ovary cells.

1996 • 129 citations

Staurosporine blocks evoked release of FM1-43 but not acetylcholine from frog motor nerve terminals

1995 • 118 citations

On the nature of calcium ion binding between phosphatidylserine lamellae

1986 • 118 citations

The exocytotic fusion pore modeled as a lipidic pore

1992 • 112 citations

The dynamics of exocytosis in human neutrophils.

1988 • 109 citations

Techniques and concepts in exocytosis: focus on mast cells

1991 • 109 citations

Focal exocytosis by eosinophils--compound exocytosis and cumulative fusion.

1993 • 100 citations

Time–resolved capacitance measurements: monitoring exocytosis in single cells

1991 • 92 citations

Synchronous exocytosis in Paramecium cells involves very rapid (less than or equal to 1 s), reversible dephosphorylation of a 65-kD phosphoprotein in exocytosis-competent strains.

1985 • 88 citations

Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells. The effects of protein kinase C(19-31), Ca/CaM kinase II(291-317), and staurosporine.

1990 • 87 citations

Cytosolic calcium facilitates release of secretory products after exocytotic vesicle fusion

1995 • 80 citations

Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells.

1993 • 75 citations

Degranulation of individual mast cells in response to Ca2+ and guanine nucleotides: an all-or-none event.

1993 • 74 citations

A novel Ca²⁺‐dependent step in exocytosis subsequent to vesicle fusion

1995 • 69 citations

Intracellular application of guanosine-5'-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils.

1990 • 66 citations

Protien phosphorylation and the dependence on Ca2+ and GTP-γ-S for exocytosis from permeabilised mast cells

1989 • 59 citations

GTPγS and phorbol ester act synergistically to stimulate both Ca²⁺‐independent secretion and phospholipase D activity in permeabilized human platelets

1993 • 58 citations

Covalent Modifications of G-Proteins

1993 • 57 citations

Differential inhibition of cytosolic and membrane‐derived protein kinase C activity by staurosporine and other kinase inhibitors

1995 • 46 citations

Factors affecting dense and alpha-granule secretion from electropermeabilized human platelets: Ca(2+)-independent actions of phorbol ester and GTP gamma S.

1990 • 40 citations

Calcium- and guanine-nucleotide-dependent exocytosis in permeabilized rat mast cells. Modulation by protein kinase C

1990 • 39 citations

ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells.

1990 • 39 citations

Phospholipase activation and secretion: evidence that PLA2, PLC, and PLD are not essential to exocytosis

1996 • 29 citations

Polarized exocytosis in mdck cells is regulated by phosphorylation

1995 • 29 citations

Three Distinct Fusion Processes during Eosinophil Degranulation

1994 • 14 citations

Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils

1994 • 9 citations