Cannabinoid Receptors are Coupled to Stimulation of Insulin Secretion from Mouse MIN6 β-cells

Molecular characterization of a peripheral receptor for cannabinoids

1993 • 4,950 citations

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1990 • 4,933 citations

The orphan receptor GPR55 is a novel cannabinoid receptor

2007 • 1,487 citations

Identification and Functional Characterization of Brainstem Cannabinoid CB ₂ Receptors

2005 • 1,432 citations

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

2005 • 976 citations

The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance

2005 • 831 citations

Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol

2002 • 776 citations

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

2008 • 658 citations

Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration

2003 • 641 citations

Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and β-Pancreatic Cells and in Obesity and Hyperglycemia

2006 • 632 citations

Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity

2006 • 513 citations

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1993 • 430 citations

Evidence for novel cannabinoid receptors

2005 • 388 citations

In silico patent searching reveals a new cannabinoid receptor

2005 • 339 citations

Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lepob/Lepob mice

2004 • 316 citations

Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets.

1999 • 242 citations

An introduction to the endocannabinoid system: from the early to the latest concepts

2009 • 235 citations

Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High‐fat Diet

2008 • 188 citations

Presence of functional cannabinoid receptors in human endocrine pancreas

2007 • 187 citations

Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets.

1988 • 173 citations

2-Arachidonoylglycerol, a Putative Endogenous Cannabinoid Receptor Ligand, Induces Rapid, Transient Elevation of Intracellular Free Ca2+in Neuroblastoma × Glioma Hybrid NG108-15 Cells

1996 • 167 citations

The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation

2009 • 164 citations

Protein phosphorylation in electrically permeabilized islets of Langerhans. Effects of Ca2+, cyclic AMP, a phorbol ester and noradrenaline

1988 • 154 citations

The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract

2005 • 142 citations

Role of cannabinoid CB2 receptors in glucose homeostasis in rats

2007 • 118 citations

Activation of cannabinoid CB1 receptors induces glucose intolerance in rats

2006 • 109 citations

Effects of marihuana use on body weight and caloric intake in humans

1976 • 108 citations

Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet β-cells via CB1 receptors

2007 • 105 citations

Inhibition of Lipase Activity and Lipolysis in Rat Islets Reduces Insulin Secretion

2004 • 72 citations

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma β-cells

2007 • 68 citations

Expression and function of cannabinoid receptors in mouse islets

2010 • 65 citations

Characterisation of the Insulinotropic Activity of an Aqueous Extract of <i>Gymnema Sylvestre</i> in Mouse β-Cells and Human Islets of Langerhans

2009 • 61 citations

The cannabinoid agonist DALN positively modulates L-type voltage-dependent calcium-channels in N18TG2 neuroblastoma cells

2002 • 56 citations

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

2009 • 49 citations

A Key Role for β-Cell Cytosolic Phospholipase A2 in the Maintenance of Insulin Stores But Not in the Initiation of Insulin Secretion

2002 • 45 citations

The cannabinoid receptor: Biochemical and cellular properties in neuroblastoma cells

1991 • 44 citations

The cannabinoid CB1 receptor is expressed in pancreatic δ-cells

2008 • 43 citations

Insulin, Glucagon, and Somatostatin Secretion by Cultured Rat Islet Cell Tumor and Its Clones

1984 • 41 citations

The role of the pancreatic endocannabinoid system in glucose metabolism

2009 • 34 citations

Cytological and immunocytochemical characterization of the insulin secreting insulinoma cell line RINm5F

2004 • 10 citations