A Role for a PDZ Protein in the Early Secretory Pathway for the Targeting of proTGF-α to the Cell Surface

Antibodies, a laboratory manual

1989 • 12,929 citations

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

1998 • 2,076 citations

An Essential Role for Ectodomain Shedding in Mammalian Development

1998 • 1,607 citations

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

Cell Surface Trafficking of Fas: A Rapid Mechanism of p53-Mediated Apoptosis

1998 • 752 citations

Binding of Neuroligins to PSD-95

1997 • 731 citations

Quality control in the secretory pathway

1995 • 679 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

ER Quality Control: The Cytoplasmic Connection

1997 • 528 citations

Depolarization and cAMP Elevation Rapidly Recruit TrkB to the Plasma Membrane of CNS Neurons

1998 • 521 citations

SIGNAL-MEDIATED SORTING OF MEMBRANE PROTEINS BETWEEN THE ENDOPLASMIC RETICULUM AND THE GOLGI APPARATUS

1996 • 506 citations

The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction

1989 • 482 citations

Syntenin, a PDZ protein that binds syndecan cytoplasmic domains

1997 • 413 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.

1994 • 377 citations

PACS-1 Defines a Novel Gene Family of Cytosolic Sorting Proteins Required for trans-Golgi Network Localization

1998 • 372 citations

Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor

1987 • 264 citations

The Physiology Of Transforming Growth Factor-α

1992 • 257 citations

Clustering Membrane Proteins: It's All Coming Together with the PSD-95/SAP90 Protein Family

1996 • 246 citations

Differential Association of Syntrophin Pairs with the Dystrophin Complex

1997 • 237 citations

Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels

1998 • 234 citations

Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition

1998 • 179 citations

The Three Human Syntrophin Genes Are Expressed in Diverse Tissues, Have Distinct Chromosomal Locations, and Each Bind to Dystrophin and Its Relatives

1996 • 172 citations

A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells.

1993 • 161 citations

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

1995 • 144 citations

The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor

1992 • 126 citations

A rapid and reliable DNA preparation method for screening a large number of yeast clones by polymerase chain reaction

1995 • 101 citations

Association of the transmembrane TGF-alpha precursor with a protein kinase complex.

1994 • 83 citations

Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene

1998 • 80 citations

PDZ Domains and the Formation of Protein Networks at the Plasma Membrane

1998 • 78 citations

The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing.

1997 • 76 citations

The cytoplasmic carboxy-terminal amino acid determines the subcellular localization of proTGF-α and membrane type matrix metalloprotease (MT1-MMP)

1999 • 73 citations

Cysteines 153 and 154 of Transmembrane Transforming Growth Factor-α Are Palmitoylated and Mediate Cytoplasmic Protein Association

1996 • 68 citations

Analysis of transport and targeting of syndecan-1: effect of cytoplasmic tail deletions.

1994 • 67 citations

gp74 a membrane glycoprotein of the cis-Golgi network that cycles through the endoplasmic reticulum and intermediate compartment

1994 • 44 citations

A truncated thyroxine-binding globulin due to a frameshift mutation is retained within the rough endoplasmic reticulum: a possible mechanism of complete thyroxine-binding globulin deficiency in Japanese.

1994 • 25 citations

Study of the roles of proline 391 and a highly conserved sequence in the carboxyl-terminal region of members of the serpin family in the secretion of alpha 1-proteinase inhibitor.

1994 • 15 citations