Classes of autonomously replicating sequences are found among early-replicating monkey DNA

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Complete sequence of bovine mitochondrial DNA conserved features of the mammalian mitochondrial genome

1982 • 1,491 citations

On the mechanism of DNA replication in mammalian chromosomes

1968 • 950 citations

Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome

1988 • 678 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Repetitive Sequences in Eukaryotic DNA and their Expression

1982 • 575 citations

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

1985 • 502 citations

Isolation of Mutants of an Animal Virus in Bacteria

1980 • 341 citations

Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain

1990 • 287 citations

Isolation of human sequences that replicate autonomously in human cells.

1989 • 244 citations

The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication origin.

1989 • 233 citations

Direct Evidence for DNA Bending at the Lambda Replication Origin

1987 • 233 citations

Mapping replication units in animal cells

1989 • 232 citations

Bent DNA at a yeast autonomously replicating sequence

1986 • 217 citations

Highly Reiterated Sequences of SIMIANSIMIANSIMIANSIMIANSIMIAN

1978 • 208 citations

A yeast replication origin consists of multiple copies of a small conserved sequence

1988 • 194 citations

The ease of DNA unwinding as a determinant of initiation at yeast replication origins

1988 • 193 citations

Sequence-induced DNA curvature at the bacteriophage λ origin of replication

1985 • 171 citations

Domain Structure of the Simian Virus 40 Core Origin of Replication

1986 • 160 citations

Functional organization of the simian virus 40 origin of DNA replication.

1986 • 157 citations

Possible function of the c-myc product: promotion of cellular DNA replication.

1987 • 156 citations

Initiation protein induced helix destabilization at the λ origin: A prepriming step in DNA replication

1988 • 147 citations

Characterization of an Episome Produced in Hamster Cells that Amplify a Transfected CAD Gene at High Frequency: Functional Evidence for a Mammalian Replication Origin

1987 • 137 citations

High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.

1989 • 134 citations

Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference

1984 • 131 citations

The Adenine-Thymine Domain of the Simian Virus 40 Core Origin Directs DNA Bending and Coordinately Regulates DNA Replication

1986 • 130 citations

Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element.

1989 • 130 citations

Static and Initiator Protein-Enhanced Bending of DNA at a Replication Origin

1986 • 129 citations

Conformational changes in a replication origin induced by an initiator protein

1985 • 115 citations

Origin of replication in episomal bovine papilloma virus type 1 DNA isolated from transformed cells.

1984 • 102 citations

Rate of replication of the murine immunoglobulin heavy-chain locus: evidence that the region is part of a single replicon.

1987 • 97 citations

Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line.

1989 • 96 citations

The remarkable instability of replication loops provides a general method for the isolation of origins of DNA replication

1981 • 92 citations

Characterization of human chromosomal DNA sequences which replicate autonomously inSaccharomyces cerevisiae

1984 • 86 citations

Characterization of an episome produced in hamster cells that amplify a transfected CAD gene at high frequency: functional evidence for a mammalian replication origin.

1987 • 80 citations

Domain structure of the simian virus 40 core origin of replication.

1986 • 78 citations

The coordinate replication of the human beta-globin gene domain reflects its transcriptional activity and nuclease hypersensitivity.

1988 • 74 citations

Opposite replication polarity of the germ line c-myc gene in HeLa cells compared with that of two Burkitt lymphoma cell lines.

1989 • 73 citations

Effect of anti-cruciform DNA monoclonal antibodies on DNA replication.

1988 • 72 citations

The adenine-thymine domain of the simian virus 40 core origin directs DNA bending and coordinately regulates DNA replication.

1986 • 55 citations

Nucleotides in the Polyomavirus Enhancer that Control Viral Transcription and DNA Replication

1987 • 48 citations

Cloning of nascent monkey DNA synthesized early in the cell cycle.

1985 • 47 citations

Properties of some monkey DNA sequences obtained by a procedure that enriches for DNA replication origins.

1985 • 46 citations

Sequence similarities among monkey ori-enriched (ors) fragments

1990 • 45 citations

Mammalian DNA enriched for replication origins is enriched for snap-back sequences

1984 • 44 citations

Polarity of DNA replication through the avian alpha-globin locus.

1986 • 44 citations

The dynamic distribution and quantification of DNA cruciforms in eukaryotic nuclei

1990 • 39 citations

Isolation and Characterization of Sequences from Mouse Chromosomal DNA with ARS Function in Yeasts

1983 • 39 citations

DNA synthesis is initiated at two positions within the origin of replication of plasmid R1162

1987 • 38 citations

Opposite Replication Polarities of Transcribed and Nontranscribed Histone H5 Genes

1988 • 38 citations

Binding of simian virus 40 a protein to DNA with deletions at the origin of replication

1984 • 32 citations

Isolation and characterization of sequences from mouse chromosomal DNA with ARS function in yeasts.

1983 • 29 citations

Bends in SV40 DNA: use of mutagenesis to identify the critical bases involved

1988 • 27 citations

DNA replication in synchronized cultured mammalian cells

1972 • 27 citations

Opposite replication polarities of transcribed and nontranscribed histone H5 genes.

1988 • 22 citations

Bent DNA structures associated with several origins of replication are recognized by a unique enzyme from trypanosomatids

1988 • 20 citations

DNA looping induced by bacteriophage λ O protein: Implications for formation of higher order structures at the gl origin of replication

1989 • 19 citations

Nuclease S1 sensitive sites in parental DNA of cold- and temperature-sensitive mammalian cells

1982 • 16 citations

Evaluation of autonomous plasmid replication in transfected mammalian cells

1988 • 14 citations

DpnI assay for DNA replication in animal cells: enzyme-resistant material can result from factors not related to replication

1988 • 14 citations

Cloned Mouse DNA Fragments Can Replicate in a Simian Virus 40 T Antigen-Dependent System In Vivo and In Vitro

1985 • 14 citations

Cloning of the p53-dependent origin of cellular DNA replication.

1988 • 11 citations

Early initiation of bovine satellite I DNA replication

1982 • 10 citations

Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication.

1987 • 9 citations

Cloned mouse DNA fragments can replicate in a simian virus 40 T antigen-dependent system in vivo and in vitro.

1985 • 7 citations