Inhibition of NF-κB and HIV-1 Long Terminal Repeat Transcriptional Activation by Inducible Nitric Oxide Synthase 2 Activity

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

Role of nitric oxide synthesis in macrophage antimicrobial activity

1991 • 1,547 citations

NO at work

1994 • 1,493 citations

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

1992 • 1,237 citations

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

1993 • 825 citations

Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

1995 • 707 citations

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.

1993 • 616 citations

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1989 • 590 citations

Nitric Oxide: A New Paradigm for Second Messengers

1995 • 566 citations

Nitric Oxide Protects Cultured Rat Hepatocytes from Tumor Necrosis Factor-α-induced Apoptosis by Inducing Heat Shock Protein 70 Expression

1997 • 527 citations

Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells.

1996 • 513 citations

Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation

1994 • 509 citations

A Molecular Redox Switch on p21

1997 • 488 citations

Inhibition of NF- B DNA Binding by Nitric Oxide

1996 • 479 citations

Nitric Oxide Modulates the Expression of Monocyte Chemoattractant Protein 1 in Cultured Human Endothelial Cells

1995 • 475 citations

Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication.

1993 • 470 citations

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras

1995 • 367 citations

Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds.

1993 • 353 citations

Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.

1993 • 348 citations

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.

1995 • 337 citations

THE BIOCHEMISTRY OF AIDS

1991 • 332 citations

Hydroxyurea as an Inhibitor of Human Immunodeficiency Virus-Type 1 Replication

1994 • 320 citations

Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism

1996 • 271 citations

Nitric oxide inhibits viral replication in murine myocarditis.

1996 • 249 citations

Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines.

1992 • 242 citations

Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes.

1995 • 233 citations

Nitric Oxide (NO) Donor Molecules

1995 • 221 citations

On the expression of nitric oxide synthase by human macrophages. Why no NO?

1995 • 218 citations

Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds

1993 • 198 citations

Binding of human tumor necrosis factor to high affinity receptors on HeLa and lymphoblastoid cells sensitive to growth inhibition.

1985 • 183 citations

Nitric Oxide Inhibits Macrophage-Colony Stimulating Factor Gene Transcription in Vascular Endothelial Cells

1995 • 180 citations

Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist.

1996 • 174 citations

Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain.

1995 • 154 citations

Synthesis of nitric oxide from L-arginine: a recently discovered pathway induced by cytokines with antitumour and antimicrobial activity

1991 • 153 citations

Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide

1992 • 144 citations

Dependence and Reversal of Nitric Oxide Production on NF-κ-B in Silica and Lipopolysaccharide Induced Macrophages

1995 • 130 citations

Monitoring Reactions of Nitric Oxide with Peptides and Proteins by Electrospray Ionization-Mass Spectrometry

1995 • 113 citations

Inhibitory effect of nitric oxide on the replication of a murine retrovirus in vitro and in vivo

1995 • 94 citations

Two cis-DNA elements involved in myeloid-cell-specific expression and gamma interferon (IFN-gamma) activation of the human high-affinity Fc gamma receptor gene: a novel IFN regulatory mechanism.

1993 • 76 citations

Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide, and superoxide anion (O2-) regulatory pathways.

1996 • 62 citations

Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma.

1996 • 59 citations

Reduction in tumor necrosis factor binding and cytotoxicity by hydrogen peroxide.

1990 • 22 citations

Increased Levels of Nitrite in the Sera of Children Infected with Human Immunodeficiency Virus Type 1

1996 • 21 citations

Involvement of nitric oxide synthase in antiproliferative activity of macrophages: Induction of the enzyme requires two different kinds of signal acting synergistically

1994 • 12 citations

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