Presence of functional cannabinoid receptors in human endocrine pancreas

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1995 • 2,837 citations

Determination and characterization of a cannabinoid receptor in rat brain.

1988 • 2,339 citations

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

1996 • 2,079 citations

The molecular logic of endocannabinoid signalling

2003 • 1,898 citations

Leptin-regulated endocannabinoids are involved in maintaining food intake

2001 • 1,557 citations

Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

2005 • 1,509 citations

A second endogenous cannabinoid that modulates long-term potentiation

1997 • 1,474 citations

Identification and Functional Characterization of Brainstem Cannabinoid CB ₂ Receptors

2005 • 1,432 citations

Brain monoglyceride lipase participating in endocannabinoid inactivation

2002 • 1,307 citations

Automated Method for Isolation of Human Pancreatic Islets

1988 • 1,282 citations

Effect of Rimonabant, a Cannabinoid-1 Receptor Blocker, on Weight and Cardiometabolic Risk Factors in Overweight or Obese Patients

2006 • 1,226 citations

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

2003 • 1,123 citations

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

2005 • 976 citations

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

2005 • 895 citations

The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance

2005 • 831 citations

Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

2006 • 788 citations

Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol

2002 • 776 citations

Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study

2006 • 746 citations

Endocannabinoid control of food intake and energy balance

2005 • 734 citations

Activation of the Peripheral Endocannabinoid System in Human Obesity

2005 • 677 citations

Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and β-Pancreatic Cells and in Obesity and Hyperglycemia

2006 • 632 citations

A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding

2002 • 489 citations

Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1).

1999 • 368 citations

Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB1

2000 • 362 citations

Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes

1995 • 353 citations

Loss of Connexin36 Channels Alters β-Cell Coupling, Islet Synchronization of Glucose-Induced Ca2+ and Insulin Oscillations, and Basal Insulin Release

2005 • 344 citations

Cannabinoids, opioids and eating behavior: The molecular face of hedonism?

2005 • 327 citations

3-(1′,1′-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor

1999 • 276 citations

Cannabinoid receptors regulate Ca2+ signals and insulin secretion in pancreatic β-cell

2005 • 257 citations

Immunohistochemical localization of the neural cannabinoid receptor in rat brain

1998 • 220 citations

Genetic Impairment of Frontocortical Endocannabinoid Degradation and High Alcohol Preference

2006 • 164 citations

Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes

2006 • 163 citations

Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 to rodent brain cannabinoid receptors

1997 • 144 citations

Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404

2000 • 131 citations

Role of cannabinoid CB2 receptors in glucose homeostasis in rats

2007 • 118 citations

Characterization of Somatostatin Receptor Subtype-Specific Regulation of Insulin and Glucagon Secretion: An in Vitro Study on Isolated Human Pancreatic Islets

2006 • 118 citations

Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole – LH 21

2006 • 114 citations

Activation of cannabinoid CB1 receptors induces glucose intolerance in rats

2006 • 109 citations

Resistance to Diet-Induced Obesity in μ-Opioid Receptor–Deficient Mice

2005 • 102 citations

Immunohistochemical characterisation and localisation of cannabinoid CB1 receptor protein in the rat vestibular nucleus complex and the effects of unilateral vestibular deafferentation

2004 • 30 citations

Internal Assessment of a Novel Islet Isolation Facility in Spain

2005 • 1 citations